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Immunology

D-Index
60
Citations
10307
World Ranking
3364
National Ranking
291

Overview

Christian M. Hedrich is affiliated with the University of Liverpool in the United Kingdom and has contributed extensively to the fields of medicine, immunology, and rheumatology. Their research encompasses a range of topics including systemic lupus erythematosus, osteomyelitis, autoimmune and inflammatory disorders, and infectious diseases.

The scientist's work is prominently featured in several publication venues, with multiple contributions to:

  • Clinical Immunology
  • Annals of the Rheumatic Diseases
  • Lara D. Veeken
  • Frontiers in Pediatrics
  • Journal of Translational Autoimmunity

Frequent collaborators include Michael W. Beresford, Eve Smith, Amandine Charras, Coziana Ciurtin, and Eslam Al-Abadi, demonstrating a collaborative approach across related disciplines.

The subfields of study most associated with Christian M. Hedrich's research are:

  • Rheumatology
  • Immunology
  • Surgery
  • Molecular Biology
  • Hematology

Key main topics in their work cover:

  • Systemic Lupus Erythematosus Research
  • Osteomyelitis and Bone Disorders Research
  • Orthopedic Infections and Treatments
  • Infectious Diseases and Tuberculosis
  • T-cell and B-cell Immunology
  • Autoimmune and Inflammatory Disorders Research
  • Inflammasome and immune disorders

Notable recent publications by Christian M. Hedrich include:

  • "New Insights into Adult and Paediatric Chronic Non-bacterial Osteomyelitis CNO," 2020, Current Rheumatology Reports
  • "COVID-19: Immunology and treatment options," 2020, Clinical Immunology
  • "Systemic Lupus Erythematosus in Children and Young People," 2021, Current Rheumatology Reports
  • "Chronic nonbacterial osteomyelitis (CNO) and chronic recurrent multifocal osteomyelitis (CRMO)," 2021, Journal of Translational Autoimmunity
  • "SARS-CoV-2 infections in children and young people," 2020, Clinical Immunology

This collection of research papers highlights involvement in both clinical immunology and rheumatological disorders, with an emphasis on autoimmune conditions and infectious disease intersections within pediatric and adult populations.

Best Publications

  • COVID-19: Immunology and treatment options.

    Susanna Felsenstein;Jenny A. Herbert;Paul S. McNamara;Christian M. Hedrich;Christian M. Hedrich

  • The role of epigenetics in autoimmune/inflammatory disease

    Anna Elisa Andrea Surace;Christian M. Hedrich;Christian M. Hedrich

  • Chronic Recurrent Multifocal Osteomyelitis (CRMO): Presentation, Pathogenesis, and Treatment

    Sigrun R. Hofmann;Franz Kapplusch;Hermann J. Girschick;Henner Morbach

  • Cell type-specific regulation of IL-10 expression in inflammation and disease.

    Christian M. Hedrich;Christian M. Hedrich;Jay H. Bream

  • Autoinflammatory bone disorders with special focus on chronic recurrent multifocal osteomyelitis (CRMO).

    Christian M Hedrich;Sigrun R Hofmann;Jessica Pablik;Henner Morbach

  • Distinct interferon signatures and cytokine patterns define additional systemic autoinflammatory diseases

    Adriana A. de Jesus;Yangfeng Hou;Stephen Brooks;Louise Malle

  • Consensus Treatment Plans for Chronic Nonbacterial Osteomyelitis Refractory to Nonsteroidal Antiinflammatory Drugs and/or With Active Spinal Lesions.

    Yongdong Zhao;Eveline Y Wu;Melissa S Oliver;Ashley M Cooper

  • CaMK4-dependent activation of AKT/mTOR and CREM-α underlies autoimmunity-associated Th17 imbalance

    Tomohiro Koga;Christian M. Hedrich;Christian M. Hedrich;Masayuki Mizui;Nobuya Yoshida

  • Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury

    S.R. Hofmann;A. Rösen-Wolff;G.C. Tsokos;C.M. Hedrich;C.M. Hedrich

  • Epigenetic mechanisms in systemic lupus erythematosus and other autoimmune diseases

    Christian M. Hedrich;George C. Tsokos

  • Juvenile-onset systemic lupus erythematosus: Update on clinical presentation, pathophysiology and treatment options.

    Eve Mary Dorothy Smith;Eve Mary Dorothy Smith;Hanna Lythgoe;Angela Midgley;Michael William Beresford

  • Stat3 promotes IL-10 expression in lupus T cells through trans-activation and chromatin remodeling

    Christian M. Hedrich;Christian M. Hedrich;Thomas Rauen;Thomas Rauen;Sokratis A. Apostolidis;Alexandros P. Grammatikos

  • Treatment Response and Longterm Outcomes in Children with Chronic Nonbacterial Osteomyelitis

    Anja Schnabel;Ursula Range;Gabriele Hahn;Reinhard Berner

  • Chilblain lupus erythematosus—a review of literature

    C M Hedrich;B Fiebig;F H Hauck;S Sallmann

  • Systemic Lupus Erythematosus in Children and Young People.

    A. Charras;E. Smith;C.M. Hedrich

  • Unexpectedly high incidences of chronic non-bacterial as compared to bacterial osteomyelitis in children.

    A. Schnabel;U. Range;G. Hahn;T. Siepmann

  • TCRαβ + CD3 + CD4 − CD8 − (double negative) T cells in autoimmunity

    Unknown

  • DNA methylation in systemic lupus erythematosus.

    Christian M Hedrich;Katrin Mäbert;Thomas Rauen;George C Tsokos

  • The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathway in T-cells from controls and systemic lupus erythematosus patients.

    Katsue Sunahori;Kamalpreet Nagpal;Christian M. Hedrich;Masayuki Mizui

  • Chronic Nonbacterial Osteomyelitis: Pathophysiological Concepts and Current Treatment Strategies.

    Sigrun R Hofmann;Anja Schnabel;Angela Rösen-Wolff;Henner Morbach

  • Autoinflammatory bone disorders.

    Henner Morbach;Christian M. Hedrich;Meinrad Beer;Meinrad Beer;Hermann J. Girschick

  • SARS-CoV-2 infections in children and young people.

    Susanna Felsenstein;Christian M. Hedrich

  • cAMP-responsive Element Modulator (CREM)α Protein Induces Interleukin 17A Expression and Mediates Epigenetic Alterations at the Interleukin-17A Gene Locus in Patients with Systemic Lupus Erythematosus

    Thomas Rauen;Christian M. Hedrich;Yuang-Taung Juang;Klaus Tenbrock

Frequent Co-Authors

Thomas Rauen
Thomas Rauen RWTH Aachen University
George C. Tsokos
George C. Tsokos Harvard Medical School
Vasileios C. Kyttaris
Vasileios C. Kyttaris Beth Israel Deaconess Medical Center
Ian N. Bruce
Ian N. Bruce University of Manchester
Jay H. Bream
Jay H. Bream Johns Hopkins University
Dirk Foell
Dirk Foell University of Münster
Ronald M. Laxer
Ronald M. Laxer University of Toronto
Klaus Warnatz
Klaus Warnatz University of Freiburg
E. Richard Stanley
E. Richard Stanley Albert Einstein College of Medicine
Horst von Bernuth
Horst von Bernuth Charité - University Medicine Berlin

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