Shaodong Guo

Overview

Best Publications

• Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

  Graham Rena;Shaodong Guo;Stephen C. Cichy;Terry G. Unterman

  936
  Citations

• Phosphorylation of serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter activity through a conserved insulin response sequence.

  Shaodong Guo;Graham Rena;Stephen Cichy;Xiaowei He

  777
  Citations

• FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression

  Wenwei Zhang;Sandip Patil;Sandip Patil;Balwant Chauhan;Balwant Chauhan;Shaodong Guo;Shaodong Guo

  615
  Citations

• Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation

  Xiaocheng C. Dong;Kyle D. Copps;Shaodong Guo;Yedan Li

  496
  Citations

• Regulation of Glucose-6-phosphatase Gene Expression by Protein Kinase Bα and the Forkhead Transcription Factor FKHR EVIDENCE FOR INSULIN RESPONSE UNIT-DEPENDENT AND -INDEPENDENT EFFECTS OF INSULIN ON PROMOTER ACTIVITY

  Dieter Schmoll;Kay S. Walker;Dario R. Alessi;Rolf Grempler

  485
  Citations

• Phosphorylation of Serine 256 Suppresses Transactivation by FKHR (FOXO1) by Multiple Mechanisms DIRECT AND INDIRECT EFFECTS ON NUCLEAR/CYTOPLASMIC SHUTTLING AND DNA BINDING

  Xiaohui Zhang;Lixia Gan;Haiyun Pan;Shaodong Guo

  372
  Citations

• Foxo1 integrates insulin signaling with mitochondrial function in the liver

  Zhiyong Cheng;Shaodong Guo;Kyle Copps;Xiaochen Dong;Xiaochen Dong

  341
  Citations

• The kinase DYRK1A phosphorylates the transcription factor FKHR at Ser329 in vitro, a novel in vivo phosphorylation site.

  Yvonne L. Woods;Graham Rena;Nick Morrice;Andreas Barthel

  331
  Citations

• Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting.

  Graham Rena;Alan R. Prescott;Shaodong Guo;Philip Cohen

  324
  Citations

• Decoding insulin resistance and metabolic syndrome for promising therapeutic intervention.

  Shaodong Guo

  312
  Citations

• Estrogen Improves Insulin Sensitivity and Suppresses Gluconeogenesis via the Transcription Factor Foxo1

  Hui Yan;Wangbao Yang;Fenghua Zhou;Xiaopeng Li

  310
  Citations

• Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK

  Yu Wang;Hongying An;Ting Liu;Caolitao Qin

  304
  Citations

• Vascular Endothelial Growth Factor Activates PI3K/Akt/Forkhead Signaling in Endothelial Cells

  Md. Ruhul Abid;Shaodong Guo;Takashi Minami;Katherine C. Spokes

  297
  Citations

• Etiology of Metabolic Syndrome and Dietary Intervention.

  Hang Xu;Xiaopeng Li;Xiaopeng Li;Hannah Adams;Karen Kubena

  222
  Citations

• Protein kinase B/Akt mediates effects of insulin on hepatic insulin-like growth factor-binding protein-1 gene expression through a conserved insulin response sequence.

  Stephen B. Cichy;Shahab Uddin;Alexey Danilkovich;Shaodong Guo

  211
  Citations

• AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR.

  Pengfei Li;Heehyoung Lee;Shaodong Guo;Terry G. Unterman

  193
  Citations

• Hepatic suppression of Foxo1 and Foxo3 causes hypoglycemia and hyperlipidemia in mice.

  Kebin Zhang;Ling Li;Yajuan Qi;Xiaoping Zhu

  187
  Citations

• The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis.

  Shaodong Guo;Kyle D. Copps;Xiaocheng Dong;Sunmin Park

  163
  Citations

• Forkhead Transcription Factors Inhibit Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia

  Md. Ruhul Abid;Kiichiro Yano;Shaodong Guo;Virendra I. Patel

  160
  Citations

• Insulin Signaling, Resistance, and the Metabolic Syndrome: Insights

  Shaodong Guo

  7
  Citations