World's Best Scientists 2026 revealed!

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Immunology

D-Index
110
Citations
51130
World Ranking
497
National Ranking
300

Medicine

D-Index
110
Citations
51169
World Ranking
5501
National Ranking
2964

Research.com Recognitions

  • 2010 - Distinguished Service Award, Clinical Immunology Society
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

George C. Tsokos is affiliated with Harvard Medical School in the United States. Their research is predominantly situated within medicine, with a significant focus on immunology and microbiology. Subfields of specialization include immunology, rheumatology, oncology, molecular biology, and genetics.

The scientist's work extensively addresses topics such as systemic lupus erythematosus research, T-cell and B-cell immunology, immune cell function and interaction, CAR-T cell therapy research, immunotherapy and immune responses, cancer immunotherapy and biomarkers, and renal diseases and glomerulopathies.

Recent notable publications authored by George C. Tsokos include:

  • Autoimmunity and organ damage in systemic lupus erythematosus, 2020, Nature Immunology

Other prominent papers in the field related to their research interests include:

  • Glutathione peroxidase 4-regulated neutrophil ferroptosis induces systemic autoimmunity, 2021, Nature Immunology
  • T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy, 2020, Nature Reviews Rheumatology
  • The role of platelets in immune-mediated inflammatory diseases, 2023, Nature reviews. Immunology
  • An Autoimmunogenic and Proinflammatory Profile Defined by the Gut Microbiota of Patients With Untreated Systemic Lupus Erythematosus, 2020, Arthritis & Rheumatology

Frequent co-authors collaborating with George C. Tsokos include:

  • Maria Tsokos
  • Hao Li
  • Abhigyan Satyam
  • Marc Scherlinger
  • Rhea Bhargava

Common publication venues for their research are:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • Clinical Immunology
  • Arthritis & Rheumatology
  • Nature Communications
  • Current Opinion in Rheumatology

The scientist has been recognized with several awards, including the Distinguished Service Award from the Clinical Immunology Society in 2010 and being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2007. They are also a member of the Association of American Physicians.

Best Publications

  • Systemic Lupus Erythematosus

    George C. Tsokos

  • Heat Shock Protein 70 kDa ☆: Molecular Biology, Biochemistry, and Physiology

    Juliann G. Kiang;George C. Tsokos

  • New insights into the immunopathogenesis of systemic lupus erythematosus

    George C. Tsokos;Mindy S. Lo;Patricia Costa Reis;Kathleen E. Sullivan

  • Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

    José C. Crispín;Mohammed Oukka;George Bayliss;Robert A. Cohen

  • T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis.

    S Shivakumar;G C Tsokos;S K Datta

  • Autoimmunity and organ damage in systemic lupus erythematosus

    George C. Tsokos

  • Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. Deficient expression of the T cell receptor zeta chain.

    S.-N. C. Liossis;X. Z. Ding;G. J. Dennis;G. C. Tsokos

  • Pathogenesis of human systemic lupus erythematosus: recent advances

    José C. Crispín;Stamatis-Nick C. Liossis;Katalin Kis-Toth;Linda A. Lieberman

  • Pathogenesis of Human Systemic Lupus Erythematosus: A Cellular Perspective

    Vaishali R. Moulton;Abel Suarez-Fueyo;Esra Meidan;Esra Meidan;Hao Li

  • Glutathione peroxidase 4–regulated neutrophil ferroptosis induces systemic autoimmunity

    Pengchong Li;Pengchong Li;Mengdi Jiang;Mengdi Jiang;Ketian Li;Ketian Li;Hao Li

  • The Role of IL-23/IL-17 Axis in Lupus Nephritis

    Zheng Zhang;Vasileios C. Kyttaris;George C. Tsokos

  • Efficacy and safety of ustekinumab, an IL-12 and IL-23 inhibitor, in patients with active systemic lupus erythematosus: results of a multicentre, double-blind, phase 2, randomised, controlled study

    Ronald F van Vollenhoven;Ronald F van Vollenhoven;Bevra H Hahn;George C Tsokos;Carrie L Wagner

  • Interleukin‐17 and systemic lupus erythematosus: current concepts

    A. Nalbandian;Jose Crispin;G. C. Tsokos

  • T cells as therapeutic targets in SLE

    José C. Crispín;Vasileios C. Kyttaris;Cox Terhorst;George C. Tsokos

  • Pathogenic anti-DNA autoantibody-inducing T helper cell lines from patients with active lupus nephritis: isolation of CD4-8- T helper cell lines that express the gamma delta T-cell antigen receptor.

    Sumati Rajagopalan;Tracy Zordan;George C. Tsokos;Syamal K. Datta

  • Regulatory T cells in the treatment of disease

    Amir Sharabi;Maria G. Tsokos;Ying Ding;Thomas R. Malek

  • T cell metabolism: new insights in systemic lupus erythematosus pathogenesis and therapy.

    Amir Sharabi;Amir Sharabi;Amir Sharabi;George C Tsokos

  • T cell signaling abnormalities contribute to aberrant immune cell function and autoimmunity

    Vaishali R. Moulton;George C. Tsokos

  • B CELLS FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS DISPLAY ABNORMAL ANTIGEN RECEPTOR-MEDIATED EARLY SIGNAL TRANSDUCTION EVENTS

    S.-N. C. Liossis;B. Kovacs;G. Dennis;G. M. Kammer

  • Cutting Edge: IL-23 Receptor Deficiency Prevents the Development of Lupus Nephritis in C57BL/6–lpr/lpr Mice

    Vasileios C. Kyttaris;Zheng Zhang;Vijay K. Kuchroo;Vijay K. Kuchroo;Mohamed Oukka;Mohamed Oukka

  • Immunopathogenesis and spectrum of infections in systemiclupus erythematosus

    A.G. Iliopoulos;G.C. Tsokos

Frequent Co-Authors

Vasileios C. Kyttaris
Vasileios C. Kyttaris Beth Israel Deaconess Medical Center
James E. Balow
James E. Balow National Institutes of Health
Thomas Rauen
Thomas Rauen RWTH Aachen University
Christian M. Hedrich
Christian M. Hedrich University of Liverpool
Maria Tsokos
Maria Tsokos Beth Israel Deaconess Medical Center
Cox Terhorst
Cox Terhorst Beth Israel Deaconess Medical Center
Bevra H. Hahn
Bevra H. Hahn University of California, Los Angeles
Dimitrios T. Boumpas
Dimitrios T. Boumpas National and Kapodistrian University of Athens
John D. Lambris
John D. Lambris University of Pennsylvania
Ronald F. van Vollenhoven
Ronald F. van Vollenhoven University of Amsterdam

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