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Elizabeth D. Mellins

Elizabeth D. Mellins

D-Index & Metrics

Microbiology

D-Index
61
Citations
13173
World Ranking
3003
National Ranking
1191

Research.com Recognitions

  • 2021 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2005 - AAI Distinguished Service Award, American Association of Immunologists For dedicated leadership as Director of the AAI Advanced Course in Immunology, 2002-2004

Overview

Elizabeth D. Mellins is affiliated with Stanford University in the United States. Their research spans multiple areas within medicine and immunology, focusing extensively on autoimmune and inflammatory disorders, adolescent and pediatric healthcare, and rheumatoid arthritis research and therapies.

The main fields of study for Mellins include:

  • Medicine
  • Immunology and Microbiology

More specifically, their work encompasses subfields such as:

  • Immunology
  • Hematology
  • Speech and Hearing
  • Rheumatology
  • Molecular Biology

Key research topics covered by Mellins involve:

  • Autoimmune and Inflammatory Disorders Research
  • Adolescent and Pediatric Healthcare
  • Rheumatoid Arthritis Research and Therapies
  • Immunotherapy and Immune Responses
  • Monoclonal and Polyclonal Antibodies Research
  • T-cell and B-cell Immunology
  • Immune Cell Function and Interaction

Mellins has published extensively in a range of venues, with frequent contributions to:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Annals of the Rheumatic Diseases
  • Frontiers in Immunology
  • Arthritis & Rheumatology

Recent notable papers include:

  • "Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity," 2022, published in Science Translational Medicine
  • "Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation," 2021, published in Nature Immunology
  • "Severe delayed hypersensitivity reactions to IL-1 and IL-6 inhibitors link to common HLA-DRB1*15 alleles," 2021, published in Annals of the Rheumatic Diseases
  • "New insights into B cells as antigen presenting cells," 2021, published in Current Opinion in Immunology
  • "Shortwave-infrared-light-emitting probes for the in vivo tracking of cancer vaccines and the elicited immune responses," 2023, published in Nature Biomedical Engineering

Frequent collaborators in Mellins' research include:

  • Claudia Macaubas
  • Vivian E Saper
  • Debopam Ghosh
  • Wei Jiang
  • Purvesh Khatri

The scientist has received awards such as the Distinguished Fellows of the American Association of Immunologists in 2021, and the AAI Distinguished Service Award in 2005 for leadership roles within the association.

Best Publications

  • A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

    Thomas Spies;Maureen Bresnahan;Seiamak Bahrain;Daniele Arnold

  • The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.

    Partho Ghosh;Miguel Amaya;Elizabeth Mellins;Don C. Wiley;Don C. Wiley

  • Mediation by HLA-DM of dissociation of peptides from HLA-DR

    Victor S. Sloan;Patricia Cameron;Gene Porter;Maureen Gammon

  • An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules.

    Phillip Morris;Jeffrey Shaman;Michelle Attaya;Miguel Amaya

  • Pathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions

    Elizabeth D. Mellins;Claudia Macaubas;Alexei A. Grom

  • Precarious balance: Th17 cells in host defense.

    Ariana Peck;Elizabeth D. Mellins

  • Plasticity of T-cell phenotype and function: the T helper type 17 example.

    Ariana Peck;Elizabeth D Mellins

  • Macrophage activation syndrome: advances towards understanding pathogenesis

    Alexei A Grom;Elizabeth D Mellins

  • Epithelial MHC Class II Expression and Its Role in Antigen Presentation in the Gastrointestinal and Respiratory Tracts

    Jonathan E. Wosen;Dhriti Mukhopadhyay;Claudia Macaubas;Elizabeth D. Mellins

  • T Cell-Mediated Autoimmune Disease Due to Low-Affinity Crossreactivity to Common Microbial Peptides

    Maria Harkiolaki;Samantha L. Holmes;Samantha L. Holmes;Pia Svendsen;Jon W. Gregersen

  • Emergent high fatality lung disease in systemic juvenile arthritis

    Vivian E Saper;Guangbo Chen;Gail H Deutsch;Gail H Deutsch;R Paul Guillerman

  • The IL-23/IL-17 axis in psoriatic arthritis.

    Erika Suzuki;Elizabeth D. Mellins;M. Eric Gershwin;Frank O. Nestle

  • Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression

    Robert Busch;Cornelia H Rinderknecht;Sujin Roh;Andrew W Lee

  • Early non-neutralizing, afucosylated antibody responses are associated with COVID-19 severity

    Unknown

  • Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease: Characterization and Risk Factors.

    Grant S. Schulert;Shima Yasin;Brenna Carey;Claudia Chalk

  • HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis

    Michael J. Ombrello;Elaine F. Remmers;Ioanna Tachmazidou;Alexei Grom;Alexei Grom

  • Modulation of Major Histocompatibility Class II Protein Expression by Varicella-Zoster Virus

    Allison Abendroth;Barry Slobedman;Eunice Lee;Elizabeth Mellins

  • Oligoarticular and polyarticular JIA: epidemiology and pathogenesis

    Claudia Macaubas;Khoa Nguyen;Diana Milojevic;Jane L. Park

  • Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications.

    Michael J Ombrello;Victoria L Arthur;Elaine F Remmers;Anne Hinks

  • Determination of the HLA-DM Interaction Site on HLA-DR Molecules

    Robert C. Doebele;Robert C. Doebele;Robert Busch;Hyman M. Scott;Achal Pashine

  • Susceptibility of Immature and Mature Langerhans Cell-Type Dendritic Cells to Infection and Immunomodulation by Human Cytomegalovirus

    Laura Hertel;Vashti G. Lacaille;Herbert Strobl;Elizabeth D. Mellins

  • Lymphocyte activation provokes modification of a lymphocyte-specific protein tyrosine kinase (p56lck).

    J D Marth;D B Lewis;M P Cooke;E D Mellins

Frequent Co-Authors

Susan D. Thompson
Susan D. Thompson Cincinnati Children's Hospital Medical Center
Lawrence J. Stern
Lawrence J. Stern University of Massachusetts Chan Medical School
John F. Bohnsack
John F. Bohnsack University of Utah
Lucy R. Wedderburn
Lucy R. Wedderburn University College London
Purvesh Khatri
Purvesh Khatri Stanford University
Wendy Thomson
Wendy Thomson University of Manchester
Elaine F. Remmers
Elaine F. Remmers National Institutes of Health
Mark M. Davis
Mark M. Davis Stanford University
Carl D. Langefeld
Carl D. Langefeld Wake Forest University
Marco Gattorno
Marco Gattorno Istituto Giannina Gaslini

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