World's Best Scientists 2026 revealed!
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Hidde L. Ploegh
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Immunology
USA
2026
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Biology and Biochemistry
USA
2025

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Best Scientists 165 1045 960 619 557 807 99742
Immunology 163 71 68 49 47 764 99420

Hidde L. Ploegh publications per year

The chart shows the history of publications by Hidde L. Ploegh between 1979 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Hidde L. Ploegh published across 47 years, from 1979 to 2025, averaging 19.1 papers a year. Output peaked at 68 publications in 2023. 34 of the 896 publications appeared in the last two years.

No. of publications
20 40 60
Bar chart. Horizontal axis: year, 1979 to 2025. Vertical axis: number of publications, 0 to 68. Peak 68 publications in 2023. 1979: 2 publications 1980: 4 publications 1981: 3 publications 1982: 2 publications 1983: 5 publications 1984: 3 publications 1985: 4 publications 1986: 9 publications 1987: 8 publications 1988: 10 publications 1989: 8 publications 1990: 11 publications 1991: 8 publications 1992: 17 publications 1993: 20 publications 1994: 13 publications 1995: 18 publications 1996: 13 publications 1997: 20 publications 1998: 18 publications 1999: 12 publications 2000: 17 publications 2001: 23 publications 2002: 28 publications 2003: 20 publications 2004: 34 publications 2005: 26 publications 2006: 29 publications 2007: 27 publications 2008: 19 publications 2009: 26 publications 2010: 16 publications 2011: 26 publications 2012: 29 publications 2013: 33 publications 2014: 42 publications 2015: 29 publications 2016: 42 publications 2017: 28 publications 2018: 21 publications 2019: 15 publications 2020: 19 publications 2021: 22 publications 2022: 15 publications 2023: 68 publications 2024: 17 publications 2025: 17 publications
1979 2025

896 publications in total across all disciplines

View publications per year as a table
Hidde L. Ploegh: publications per year, 1979 to 2025
Year Publications
1979 2
1980 4
1981 3
1982 2
1983 5
1984 3
1985 4
1986 9
1987 8
1988 10
1989 8
1990 11
1991 8
1992 17
1993 20
1994 13
1995 18
1996 13
1997 20
1998 18
1999 12
2000 17
2001 23
2002 28
2003 20
2004 34
2005 26
2006 29
2007 27
2008 19
2009 26
2010 16
2011 26
2012 29
2013 33
2014 42
2015 29
2016 42
2017 28
2018 21
2019 15
2020 19
2021 22
2022 15
2023 68
2024 17
2025 17
Total 896
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Hidde L. Ploegh publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Hidde L. Ploegh sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 76 bars. Horizontal axis: publications, 62–71 to 807+. Vertical axis: number of scientists, 0 to 189. Most scientists, 189, have 152–161 publications. The last bar groups every scientist with 807 publications or more. The highlighted bar, 762–771 publications, is where this scientist sits. 62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 69 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientist 807+ publications: 100 scientists
62–71 publications 807+

This scientist: 764 publications — 97th percentile

97% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

View publications distribution as a table
Number of Immunology scientists by publication count, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
Publications Scientists This scientist
62–71 9
72–81 23
82–91 40
92–101 72
102–111 86
112–121 108
122–131 150
132–141 160
142–151 159
152–161 189
162–171 166
172–181 181
182–191 188
192–201 187
202–211 178
212–221 158
222–231 168
232–241 159
242–251 160
252–261 148
262–271 116
272–281 125
282–291 115
292–301 111
302–311 95
312–321 97
322–331 97
332–341 99
342–351 96
352–361 69
362–371 76
372–381 71
382–391 71
392–401 62
402–411 54
412–421 41
422–431 63
432–441 53
442–451 31
452–461 42
462–471 40
472–481 29
482–491 34
492–501 30
502–511 23
512–521 41
522–531 29
532–541 28
542–551 16
552–561 18
562–571 18
572–581 17
582–591 17
592–601 17
602–611 19
612–621 13
622–631 12
632–641 11
642–651 16
652–661 9
662–671 5
672–681 13
682–691 12
692–701 6
702–711 6
712–721 9
722–731 9
732–741 6
742–751 11
752–761 10
762–771 7 764
772–781 12
782–791 7
792–801 5
802–806 1
807+ 100
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Hidde L. Ploegh D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Hidde L. Ploegh sits on this spectrum.

No. of scientists
50 100 150 200
Bar chart with 60 bars. Horizontal axis: D-Index, 40–41 to 157+. Vertical axis: number of scientists, 0 to 201. Most scientists, 201, have 58–59 D-Index. The last bar groups every scientist with 157 D-Index or more. The highlighted bar, 157+ D-Index, is where this scientist sits. 40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 163 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40–41 D-Index 157+

This scientist: 163 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

View D-Index distribution as a table
Number of Immunology scientists by D-index, Research.com 2026 ranking edition. Based on 4,929 ranked scientists.
D-Index Scientists This scientist
40–41 28
42–43 91
44–45 157
46–47 192
48–49 175
50–51 188
52–53 177
54–55 155
56–57 194
58–59 201
60–61 197
62–63 201
64–65 173
66–67 167
68–69 172
70–71 199
72–73 184
74–75 133
76–77 163
78–79 127
80–81 121
82–83 125
84–85 121
86–87 102
88–89 96
90–91 75
92–93 72
94–95 74
96–97 66
98–99 68
100–101 49
102–103 60
104–105 54
106–107 36
108–109 23
110–111 52
112–113 41
114–115 34
116–117 25
118–119 28
120–121 11
122–123 20
124–125 27
126–127 19
128–129 20
130–131 16
132–133 17
134–135 14
136–137 15
138–139 9
140–141 11
142–143 9
144–145 9
146–147 7
148–149 7
150–151 7
152–153 5
154–155 8
156 6
157+ 96 163
Download as CSV

Research.com Recognitions

  • 2026 - Research.com Immunology in United States Leader Award
  • 2025 - Research.com Biology and Biochemistry in United States Leader Award
  • 2023 - Research.com Biology and Biochemistry in United States Leader Award
  • 2020 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2019 - National Institutes of Health Director's Pioneer Award
  • 2016 - Member of the National Academy of Sciences
  • 2012 - National Institutes of Health Director's Pioneer Award
  • 2000 - Fellow of the American Academy of Arts and Sciences
  • 1997 - Royal Netherlands Academy of Arts and Sciences
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Hidde L. Ploegh is affiliated with Boston Children's Hospital in the United States. Their scientific work spans multiple disciplines, notably medicine, biochemistry, genetics, molecular biology, immunology, and microbiology. Their research further extends into subfields such as molecular biology, immunology, radiology, nuclear medicine and imaging, infectious diseases, and oncology.

Their primary research topics include monoclonal and polyclonal antibodies research, immunotherapy and immune responses, immune cell function and interaction, T-cell and B-cell immunology, interferon and immune responses, glycosylation and glycoproteins research, and CAR-T cell therapy research.

Frequent coauthors of Hidde L. Ploegh include:

  • Novalia Pishesha
  • Ross W. Cheloha
  • Thibault J. Harmand
  • Mohammad Rashidian
  • Charlotte Wijne

They publish regularly in various scientific venues. The most frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Proceedings of the National Academy of Sciences
  • eLife
  • Nature Communications

Recent publications by Hidde L. Ploegh are:

  • "A guide to antigen processing and presentation", 2022, Nature Reviews. Immunology
  • "Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition", 2020, Cell
  • "Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection", 2021, Nature Immunology
  • "Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections", 2021, Immunity
  • "An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity", 2022, Cell

The scientist has been recognized with several awards including:

  • Distinguished Fellows of the American Association of Immunologists (AAI), 2020
  • National Institutes of Health Director's Pioneer Award, 2019
  • Member of the National Academy of Sciences, 2016
  • National Institutes of Health Director's Pioneer Award, 2012
  • Fellow of the American Academy of Arts and Sciences, 2000
  • Royal Netherlands Academy of Arts and Sciences, 1997
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

    Luke A. Gilbert;Max A. Horlbeck;Britt Adamson;Jacqueline E. Villalta

  • CX3CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance

    Jan Hendrik Niess;Stephan Brand;Xiubin Gu;Limor Landsman

  • Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction.

    Emmanuel J. H. J. Wiertz;Domenico Tortorella;Matthew Bogyo;Joyce Yu

  • The Human Cytomegalovirus US11 Gene Product Dislocates MHC Class I Heavy Chains from the Endoplasmic Reticulum to the Cytosol

    Emmanuel J.H.J Wiertz;Thomas R Jones;Lei Sun;Matthew Bogyo

  • Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

    Takeshi Maruyama;Stephanie K Dougan;Matthias C Truttmann;Angelina M Bilate

  • Empty MHC class I molecules come out in the cold

    H G Ljunggren;N J Stam;C Ohlén;J J Neefjes

  • Herpes simplex virus turns off the TAP to evade host immunity

    Ann Hill;Pieter Jugovic;lan York;Gustav Russ

  • Viral Subversion of the Immune System

    Domenico Tortorella;Benjamin E. Gewurz;Margo H. Furman;Danny J. Schust

  • Viral Strategies of Immune Evasion

    Hidde L. Ploegh

  • The known unknowns of antigen processing and presentation

    Jatin M. Vyas;Annemarthe G. Van der Veen;Hidde L. Ploegh

  • TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells.

    Luc Van Kaer;Luc Van Kaer;Philip G. Ashton-Rickardt;Philip G. Ashton-Rickardt;Hidde L. Ploegh;Susumu Tonegawa;Susumu Tonegawa

  • A membrane protein required for dislocation of misfolded proteins from the ER.

    Brendan N. Lilley;Hidde L. Ploegh

  • A guide to antigen processing and presentation

    Unknown

  • An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration

    Sabrina M Lehmann;Christina Krüger;Boyoun Park;Katja Derkow

  • Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments.

    Peter J. Peters;Jacques J. Neefjes;Viola Oorschot;Hidde L. Ploegh

  • UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

    You-Me Kim;Melanie M. Brinkmann;Marie-Eve Paquet;Hidde L. Ploegh

  • Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus.

    Terry Nakagawa;Wera Roth;Phillip Wong;Andrew Nelson

  • Multiple Associated Proteins Regulate Proteasome Structure and Function

    David S. Leggett;John Hanna;Anna Borodovsky;Bernat Crosas

  • Sortagging: a versatile method for protein labeling

    Maximilian W Popp;John M Antos;Gijsbert M Grotenbreg;Eric Spooner

  • Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.

    Haim Y Cohen;Siva Lavu;Kevin J Bitterman;Brian Hekking

  • Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase.

    Rob A. Gruters;Jacques J. Neefjes;Matthijs Tersmette;Ruud E. Y. de Goede

Frequent Co-Authors

Benedikt M. Kessler
Benedikt M. Kessler University of Oxford
Jacques Neefjes
Jacques Neefjes Leiden University Medical Center
Huib Ovaa
Huib Ovaa Leiden University Medical Center
Ton N. M. Schumacher
Ton N. M. Schumacher Antoni van Leeuwenhoek Hospital
Marianne Boes
Marianne Boes Utrecht University
Matthew Bogyo
Matthew Bogyo Stanford University
Susumu Tonegawa
Susumu Tonegawa MIT
Jan E. Carette
Jan E. Carette Stanford University
Herman S. Overkleeft
Herman S. Overkleeft Leiden University
Thijn R. Brummelkamp
Thijn R. Brummelkamp Antoni van Leeuwenhoek Hospital

External Links

Wikipedia of Hidde L. Ploegh Personal website of Hidde L. Ploegh

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Best Scientists Citing Hidde L. Ploegh

Jacques Neefjes

Jacques Neefjes

Leiden University Medical Center

Publications: 127

Soldano Ferrone

Soldano Ferrone

Harvard University

Publications: 108

Jonathan S. Weissman

Jonathan S. Weissman

MIT

Publications: 107

Huib Ovaa

Huib Ovaa

Leiden University Medical Center

Publications: 102

Herman S. Overkleeft

Herman S. Overkleeft

Leiden University

Publications: 96

Peter Cresswell

Peter Cresswell

Yale University

Publications: 91

Emmanuel J. H. J. Wiertz

Emmanuel J. H. J. Wiertz

Utrecht University

Publications: 87

Robert Tampé

Robert Tampé

Goethe University Frankfurt

Publications: 83

Matthew Bogyo

Matthew Bogyo

Stanford University

Publications: 82

Thijn R. Brummelkamp

Thijn R. Brummelkamp

Antoni van Leeuwenhoek Hospital

Publications: 67

Jeffrey L. Brodsky

Jeffrey L. Brodsky

University of Pittsburgh

Publications: 66

Alfred L. Goldberg

Alfred L. Goldberg

Harvard University

Publications: 62

Thomas Reinheckel

Thomas Reinheckel

University of Freiburg

Publications: 60

Jack L. Strominger

Jack L. Strominger

Harvard University

Publications: 59

J. Christopher Love

J. Christopher Love

MIT

Publications: 59

Keiji Tanaka

Keiji Tanaka

Tokyo Metropolitan Institute of Medical Science

Publications: 57

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