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Dario R. Alessi
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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
162
Citations
108187
World Ranking
112
National Ranking
5

Dario R. Alessi publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Dario R. Alessi sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 391 publications — 89th percentile

89% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Dario R. Alessi D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Dario R. Alessi sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 162 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2022 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2008 - Fellow of the Royal Society, United Kingdom
  • 2002 - Fellow of the Royal Society of Edinburgh
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

Dario R. Alessi is affiliated with the University of Dundee in the United Kingdom. Their research spans a broad range of topics primarily within biochemistry, genetics, molecular biology, and medicine, with a significant focus on molecular biology, neurology, and cell biology. Alessi's work contributes to understanding mechanisms related to Parkinson's disease as well as cellular transport and secretion processes.

The main fields of study for Alessi include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of study where Alessi has contributed include:

  • Molecular Biology
  • Neurology
  • Cell Biology
  • Physiology
  • Genetics

The primary topics of research covered by Alessi are:

  • Cellular transport and secretion
  • Parkinson's Disease Mechanisms and Treatments
  • Lysosomal Storage Disorders Research
  • Ubiquitin and proteasome pathways
  • Calcium signaling and nucleotide metabolism
  • Neurological diseases and metabolism
  • Microtubule and mitosis dynamics

Frequent co-authors include:

  • Francesca Tonelli
  • Raja Sekhar Nirujogi
  • Paweł Lis
  • Esther Sammler
  • Suzanne R. Pfeffer

Alessi has published regularly in a variety of scientific venues, with notable frequency in the following journals and repositories:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Biochemical Journal
  • The Cambridge Structural Database
  • Proceedings of the National Academy of Sciences

Significant recent papers authored or co-authored by Alessi include:

  • "A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research," 2021, PLoS Biology
  • "Discovery of XL01126: A Potent, Fast, Cooperative, Selective, Orally Bioavailable, and Blood-Brain Barrier Penetrant PROTAC Degrader of Leucine-Rich Repeat Kinase 2," 2022, Journal of the American Chemical Society
  • "Advances in elucidating the function of leucine-rich repeat protein kinase-2 in normal cells and Parkinson's disease," 2020, Current Opinion in Cell Biology
  • "Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding," 2022, Biochemical Journal
  • "Development of BromoTag: A "Bump-and-Hole"-PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins," 2021, Journal of Medicinal Chemistry

Alessi has been recognized by several professional organizations and has received multiple honors, including:

  • Fellow of the Royal Society, United Kingdom (2008)
  • Fellow of the Royal Society of Edinburgh (2002)
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom

Best Publications

  • Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B.

    Darren A. E. Cross;Dario R. Alessi;Philip Cohen;Mirjana Andjelkovich

  • PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

    Dario R. Alessi;Ana Cuenda;Philip Cohen;David T. Dudley

  • Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

    Dario R. Alessi;Stephen R. James;C.Peter Downes;Andrew B. Holmes

  • Mechanism of activation of protein kinase B by insulin and IGF-1.

    Dario R. Alessi;Mirjana Andjelkovic;Barry Caudwell;Peter Cron

  • The selectivity of protein kinase inhibitors: a further update.

    Jenny Bain;Lorna Plater;Matt Elliott;Natalia Shpiro

  • Metformin and reduced risk of cancer in diabetic patients

    Josie M M Evans;Louise A Donnelly;Alistair M Emslie-Smith;Dario R Alessi

  • The PI3K-PDK1 connection: more than just a road to PKB.

    Bart Vanhaesebroeck;Dario R. Alessi

  • Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

    Simon A Hawley;Jérôme Boudeau;Jennifer L Reid;Kirsty J Mustard

  • LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

    Jose M Lizcano;Olga Göransson;Rachel Toth;Maria Deak

  • The nuts and bolts of AGC protein kinases

    Laura R. Pearce;David Komander;Dario R. Alessi

  • PKB/Akt: a key mediator of cell proliferation, survival and insulin responses?

    Margaret A. Lawlor;Dario R. Alessi

  • Protein Kinase C Isotypes Controlled by Phosphoinositide 3-Kinase Through the Protein Kinase PDK1

    J. Ann Le Good;Wolfgang H. Ziegler;Davey B. Parekh;Dario R. Alessi

  • Role of Translocation in the Activation and Function of Protein Kinase B

    Mirjana Andjelkovic;Dario R. Alessi;Roger Meier;Anne Fernandez

  • Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.

    Barbara T. Navé;D. Margriet Ouwens;Dominic J. Withers;Dario R. Alessi

  • New Users of Metformin Are at Low Risk of Incident Cancer: A cohort study among people with type 2 diabetes

    Gillian Libby;Louise A. Donnelly;Peter T. Donnan;Dario R. Alessi;Dario R. Alessi

  • Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

    Maria Deak;Andrew D. Clifton;John M. Lucocq;Dario R. Alessi

  • mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

    Juan Manuel García-Martínez;Dario R Alessi

  • Mechanism of activation and function of protein kinase B.

    Dario R Alessi;Philip Cohen

  • PDK1, the master regulator of AGC kinase signal transduction.

    Alfonso Mora;David Komander;Daan M.F. van Aalten;Dario R. Alessi

  • 3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

    Dario R. Alessi;Maria Deak;Antonio Casamayor;F. Barry Caudwell

Frequent Co-Authors

Maria Deak
Maria Deak University of Dundee
Philip Cohen
Philip Cohen University of Dundee
Alan R. Prescott
Alan R. Prescott University of Dundee
Daan M. F. van Aalten
Daan M. F. van Aalten University of Dundee
David Komander
David Komander Walter and Eliza Hall Institute of Medical Research
Kei Sakamoto
Kei Sakamoto University of Copenhagen
Paul Davies
Paul Davies Tufts University
Nathanael S. Gray
Nathanael S. Gray Stanford University
Matthias Trost
Matthias Trost Newcastle University
Axel Knebel
Axel Knebel University of Dundee

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Marc Foretz

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James R. Woodgett

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D. Grahame Hardie

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