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Molecular Biology

D-Index
47
Citations
8793
World Ranking
2742
National Ranking
214

Overview

Matthias Trost is affiliated with Newcastle University in the United Kingdom. Their research primarily spans the fields of Biochemistry, Genetics, and Molecular Biology, with a total of 89 publications, alongside Medicine, contributing 67 publications. This scientist's work delves deeply into subfields such as Molecular Biology, Immunology, Epidemiology, Spectroscopy, and Infectious Diseases.

The main topics explored by Matthias Trost include immune cells in cancer, ubiquitin and proteasome pathways, cellular transport and secretion, advanced proteomics techniques and applications, liver disease diagnosis and treatment, autophagy in disease and therapy, and mass spectrometry techniques and applications.

Matthias Trost has authored several research papers, including the following significant publications:

  • Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease, 2021, Journal of Hepatology
  • USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation, 2020, Life Science Alliance
  • Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2, 2021, Nature Communications
  • Advances in high-throughput mass spectrometry in drug discovery, 2022, EMBO Molecular Medicine
  • The role of macrophage scavenger receptor 1 (MSR1) in inflammatory disorders and cancer, 2022, Frontiers in Immunology

Frequent co-authors collaborating with Matthias Trost include Tiaan Heunis, José Luis Marín-Rubio, Andrew M. Frey, María Emilia Dueñas, and Julien Peltier. The most common publication venues for their work reflect a range of biomedical and molecular biology fields:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Journal of Hepatology
  • Zenodo (CERN European Organization for Nuclear Research)
  • Life Science Alliance

Best Publications

  • Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

    Martin Steger;Francesca Tonelli;Genta Ito;Paul Davies

  • Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65.

    Agne Kazlauskaite;Chandana Kondapalli;Robert Gourlay;David G. Campbell

  • USP7 small-molecule inhibitors interfere with ubiquitin binding

    Lorna Kategaya;Paola Di Lello;Lionel Rougé;Richard Pastor

  • UBQLN2 mediates autophagy-independent protein aggregate clearance by the proteasome

    Roland Hjerpe;John S. Bett;John S. Bett;Matthew J. Keuss;Alexandra Solovyova

  • The Phagosomal Proteome in Interferon-γ-Activated Macrophages

    Matthias Trost;Luc English;Sébastien Lemieux;Mathieu Courcelles

  • Patterns, Receptors, and Signals: Regulation of Phagosome Maturation

    Anne-Marie Pauwels;Matthias Trost;Rudi Beyaert;Eik Hoffmann;Eik Hoffmann

  • Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

    Agne Kazlauskaite;R. Julio Martinez-Torres;Scott Wilkie;Atul Kumar

  • Comparative proteome analysis of secretory proteins from pathogenic and nonpathogenic Listeria species.

    Matthias Trost;Dirk Wehmhöner;Uwe Kärst;Guido Dieterich

  • The type VI secretion system deploys antifungal effectors against microbial competitors.

    Katharina Trunk;Julien Peltier;Julien Peltier;Yi-Chia Liu;Brian D. Dill

  • VgrG and PAAR Proteins Define Distinct Versions of a Functional Type VI Secretion System

    Francesca R. Cianfanelli;Juliana Alcoforado Diniz;Manman Guo;Virginia De Cesare

  • Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

    Yu Chiang Lai;Chandana Kondapalli;Ronny Lehneck;James B. Procter

  • Molecular characterization of the evolution of phagosomes

    Jonathan Boulais;Matthias Trost;Matthias Trost;Christian R Landry;Régis Dieckmann

  • Molecular dissection of the eukaryotic initiation factor 4E (eIF4E) export‐competent RNP

    Ivan Topisirovic;Nadeem Siddiqui;Vincent Leroux Lapointe;Matthias Trost

  • LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages

    Anetta Härtlova;Anetta Härtlova;Susanne Herbst;Susanne Herbst;Julien Peltier;Julien Peltier;Angela Rodgers

  • Inhibition of USP10 induces degradation of oncogenic FLT3

    Ellen L. Weisberg;Nathan J. Schauer;Jing Yang;Ilaria Lamberto

  • Proteomic Identification of Novel Secreted Antibacterial Toxins of the Serratia marcescens Type VI Secretion System

    Maximilian Joseph Fritsch;Katharina Trunk;Juliana Alcoforado Diniz;Manman Guo

  • Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

    Victoria A. McGuire;Tamara Ruiz-Zorrilla Diez;Tamara Ruiz-Zorrilla Diez;Christoph H. Emmerich;Sam Strickson

  • mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

    Valentina Gandin;Laia Masvidal;Marie Cargnello;Laszlo Gyenis

  • Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib.

    Teemu P Miettinen;Julien Peltier;Julien Peltier;Anetta Härtlova;Anetta Härtlova;Marek Gierliński

  • Activation Loop Phosphorylation of ERK3/ERK4 by Group I p21-activated Kinases (PAKs) Defines a Novel PAK-ERK3/4-MAPK-activated Protein Kinase 5 Signaling Pathway

    Paul Déléris;Matthias Trost;Ivan Topisirovic;Pierre-Luc Tanguay

Frequent Co-Authors

Axel Knebel
Axel Knebel University of Dundee
Dario R. Alessi
Dario R. Alessi University of Dundee
Pierre Thibault
Pierre Thibault University of Montreal
Alan R. Prescott
Alan R. Prescott University of Dundee
Bernard Henrissat
Bernard Henrissat Technical University of Denmark
Tracy Palmer
Tracy Palmer Newcastle University
Serge Mostowy
Serge Mostowy London School of Hygiene & Tropical Medicine
Michel Desjardins
Michel Desjardins University of Montreal
Paul Davies
Paul Davies Tufts University
Kay Hofmann
Kay Hofmann University of Cologne

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