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Thomas Kietzmann

Thomas Kietzmann

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
17200
World Ranking
9068
National Ranking
66

Overview

Thomas Kietzmann is affiliated with the University of Oulu in Finland and has a research portfolio focused on molecular biology and biochemistry, with intersections in medicine. Their work significantly spans areas including cancer research, immunology, physiology, and epidemiology.

Their research topics include:

  • Ubiquitin and proteasome pathways
  • Cancer, hypoxia, and metabolism
  • RNA modifications and cancer
  • Endoplasmic reticulum stress and disease
  • Immune cell function and interaction
  • Autophagy in disease and therapy
  • Adipose tissue and metabolism

Kietzmann has coauthored extensively with several researchers, including Daniela Mennerich, Elitsa Y. Dimova, Kateryna Kubaichuk, Margit Egg, and Adam Albanese.

They have published frequently in journals such as Redox Biology, bioRxiv (Cold Spring Harbor Laboratory), International Journal of Molecular Sciences, Frontiers in Psychiatry, and Preprints.org.

Key recent publications include:

  • "The Role of Hypoxia-Inducible Factor Post-Translational Modifications in Regulating Its Localisation, Stability, and Activity," 2020, International Journal of Molecular Sciences
  • "The glyco-redox interplay: Principles and consequences on the role of reactive oxygen species during protein glycosylation," 2021, Redox Biology
  • "A pan-cancer analysis shows immunoevasive characteristics in NRF2 hyperactive squamous malignancies," 2023, Redox Biology
  • "Vitamin C: From nutrition to oxygen sensing and epigenetics," 2023, Redox Biology
  • "Analysis of GWAS-Derived Schizophrenia Genes for Links to Ischemia-Hypoxia Response of the Brain," 2020, Frontiers in Psychiatry

Best Publications

  • Antioxidant responses and cellular adjustments to oxidative stress.

    Cristina Espinosa-Diez;Verónica Miguel;Daniela Mennerich;Thomas Kietzmann

  • The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control.

    Agnes Görlach;Peter Klappa;Thomas Kietzmann

  • Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site.

    Steve Bonello;Christian Zähringer;Rachida S. BelAiba;Talija Djordjevic

  • ZONATION OF PARENCHYMAL AND NONPARENCHYMAL METABOLISM IN LIVER

    Kurt Jungermann;Thomas Kietzmann

  • Hypoxia Up-Regulates Hypoxia-Inducible Factor-1α Transcription by Involving Phosphatidylinositol 3-Kinase and Nuclear Factor κB in Pulmonary Artery Smooth Muscle Cells

    Rachida S. BelAiba;Steve Bonello;Christian Zähringer;Stefanie Schmidt

  • Oxygen: modulator of metabolic zonation and disease of the liver.

    Kurt Jungermann;Thomas Kietzmann

  • Thrombin activates the hypoxia-inducible factor-1 signaling pathway in vascular smooth muscle cells: Role of the p22(phox)-containing NADPH oxidase.

    A. Görlach;I. Diebold;V. B. Schini-Kerth;U. Berchner-Pfannschmidt

  • Metabolic zonation of the liver: The oxygen gradient revisited.

    Thomas Kietzmann

  • Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression

    Thomas Kietzmann;Agnes Görlach

  • Reactive oxygen species, nutrition, hypoxia and diseases: Problems solved?

    Agnes Görlach;Elitsa Y. Dimova;Andreas Petry;Antonio Martínez-Ruiz

  • Induction of the Plasminogen Activator Inhibitor-1 Gene Expression by Mild Hypoxia Via a Hypoxia Response Element Binding the Hypoxia-Inducible Factor-1 in Rat Hepatocytes

    Thomas Kietzmann;Ulrike Roth;Kurt Jungermann

  • NOX2 and NOX4 mediate proliferative response in endothelial cells.

    Andreas Petry;Talija Djordjevic;Michael Weitnauer;Thomas Kietzmann

  • European contribution to the study of ROS : a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

    Javier Egea;Isabel Fabregat;Yves M Frapart;Pietro Ghezzi

  • Reactive oxygen species and fibrosis: further evidence of a significant liaison

    Kati Richter;Thomas Kietzmann

  • Glycogen Synthase Kinase 3 Phosphorylates Hypoxia-Inducible Factor 1α and Mediates Its Destabilization in a VHL-Independent Manner

    Daniela Flügel;Agnes Görlach;Carine Michiels;Thomas Kietzmann

  • Regulation of the Hypoxia-inducible Factor 1α by the Inflammatory Mediators Nitric Oxide and Tumor Necrosis Factor-α in Contrast to Desferroxamine and Phenylarsine Oxide

    Katrin B. Sandau;Jie Zhou;Thomas Kietzmann;Bernhard Brüne

  • Redox-fibrosis: Impact of TGFβ1 on ROS generators, mediators and functional consequences.

    Kati Richter;Anja Konzack;Taina Pihlajaniemi;Ritva Heljasvaara

  • A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression

    Qing Liu;Utta Berchner-Pfannschmidt;Ulrike Möller;Martina Brecht

  • Transcriptional Regulation of Heme Oxygenase-1 Gene Expression by MAP Kinases of the JNK and p38 Pathways in Primary Cultures of Rat Hepatocytes *

    Thomas Kietzmann;Anatoly Samoylenko;Stephan Immenschuh

  • GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α.

    Daniela Flügel;Agnes Görlach;Thomas Kietzmann

Frequent Co-Authors

Hartmut Kühn
Hartmut Kühn Charité - University Medicine Berlin
Kurt Jungermann
Kurt Jungermann University of Göttingen
Agnes Görlach
Agnes Görlach Technical University of Munich
John Hess
John Hess Ludwig-Maximilians-Universität München
Joachim Fandrey
Joachim Fandrey University of Duisburg-Essen
Giuliano Ramadori
Giuliano Ramadori University of Göttingen
Terry G. Unterman
Terry G. Unterman University of Illinois at Chicago
John R. Hess
John R. Hess University of Washington
Martin Wabitsch
Martin Wabitsch University of Ulm
Jim van Os
Jim van Os University Medical Center Utrecht

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