Terry G. Unterman spends much of his time researching FOXO1, Transcription factor, Protein kinase B, Molecular biology and Phosphorylation. His FOXO1 research is multidisciplinary, incorporating perspectives in Glycolysis, Cancer research, Gluconeogenesis and Glycerol transport. His work in the fields of Transcription factor, such as Forkhead Transcription Factors, intersects with other areas such as Fas ligand.
His biological study spans a wide range of topics, including Endocrinology, Cell aging and Insulin receptor substrate. The study incorporates disciplines such as Nuclear localization sequence, Insulin and DNA-binding protein in addition to Phosphorylation. His study in Cell biology is interdisciplinary in nature, drawing from both Cancer cell and Oxidative stress.
Terry G. Unterman mainly focuses on Endocrinology, Internal medicine, FOXO1, Insulin and Molecular biology. His Endocrinology study incorporates themes from Growth factor and Insulin-like growth factor. Much of his study explores Internal medicine relationship to Fetus.
A component of his FOXO1 study involves Transcription factor, Cell biology, Phosphorylation and Protein kinase B. Terry G. Unterman usually deals with Phosphorylation and limits it to topics linked to Transactivation and Proto-Oncogene Proteins c-akt. His Molecular biology research also works with subjects such as
Internal medicine, Endocrinology, Insulin resistance, Insulin and FOXO1 are his primary areas of study. Terry G. Unterman combines subjects such as Diabetes mellitus and Type 2 diabetes with his study of Internal medicine. His Vasodilation, Hyperinsulinism, Vasoconstriction and Skeletal muscle study in the realm of Endocrinology connects with subjects such as Enos.
His Insulin research is multidisciplinary, incorporating elements of Glycolysis, Beta oxidation and Gluconeogenesis. The various areas that Terry G. Unterman examines in his FOXO1 study include Gene expression and Genetically modified organism. His work on PI3K/AKT/mTOR pathway as part of his general Cell biology study is frequently connected to Sirtuin, thereby bridging the divide between different branches of science.
Terry G. Unterman spends much of his time researching Internal medicine, Endocrinology, Macrophage, Adipose tissue and Lipid metabolism. His Internal medicine research incorporates themes from Diabetes mellitus and Type 2 diabetes. His Endocrinology study frequently draws connections to other fields, such as Hormone receptor.
His Adipose tissue study integrates concerns from other disciplines, such as Glycolysis, Beta oxidation, Carbohydrate metabolism and Gluconeogenesis. Terry G. Unterman combines subjects such as FOXO1 and Macrophage-activating factor with his study of Immunology. His Hyperinsulinism study in the realm of Insulin interacts with subjects such as Enos.
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Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues
Xinmin Zhang;Duncan T. Odom;Seung Hoi Koo;Michael D. Conkright.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B.
Graham Rena;Shaodong Guo;Stephen C. Cichy;Terry G. Unterman.
Journal of Biological Chemistry (1999)
Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence.
Shaodong Guo;Graham Rena;Stephen Cichy;Xiaowei He.
Journal of Biological Chemistry (1999)
Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis.
Veronique Nogueira;Youngkyu Park;Chia Chen Chen;Pei Zhang Xu.
Cancer Cell (2008)
FoxO proteins in insulin action and metabolism
Andreas Barthel;Dieter Schmoll;Terry G. Unterman.
Trends in Endocrinology and Metabolism (2005)
FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression
Wenwei Zhang;Sandip Patil;Sandip Patil;Balwant Chauhan;Balwant Chauhan;Shaodong Guo;Shaodong Guo.
Journal of Biological Chemistry (2006)
Regulation of Glucose-6-phosphatase Gene Expression by Protein Kinase Bα and the Forkhead Transcription Factor FKHR EVIDENCE FOR INSULIN RESPONSE UNIT-DEPENDENT AND -INDEPENDENT EFFECTS OF INSULIN ON PROMOTER ACTIVITY
Dieter Schmoll;Kay S. Walker;Dario R. Alessi;Rolf Grempler.
Journal of Biological Chemistry (2000)
Phosphorylation of Serine 256 Suppresses Transactivation by FKHR (FOXO1) by Multiple Mechanisms DIRECT AND INDIRECT EFFECTS ON NUCLEAR/CYTOPLASMIC SHUTTLING AND DNA BINDING
Xiaohui Zhang;Lixia Gan;Haiyun Pan;Shaodong Guo.
Journal of Biological Chemistry (2002)
Hepatic insulin resistance directly promotes formation of cholesterol gallstones.
Sudha B Biddinger;Sudha B Biddinger;Joel T Haas;Bian B Yu;Olivier Bezy.
Nature Medicine (2008)
Intermittent fasting vs daily calorie restriction for type 2 diabetes prevention: a review of human findings
Adrienne R. Barnosky;Kristin K. Hoddy;Terry G. Unterman;Kristina A. Varady.
Translational Research (2014)
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