What is he best known for?
The fields of study he is best known for:
Charles D. Stiles mostly deals with Growth factor, Platelet-derived growth factor, Platelet-derived growth factor receptor, Molecular biology and Cell biology.
His Growth factor study incorporates themes from Cell culture, Neural tube, Coactivator, Transcription and DNA synthesis.
The study incorporates disciplines such as FGF1 and Autocrine signalling in addition to Platelet-derived growth factor.
His research integrates issues of Cell growth, Structural gene, Tyrosine phosphorylation, cDNA library and Regulation of gene expression in his study of Platelet-derived growth factor receptor.
His Molecular biology study combines topics from a wide range of disciplines, such as Gene product, Gene expression, FGF10, Floor plate and Ectopic expression.
His Cell biology study integrates concerns from other disciplines, such as Cell cycle, Forebrain, Cerebrum and 3T3 cells.
His most cited work include:
- Cell-Specific Regulation of the c-myc Gene by Lymphocyte Mitogens and Platelet-Derived Growth Factor (1762 citations)
- Common Developmental Requirement for Olig Function Indicates a Motor Neuron/Oligodendrocyte Connection (835 citations)
- Dual control of cell growth by somatomedins and platelet-derived growth factor (795 citations)
What are the main themes of his work throughout his whole career to date?
His primary scientific interests are in Cell biology, Platelet-derived growth factor receptor, Molecular biology, Growth factor and Platelet-derived growth factor.
Charles D. Stiles interconnects Genetics, Transcription factor, OLIG2, Cell cycle and Tissue culture in the investigation of issues within Cell biology.
His Platelet-derived growth factor receptor research includes themes of Cycloheximide, Messenger RNA, Transcription and Signal transduction.
The various areas that Charles D. Stiles examines in his Molecular biology study include Gene expression, Biochemistry, Complementary DNA, Gene and Regulation of gene expression.
His work in Growth factor tackles topics such as Cell culture which are related to areas like Cancer research, In vitro and Cell.
His work deals with themes such as Epidermal growth factor, Autocrine signalling and Endocrinology, which intersect with Platelet-derived growth factor.
He most often published in these fields:
- Cell biology (31.20%)
- Platelet-derived growth factor receptor (23.50%)
- Molecular biology (23.08%)
What were the highlights of his more recent work (between 2010-2021)?
- Glioma (10.26%)
- Cancer research (17.09%)
- Cancer (6.84%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Glioma, Cancer research, Cancer, OLIG2 and Transcription factor.
His study in Cancer research is interdisciplinary in nature, drawing from both MYB, Cell, Progenitor and Kinase.
His Cancer research is multidisciplinary, incorporating elements of Progenitor cell, Gene and Vulnerability.
His Progenitor cell study is related to the wider topic of Cell biology.
His research investigates the connection with OLIG2 and areas like Phosphorylation which intersect with concerns in Molecular biology, Small hairpin RNA, Histone and Neural stem cell.
His study in the fields of Oligodendrocyte Transcription Factor 2 under the domain of Transcription factor overlaps with other disciplines such as Strategic research.
Between 2010 and 2021, his most popular works were:
- Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1 (142 citations)
- MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. (134 citations)
- The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma. (114 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Glioma, Cancer research, Transcription factor, OLIG2 and Gene.
His Glioma research includes themes of Gene duplication, Targeted therapy, Clinical trial and Oncology.
He has included themes like Genotyping, KRAS, MYB and Kinase in his Cancer research study.
His Transcription factor study combines topics in areas such as DNA damage, Central nervous system, Mdm2, HEK 293 cells and Cell biology.
His biological study spans a wide range of topics, including Oligodendrocyte Transcription Factor 2, Basic Helix-Loop-Helix Transcription Factors, Divergence, Cell cycle and Neural stem cell.
His research on Gene concerns the broader Genetics.
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