2021 - King Faisal Prize
Robin J.M. Franklin mostly deals with Remyelination, Neuroscience, Oligodendrocyte, Multiple sclerosis and Myelin. His Remyelination study combines topics in areas such as Oligodendrocyte differentiation, Cell biology, Immunology and CNS demyelination. He has included themes like White matter, Cellular differentiation, Regeneration and Pathology in his Neuroscience study.
His biological study spans a wide range of topics, including Progenitor cell, Demyelinating disease, Neuroglia and Lesion. His Multiple sclerosis research incorporates themes from Regenerative process, Genetic analysis, Gene and Disease. The various areas that he examines in his Myelin study include Wnt signaling pathway, Neuregulin, Signal transduction and Neuregulin 1.
His primary areas of study are Remyelination, Neuroscience, Oligodendrocyte, Myelin and Multiple sclerosis. His Remyelination study combines topics from a wide range of disciplines, such as Regeneration, Cell biology, Immunology and Transplantation. His research investigates the link between Neuroscience and topics such as Stem cell that cross with problems in Adult stem cell.
Robin J.M. Franklin works mostly in the field of Oligodendrocyte, limiting it down to topics relating to Progenitor cell and, in certain cases, Cell, as a part of the same area of interest. The study incorporates disciplines such as White matter and Microglia in addition to Myelin. His study in Multiple sclerosis is interdisciplinary in nature, drawing from both Precursor cell and Oligodendrocyte progenitor.
His scientific interests lie mostly in Remyelination, Neuroscience, Myelin, Cell biology and Multiple sclerosis. His Remyelination study is concerned with Central nervous system in general. Robin J.M. Franklin has researched Neuroscience in several fields, including Stem cell, Neural stem cell, Disease and Cell type.
His work in Myelin tackles topics such as White matter which are related to areas like Neurodegeneration. His study looks at the relationship between Cell biology and fields such as Lesion, as well as how they intersect with chemical problems. The concepts of his Multiple sclerosis study are interwoven with issues in Regenerative process, Oligodendrocyte progenitor and Microglia.
Remyelination, Neuroscience, Myelin, Cell biology and Oligodendrocyte are his primary areas of study. His Remyelination research is multidisciplinary, relying on both Cellular differentiation, Progenitor cell, Stem cell and Multiple sclerosis, Immunology. His study in Neuroscience focuses on Central nervous system and Oligodendrocyte differentiation.
Robin J.M. Franklin interconnects White matter, Innate immune system and Embryonic stem cell in the investigation of issues within Myelin. His work on Cell delivery as part of general Cell biology research is frequently linked to Water exchange, bridging the gap between disciplines. His Oligodendrocyte study integrates concerns from other disciplines, such as Lineage, Neuroglia, Phenotype, Mechanotransduction and Axon.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Remyelination in the CNS: from biology to therapy
Robin J. M. Franklin;Charles ffrench-Constant.
Nature Reviews Neuroscience (2008)
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
Veronique E. Miron;Amanda Boyd;Jing Wei Zhao;Tracy J. Yuen;Tracy J. Yuen.
Nature Neuroscience (2013)
Why does remyelination fail in multiple sclerosis
Robin J. M. Franklin.
Nature Reviews Neuroscience (2002)
Debris clearance by microglia: an essential link between degeneration and regeneration
H P H Neumann;M. R. Kotter;R J M Franklin.
Brain (2008)
Rejuvenation of regeneration in the aging central nervous system
Julia M. Ruckh;Jing-Wei Zhao;Jennifer L. Shadrach;Peter van Wijngaarden.
Cell Stem Cell (2012)
Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation.
Mark R. Kotter;Wen-Wu Li;Chao Zhao;Robin J. M. Franklin.
The Journal of Neuroscience (2006)
Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS
Stephen P.J. Fancy;Sergio E. Baranzini;Chao Zhao;Dong-In Yuk.
Genes & Development (2009)
CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.
Malgorzata Zawadzka;Malgorzata Zawadzka;Leanne E. Rivers;Stephen P.J. Fancy;Stephen P.J. Fancy;Chao Zhao.
Cell Stem Cell (2010)
The Age-Related Decrease in CNS Remyelination Efficiency Is Attributable to an Impairment of Both Oligodendrocyte Progenitor Recruitment and Differentiation
Fraser J. Sim;Chao Zhao;Jacques Penderis;Jacques Penderis;Robin J. M. Franklin.
The Journal of Neuroscience (2002)
Repair of demyelinated lesions by transplantation of purified O-2A progenitor cells
A. K. Groves;S. C. Barnett;R. J. M. Franklin;A. J. Crang.
Nature (1993)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:
University of Cambridge
University of Edinburgh
University of Cambridge
University of Edinburgh
Max Planck Society
École Polytechnique Fédérale de Lausanne
University College London
University of Cambridge
University of Cambridge
Paracelsus Medical University
Syracuse University
Universiti Teknologi Petronas
Université Gustave Eiffel
Yıldız Technical University
Nanjing University of Finance and Economics
Kyoto Prefectural University of Medicine
Institute Curie
Cardiff University
Duke University
Berkeley Geochronology Center
Örebro University
University of North Texas
Medical College of Wisconsin
University of Arizona
University of Eastern Finland
University of Tokyo