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Peter J. Ratcliffe
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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
139
Citations
98292
World Ranking
279
National Ranking
17

Medicine

D-Index
139
Citations
98583
World Ranking
1722
National Ranking
176

Peter J. Ratcliffe publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Peter J. Ratcliffe sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 442 publications — 92nd percentile

92% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Peter J. Ratcliffe D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Peter J. Ratcliffe sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 139 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2019 - Nobel Prize for their discoveries of how cells sense and adapt to oxygen availability
  • 2017 - Buchanan Medal, Royal Society (UK) for his ground-breaking research on oxygen sensing and signalling pathways mediating cellular responses to hypoxia".
  • 2016 - Albert Lasker Award for Basic Medical Research, Lasker Foundation
  • 2012 - Robert J. and Claire Pasarow Foundation Medical Research Award
  • 2010 - Canada Gairdner International Award
  • 2007 - Fellow of the American Academy of Arts and Sciences
  • 2002 - Fellow of the Royal Society, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the Association of American Physicians
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Peter J. Ratcliffe is primarily affiliated with The Francis Crick Institute in the United Kingdom. Their research focuses on cellular responses to oxygen availability, with a significant emphasis on hypoxia and its role in various biological processes, including cancer, immunity, and metabolism.

Their work spans multiple fields of study, notably:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these, they have contributed extensively to several subfields:

  • Cancer Research
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Immunology
  • Genetics

The main topics of Ratcliffe's research include:

  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • High Altitude and Hypoxia
  • Renal cell carcinoma treatment
  • Mitochondrial Function and Pathology
  • Immune cells in cancer

Ratcliffe has published frequently in several key scientific venues. The most frequent include:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Reports
  • Proceedings of the National Academy of Sciences
  • Circulation Research

Their recent papers demonstrate the scope and focus of their research:

  • "Hypoxic and pharmacological activation of HIF inhibits SARS-CoV-2 infection of lung epithelial cells," 2021, Cell Reports
  • "The HIF complex recruits the histone methyltransferase SET1B to activate specific hypoxia-inducible genes," 2021, Nature Genetics
  • "Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation," 2022, Nature Immunology
  • "Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory control," 2020, Journal of Clinical Investigation
  • "A global view of the aspiring physician-scientist," 2022, eLife

Frequent collaborators in Ratcliffe's research include:

  • David R. Mole
  • Joanna D.C.C. Lima
  • Christopher W. Pugh
  • Samvid Kurlekar
  • Thomas P. Keeley

Ratcliffe has been recognized with several awards throughout their career:

  • Nobel Prize, 2019, for discoveries of how cells sense and adapt to oxygen availability
  • Buchanan Medal, Royal Society (UK), 2017, for research on oxygen sensing and signalling pathways mediating cellular responses to hypoxia
  • Albert Lasker Award for Basic Medical Research, 2016
  • Robert J. and Claire Pasarow Foundation Medical Research Award, 2012
  • Canada Gairdner International Award, 2010
  • Fellow of the American Academy of Arts and Sciences, 2007
  • Fellow of the Royal Society, United Kingdom, 2002
  • Member of the Association of American Physicians
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • Targeting of HIF-alpha to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation

    Panu Jaakkola;David R. Mole;Ya-Min Tian;Michael I. Wilson

  • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

    Patrick H. Maxwell;Michael S. Wiesener;Gin-Wen Chang;Steven C. Clifford

  • C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.

    Andrew C.R. Epstein;Jonathan M. Gleadle;Luke A. McNeill;Kirsty S. Hewitson

  • Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

    William G. Kaelin;Peter J. Ratcliffe

  • Regulation of angiogenesis by hypoxia: role of the HIF system.

    Christopher W Pugh;Peter J Ratcliffe

  • Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis.

    Peter Carmeliet;Yuval Dor;Jean-Marc Herbert;Dai Fukumura

  • Oxygen sensing by HIF hydroxylases

    Christopher J. Schofield;Peter J. Ratcliffe

  • The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages

    Katherine L. Talks;Helen Turley;Kevin C. Gatter;Patrick H. Maxwell

  • Hypoxia-inducible Expression of Tumor-associated Carbonic Anhydrases

    Charles C. Wykoff;Nigel J. P. Beasley;Peter H. Watson;Kevin J. Turner

  • Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

    P H Maxwell;G U Dachs;J M Gleadle;L G Nicholls

  • Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein.

    Matthew E. Cockman;Norma Masson;David R. Mole;Panu Jaakkola

  • Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation

    Norma Masson;Carsten Willam;Patrick H. Maxwell;Christopher W. Pugh

  • Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor *

    Rebecca J. Appelhoff;Ya-Min Tian;Raju R. Raval;Helen Turley

  • HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability

    Jennifer S. Isaacs;Yun Jin Jung;David R. Mole;Sunmin Lee

  • The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases

    Rasheduzzaman Chowdhury;Kar Kheng Yeoh;Ya-Min Tian;Lars Hillringhaus

  • Contrasting Properties of Hypoxia-Inducible Factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-Associated Renal Cell Carcinoma

    Raju R. Raval;Kah Weng Lau;Maxine G. B. Tran;Heidi M. Sowter

  • Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

    Michael S Wiesener;Jan Steffen Jürgensen;Christian Rosenberger;Charlotte K Scholze

  • Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

    Massimiliano Mazzone;Massimiliano Mazzone;Daniela Dettori;Daniela Dettori;Daniela Dettori;Rodrigo Leite de Oliveira;Rodrigo Leite de Oliveira;Sonja Loges;Sonja Loges

  • Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family

    Kirsty S. Hewitson;Luke A. McNeill;Madeline V. Riordan;Ya-Min Tian

  • HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors.

    Heidi M. Sowter;Peter J. Ratcliffe;Peter Watson;Arnold H. Greenberg

Frequent Co-Authors

Christopher W. Pugh
Christopher W. Pugh University of Oxford
Christopher J. Schofield
Christopher J. Schofield University of Oxford
Patrick H. Maxwell
Patrick H. Maxwell University of Cambridge
adrian l harris
adrian l harris University of Oxford
Benedikt M. Kessler
Benedikt M. Kessler University of Oxford
Kai-Uwe Eckardt
Kai-Uwe Eckardt Charité - University Medicine Berlin
Michael A. McDonough
Michael A. McDonough University of Oxford
Peter Carmeliet
Peter Carmeliet KU Leuven
Benjamin L. Ebert
Benjamin L. Ebert Harvard University
Martin Farrall
Martin Farrall University of Oxford

External Links

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