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Biology and Biochemistry
Switzerland
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
96
Citations
34414
World Ranking
1817
National Ranking
41

Medicine

D-Index
96
Citations
34707
World Ranking
9640
National Ranking
129

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Switzerland Leader Award

Overview

Max Gassmann is affiliated with the University of Zurich in Switzerland. Their research spans multiple interconnected areas within medicine and the life sciences, with a particular focus on hypoxia-related mechanisms, iron metabolism, and hematology.

The scientist's work is principally categorized within the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Subfields include Genetics, Hematology, Cancer Research, Physiology, and Molecular Biology. This interdisciplinary approach reflects the diversity of their research themes and methodologies.

Key topics frequently addressed in Gassmann's work include:

  • Cancer, Hypoxia, and Metabolism
  • High Altitude and Hypoxia
  • Hemoglobinopathies and Related Disorders
  • Iron Metabolism and Disorders
  • Erythropoietin and Anemia Treatment
  • Neuroscience of Respiration and Sleep
  • Adipose Tissue and Metabolism

Significant recent publications by Max Gassmann highlight various aspects of hypoxia and its physiological or pathophysiological impacts:

  • "Maternal Iron Status in Pregnancy and Child Health Outcomes after Birth: A Systematic Review and Meta-Analysis" (2021) published in Nutrients
  • "Pericyte hypoxia-inducible factor-1 (HIF-1) drives blood-brain barrier disruption and impacts acute ischemic stroke outcome" (2021) published in Angiogenesis
  • "Mechanisms underlying the health benefits of intermittent hypoxia conditioning" (2023) published in The Journal of Physiology
  • "The Brain at High Altitude: From Molecular Signaling to Cognitive Performance" (2023) published in International Journal of Molecular Sciences
  • "Hypoxia-induced pulmonary hypertension-Utilizing experiments of nature" (2020) published in British Journal of Pharmacology

Gassmann frequently collaborates with several researchers, including:

  • Mostafa A. Aboouf
  • Markus Thiersch
  • Julia Armbruster
  • Thomas A. Gorr
  • Martina U. Muckenthaler

Their work appears regularly in a variety of scientific journals, with multiple publications in venues such as HemaSphere, Cells, Frontiers in Physiology, PLoS ONE, and Scientific Reports. This spread across journals demonstrates engagement with diverse scientific audiences.

Best Publications

  • Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α

    Narayan V. Iyer;Lori E. Kotch;Faton Agani;Sandra W. Leung

  • Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth

    Heather E. Ryan;Michelle Poloni;Wayne McNulty;David Elson

  • Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells

    Helga Ellingsgaard;Irina Hauselmann;Beat Schuler;Abdella M Habib

  • HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia

    Deborah M. Stroka;Tobias Burkhardt;Isabelle Desbaillets;Roland H. Wenger

  • Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFβ3

    Isabella Caniggia;Homa Mostachfi;Jennifer Winter;Max Gassmann

  • HIF-1-induced erythropoietin in the hypoxic retina protects against light-induced retinal degeneration

    Christian Grimm;Andreas Wenzel;Matthias Groszer;Helmut Mayser

  • Induction of HIF-1alpha in response to hypoxia is instantaneous.

    Ursula R. Jewell;Ivica Kvietikova;Annette Scheid;Christian Bauer

  • OXYGEN(ES) AND THE HYPOXIA-INDUCIBLE FACTOR-1

    Wenger Rh;Gassmann M

  • Erythropoietin gene expression in human, monkey and murine brain.

    H H Marti;R H Wenger;L A Rivas;U Straumann

  • Localization of specific erythropoietin binding sites in defined areas of the mouse brain.

    Murat Digicaylioglu;Sandrine Bichet;Hugo H. Marti;Roland H. Wenger

  • Quantifying Western blots: pitfalls of densitometry.

    Max Gassmann;Beat Grenacher;Bianca Rohde;Johannes Vogel

  • Efficient production of chicken egg yolk antibodies against a conserved mammalian protein.

    Max Gassmann;Pia Thömmes;Thomas Weiser;Ulrich Hübscher

  • Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor.

    K Gradin;J McGuire;R H Wenger;I Kvietikova

  • Oxygen-regulated Transferrin Expression Is Mediated by Hypoxia-inducible Factor-1

    Andreas Rolfs;Ivica Kvietikova;Max Gassmann;Roland H. Wenger

  • Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species

    Maria Wartenberg;Frederike C. Ling;Markus Müschen;Florian Klein

  • Embryoid bodies: an in vitro model of mouse embryogenesis.

    Isabelle Desbaillets;Urs Ziegler;Peter Groscurth;Max Gassmann

  • Uncontrolled Expression of Vascular Endothelial Growth Factor and Its Receptors Leads to Insufficient Skin Angiogenesis in Patients With Systemic Sclerosis

    Oliver Distler;Jörg H. W. Distler;Annette Scheid;Till Acker

  • Defective Brain Development in Mice Lacking the Hif-1α Gene in Neural Cells

    Shuhei Tomita;Masaki Ueno;Masami Sakamoto;Yuki Kitahama

  • Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis.

    Mercedes Garayoa;Alfredo Martínez;Sunmin Lee;Rubén Pío

  • Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin.

    Frank T. Ruschitzka;Roland H. Wenger;Thomas Stallmach;Thomas Quaschning

Frequent Co-Authors

Roland H. Wenger
Roland H. Wenger University of Zurich
Martina U. Muckenthaler
Martina U. Muckenthaler Heidelberg University
Joachim Fandrey
Joachim Fandrey University of Duisburg-Essen
Ulrich Hübscher
Ulrich Hübscher University of Zurich
Christian Grimm
Christian Grimm University of Zurich
Andreas Wenzel
Andreas Wenzel Novartis (Switzerland)
Thomas A. Lutz
Thomas A. Lutz University of Zurich
Dirk M. Hermann
Dirk M. Hermann University of Duisburg-Essen
Ertugrul Kilic
Ertugrul Kilic Istanbul Medipol University
Charlotte E. Remé
Charlotte E. Remé University of Zurich

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