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Charles D. Stiles

Charles D. Stiles

D-Index & Metrics

Biology and Biochemistry

D-Index
90
Citations
34509
World Ranking
2411
National Ranking
1279

Overview

Charles D. Stiles is affiliated with Harvard University in the United States. Their research spans several main fields including Biochemistry, Genetics and Molecular Biology, with additional work in Medicine. Within these fields, their subfields of study cover Molecular Biology, Genetics, Cancer Research, Infectious Diseases, and Pathology and Forensic Medicine.

Their scientific contributions have appeared in multiple publication venues, notably in Neuro-Oncology with four papers, Cancer Discovery, Neuro-Oncology Advances, and the International Journal of Radiation Oncology*Biology*Physics.

Frequent coauthors collaborating with Charles D. Stiles include Michael S. Regan, Nathalie Y.R. Agar, Daphne A. Haas-Kogan, Sylwia A. Stopka, and Mariella G. Filbin. These collaborations have resulted in several publications in overlapping areas of study.

Their recent research papers include the following works:

  • BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma (2022, Cancer Discovery)
  • DDRE-32. Therapeutic Targeting of a Novel Metabolic Addiction in Diffuse Midline Glioma (2021, Neuro-Oncology Advances)
  • HGG-38. De Novo Pyrimidine Synthesis Inhibition Induces Replication Catastrophe Mediated Cell Death in Diffuse Midline Glioma (2021, Neuro-Oncology)
  • DIPG-19. BAF Complex Perturbation as a Novel Therapeutic Opportunity in H3K27M Pediatric Glioma (2023, Neuro-Oncology)
  • Automated Radiation Response Assessment with Deep Learning and Radiomics in Pediatric Diffuse Midline Glioma (2025, International Journal of Radiation Oncology*Biology*Physics)

Their main topics of work largely revolve around Chromatin Remodeling and Cancer, Glioma Diagnosis and Treatment, and Biochemical and Molecular Research. Other significant thematic areas include RNA modifications and cancer, Protein Degradation and Inhibitors, Cancer, Hypoxia, and Metabolism, as well as HIV/AIDS drug development and treatment.

Best Publications

  • Cell-Specific Regulation of the c-myc Gene by Lymphocyte Mitogens and Platelet-Derived Growth Factor

    Kathleen Kelly;Brent H. Cochran;Charles D. Stiles;Philip Leder

  • Dual control of cell growth by somatomedins and platelet-derived growth factor

    C D Stiles;G T Capone;C D Scher;H N Antoniades

  • Common Developmental Requirement for Olig Function Indicates a Motor Neuron/Oligodendrocyte Connection

    Q.Richard Lu;Tao Sun;Zhimin Zhu;Nan Ma

  • Molecular cloning of gene sequences regulated by platelet-derived growth factor

    Brent H. Cochran;Angela C. Reffel;Charles D. Stiles

  • Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system.

    Q. Richard Lu;Dong In Yuk;John A. Alberta;Zhimin Zhu

  • Induction of DNA synthesis in BALB/c 3T3 cells by serum components: Reevaluation of the commitment process

    W. J. Pledger;C. D. Stiles;H. N. Antoniades;C. D. Scher

  • Purification of human platelet-derived growth factor.

    Harry N. Antoniades;Charles D. Scher;Charles D. Stiles

  • Basic Helix-Loop-Helix Factors in Cortical Development

    Sarah E Ross;Michael E Greenberg;Charles D Stiles

  • Functional role for c-myc in mitogenic response to platelet-derived growth factor.

    H. A. Armelin;M. C. S. Armelin;K. Kelly;T. Stewart

  • An ordered sequence of events is required before BALB/c-3T3 cells become committed to DNA synthesis

    W. J. Pledger;C. D. Stiles;H. N. Antoniades;C. D. Scher

  • Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties

    Barrett J. Rollins;Elizabeth D. Morrison;Charles D. Stiles

  • Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.

    Keith L. Ligon;Emmanuelle Huillard;Emmanuelle Huillard;Shwetal Mehta;Santosh Kesari

  • Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor

    Brent H. Cochran;John Zullo;Inder M. Verma;Charles D. Stiles

  • A HIF1α Regulatory Loop Links Hypoxia and Mitochondrial Signals in Pheochromocytomas

    Patricia L. M. Dahia;Ken N Ross;Matthew E Wright;Cesar Y. Hayashida

  • bHLH Transcription Factor Olig1 Is Required to Repair Demyelinated Lesions in the CNS

    Heather A. Arnett;Stephen P. J. Fancy;John A. Alberta;Chao Zhao

  • Phase I/II Study of Imatinib Mesylate for Recurrent Malignant Gliomas: North American Brain Tumor Consortium Study 99-08

    Patrick Y. Wen;W. K Alfred Yung;Kathleen R. Lamborn;Patricia L. Dahia

  • Platelet-derived growth factor and the regulation of the mammalian fibroblast cell cycle

    Charles D. Scher;Robert C. Shepard;Harry N. Antoniades;Charles D. Stiles

  • Platelet alpha granules contain a growth factor for fibroblasts.

    David R. Kaplan;Francis C. Chao;Charles D. Stiles;Harry N. Antoniades

  • Molecular mechanisms controlling cortical gliogenesis.

    Claire M Sauvageot;Charles D Stiles

  • Review Basic Helix-Loop-Helix Factors in Cortical Development

    Sarah E. Ross;Michael E. Greenberg;Charles D. Stiles

Frequent Co-Authors

Keith L. Ligon
Keith L. Ligon Harvard University
David H. Rowitch
David H. Rowitch University of Cambridge
Rameen Beroukhim
Rameen Beroukhim Harvard University
Mark W. Kieran
Mark W. Kieran Harvard University
Barrett J. Rollins
Barrett J. Rollins Brigham and Women's Hospital
Rosalind A. Segal
Rosalind A. Segal Harvard University
Santosh Kesari
Santosh Kesari University of California, San Diego
Milton H. Saier
Milton H. Saier University of California, San Diego
Sandro Santagata
Sandro Santagata Brigham and Women's Hospital
Patrick Y. Wen
Patrick Y. Wen Harvard University

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