His primary areas of study are Biochemistry, Cell biology, Molecular biology, Ubiquitin and Proteasome. His Cell biology research is multidisciplinary, relying on both Chromatin, Apoptosis and DNA damage, Genome instability. His work in Apoptosis addresses issues such as Ku70, which are connected to fields such as Calorie restriction, PCAF and Acetylation.
His work deals with themes such as Dendritic cell, DNA, DNA repair, Cyclin-dependent kinase complex and Mitochondrion, which intersect with Molecular biology. His Proteases research extends to the thematically linked field of Ubiquitin. His studies in Proteasome integrate themes in fields like Proteolysis, Tripeptidyl peptidase II, Transfection and Peptide.
The scientist’s investigation covers issues in Cell biology, Biochemistry, Ubiquitin, Proteomics and Molecular biology. His research in Cell biology is mostly concerned with Signal transduction. His study in Hydroxylation, Enzyme, Proteases and Cysteine is carried out as part of his studies in Biochemistry.
His Ubiquitin study frequently draws connections between adjacent fields such as Proteasome. His study brings together the fields of Proteome and Proteomics. His study ties his expertise on Histone together with the subject of Chromatin.
Cell biology, Ubiquitin, Group, Deposition and Crystallography are his primary areas of study. The Cell biology study combines topics in areas such as Chromatin, DNA, Proteome and Proteomics. He interconnects Regulation of gene expression, Histone and Epigenetics in the investigation of issues within Chromatin.
Biochemistry covers Benedikt M. Kessler research in Proteomics. His study in Ubiquitin focuses on Deubiquitinating enzyme and Ubiquitin ligase. Benedikt M. Kessler works mostly in the field of Endoplasmic reticulum, limiting it down to topics relating to Innate immune system and, in certain cases, Cytotoxic T cell.
His scientific interests lie mostly in Cell biology, Ubiquitin, Biochemistry, Proteomics and Proteome. Benedikt M. Kessler has included themes like Chromatin, Lipid metabolism and Genome instability in his Cell biology study. His Ubiquitin study integrates concerns from other disciplines, such as SNX27 and PDZ domain.
His study in Biochemistry focuses on Transmembrane protein in particular. His research investigates the connection with Proteomics and areas like Chemical biology which intersect with concerns in Amino acid, Cellular proteins, Protein ubiquitination, Chemoproteomics and Ubiquitin-Specific Proteases. His Proteome research incorporates elements of Sperm, Drosophila melanogaster, Extracellular vesicle and Nanoparticle tracking analysis.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase.
Haim Y. Cohen;Christine Miller;Kevin J. Bitterman;Nathan R. Wall.
Science (2004)
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Evanna L Mills;Dylan G Ryan;Hiran A Prag;Dina Dikovskaya.
Nature (2018)
Broad and strong memory CD4 + and CD8 + T cells induced by SARS-CoV-2 in UK convalescent individuals following COVID-19.
Y Peng;A J Mentzer;G Liu;G Liu;X Yao.
Nature Immunology (2020)
Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis.
Haim Y Cohen;Siva Lavu;Kevin J Bitterman;Brian Hekking.
Molecular Cell (2004)
Variant PRC1 Complex-Dependent H2A Ubiquitylation Drives PRC2 Recruitment and Polycomb Domain Formation
Neil P. Blackledge;Anca M. Farcas;Takashi Kondo;Hamish W. King.
Cell (2014)
Chemistry-Based Functional Proteomics Reveals Novel Members of the Deubiquitinating Enzyme Family
Anna Borodovsky;Huib Ovaa;Nagamalleswari Kolli;Tudeviin Gan-Erdene.
Chemistry & Biology (2002)
A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14.
Anna Borodovsky;Benedikt M. Kessler;Rocco Casagrande;Herman S. Overkleeft.
The EMBO Journal (2001)
Renal Cyst Formation in Fh1-Deficient Mice Is Independent of the Hif/Phd Pathway: Roles for Fumarate in KEAP1 Succination and Nrf2 Signaling
Julie Adam;Emine Hatipoglu;Linda O'Flaherty;Nicola Ternette.
Cancer Cell (2011)
A Small Molecule Inhibitor of Ubiquitin-Specific Protease-7 Induces Apoptosis in Multiple Myeloma Cells and Overcomes Bortezomib Resistance
Dharminder Chauhan;Ze Tian;Benjamin Nicholson;K.G. Suresh Kumar.
Cancer Cell (2012)
Arginine methylation regulates the p53 response
Martin Jansson;Stephen T. Durant;Er Chieh Cho;Sharon Sheahan.
Nature Cell Biology (2008)
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