World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
99
Citations
35335
World Ranking
8610
National Ranking
4438

Overview

Mark W. Kieran is affiliated with Harvard University in the United States. Their research primarily focuses on pediatric neuro-oncology, molecular biology, and genetics, intersecting clinical and molecular investigations.

Their recent publications cover various aspects of pediatric brain tumors, cancer progression, and immunotherapy. Noteworthy papers include:

  • A phase II study of continuous oral mTOR inhibitor everolimus for recurrent, radiographic-progressive neurofibromatosis type 1-associated pediatric low-grade glioma: a Neurofibromatosis Clinical Trials Consortium study (2020, Neuro-Oncology)
  • Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression (2020, Proceedings of the National Academy of Sciences)
  • ACCELERATE and European Medicines Agency Paediatric Strategy Forum for medicinal product development of checkpoint inhibitors for use in combination therapy in paediatric patients (2020, European Journal of Cancer)
  • Integrated molecular and clinical analysis of low-grade gliomas in children with neurofibromatosis type 1 (NF1) (2021, Acta Neuropathologica)
  • The current landscape of immunotherapy for pediatric brain tumors (2022, Nature Cancer)

Their frequent co-authors include:

  • Susan Chi
  • Pratiti Bandopadhayay
  • Keith L. Ligon
  • Alaa Elhaddad
  • Andrew D.J. Pearson

Mark W. Kieran has contributed extensively to several publication venues, notably:

  • Neuro-Oncology
  • European Journal of Cancer
  • Cancer Research
  • Pediatric Blood & Cancer
  • Journal of Clinical Oncology

Their main fields of study are Medicine and Biochemistry, Genetics and Molecular Biology. Subfields explored include Genetics, Molecular Biology, Neurology, Pediatrics, Perinatology and Child Health, and Oncology.

The scientist's research topics cover:

  • Glioma Diagnosis and Treatment
  • Neuroblastoma Research and Treatments
  • Childhood Cancer Survivors' Quality of Life
  • Neurofibromatosis and Schwannoma Cases
  • Sarcoma Diagnosis and Treatment
  • Chromatin Remodeling and Cancer
  • CAR-T cell therapy research

Best Publications

  • The DNA binding subunit of NF-κB is identical to factor KBF1 and homologous to the rel oncogene product

    Mark Kieran;Volker Blank;Frédérique Logeat;Joël Vandekerckhove

  • Identification of fibroblast heterogeneity in the tumor microenvironment

    Hikaru Sugimoto;Thomas M Mundel;Mark W. Kieran;Raghu Kalluri;Raghu Kalluri

  • Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

    David T W Jones;Barbara Hutter;Natalie Jäger;Andrey Korshunov;Andrey Korshunov

  • Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

    Marcel Kool;David T.W. Jones;Natalie Jäger;Paul A. Northcott

  • Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria

    Hikaru Sugimoto;Yuki Hamano;David Charytan;Dominic Cosgrove

  • A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors

    Joshua B. Rubin;Andrew L. Kung;Robyn S. Klein;Jennifer A. Chan

  • Challenges to curing primary brain tumours

    Kenneth Aldape;Kevin M Brindle;Louis Chesler;Rajesh Chopra

  • In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

    James E. Dahlman;Carmen Barnes;Omar F. Khan;Aude Thiriot

  • Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

    Mariella G. Filbin;Itay Tirosh;Itay Tirosh;Volker Hovestadt;Volker Hovestadt;McKenzie L. Shaw;McKenzie L. Shaw

  • Intraembryonic hematopoietic cell migration during vertebrate development

    H W Detrich;M W Kieran;F Y Chan;L M Barone

  • Myelopoiesis in the zebrafish, Danio rerio

    Carolyn M. Bennett;Carolyn M. Bennett;Carolyn M. Bennett;John P. Kanki;John P. Kanki;John P. Kanki;Jennifer Rhodes;Jennifer Rhodes;Jennifer Rhodes;Ting X. Liu;Ting X. Liu;Ting X. Liu

  • The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis.

    M. A. Thompson;D. G. Ransom;S. J. Pratt;H. Maclennan

  • Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma

    Adam M. Fontebasso;Simon Papillon-Cavanagh;Jeremy Schwartzentruber;Hamid Nikbakht

  • Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

    Priscilla K Brastianos;Amaro Taylor-Weiner;Peter E Manley;Robert T Jones

  • Platelets actively sequester angiogenesis regulators

    Giannoula Lakka Klement;Giannoula Lakka Klement;Tai-Tung Yip;Flavia Cassiola;Lena Kikuchi

  • Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor

    Susan N. Chi;Mary Ann Zimmerman;Xiaopan Yao;Kenneth J. Cohen

  • Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples

    Laura E. MacConaill;Catarina D. Campbell;Sarah M. Kehoe;Adam J. Bass

  • Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

    Lindsey M. Hoffman;Sophie E.M.Veldhuijzen Van Zanten;Niclas Colditz;Joshua Baugh

  • Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome

    Leslie B. Gordon;Monica E. Kleinman;David T. Miller;Donna S. Neuberg

  • PPARα agonist fenofibrate suppresses tumor growth through direct and indirect angiogenesis inhibition

    Dipak Panigrahy;Arja Kaipainen;Sui Huang;Catherine E. Butterfield

Frequent Co-Authors

Keith L. Ligon
Keith L. Ligon Harvard University
Rameen Beroukhim
Rameen Beroukhim Harvard University
Roger J. Packer
Roger J. Packer Children’s National Health System
Eric Bouffet
Eric Bouffet University of Toronto
Scott L. Pomeroy
Scott L. Pomeroy Boston Children's Hospital
Sandro Santagata
Sandro Santagata Brigham and Women's Hospital
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Charles D. Stiles
Charles D. Stiles Harvard University
Cynthia Hawkins
Cynthia Hawkins University of Toronto
Nada Jabado
Nada Jabado McGill University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring medicine in the USA can open doors to diverse and rewarding career pathways. Many students now consider online degrees for increased flexibility and specialized learning. For those interested in promoting wellness, an online bachelor's degree in nutrition prepares graduates for roles in dietetics, public health, and food science.

Healthcare administration is another in-demand field. Enrolling in cahme-accredited online MHA programs ensures a curriculum that meets rigorous industry standards, ideal for those pursuing healthcare leadership.

Nursing professionals seeking advancement can explore rn to bsn no clinical hours programs, offering a convenient path for working RNs to gain their bachelor's degree without additional clinical requirements.

For those aspiring to the highest level of nursing, accelerated msn to dnp programs allow experienced nurses to earn a Doctor of Nursing Practice in a condensed timeframe.

These online degrees can help shape fulfilling careers across the healthcare landscape, whether in patient care, administration, or public health.

Best Scientists Citing Mark W. Kieran

Trending Scientists