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Neuroscience

D-Index
34
Citations
8773
World Ranking
9259
National Ranking
3908

Overview

Stephen P.J. Fancy is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, molecular biology, and neuroscience.

The scientist's work spans multiple subfields including molecular biology, neurology, developmental neuroscience, immunology, and oncology. Key areas of study involve neuroinflammation and neurodegeneration mechanisms, neurogenesis and neuroplasticity mechanisms, RNA research and splicing, cytokine signaling pathways and interactions, single-cell and spatial transcriptomics, axon guidance and neuronal signaling, and zebrafish biomedical research applications.

Recent notable publications by Stephen P.J. Fancy include:

  • CNS fibroblasts form a fibrotic scar in response to immune cell infiltration, 2021, Nature Neuroscience
  • CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states, 2022, Nature Neuroscience
  • Astrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during development, 2022, Neuron
  • Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturation, 2021, Neuron
  • Mechanisms of oligodendrocyte progenitor developmental migration, 2021, Developmental Neurobiology

The venues where this scientist frequently publishes include:

  • Nature Neuroscience
  • Neuron
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Developmental Neurobiology
  • Journal of Neuroinflammation

Stephen P.J. Fancy collaborates regularly with several scholars, including:

  • Wenlong Xia
  • Kimberly K. Hoi
  • Kun Leng
  • Indigo V.L. Rose
  • Brendan Rooney

Best Publications

  • CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination.

    Malgorzata Zawadzka;Malgorzata Zawadzka;Leanne E. Rivers;Stephen P.J. Fancy;Stephen P.J. Fancy;Chao Zhao

  • Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

    Stephen P.J. Fancy;Sergio E. Baranzini;Chao Zhao;Dong-In Yuk

  • Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

    Hui-Hsin Tsai;Huiliang Li;Luis C. Fuentealba;Anna V. Molofsky

  • bHLH Transcription Factor Olig1 Is Required to Repair Demyelinated Lesions in the CNS

    Heather A. Arnett;Stephen P. J. Fancy;John A. Alberta;Chao Zhao

  • Oligodendrocyte precursors migrate along vasculature in the developing nervous system

    Hui-Hsin Tsai;Jianqin Niu;Roeben Munji;Dimitrios Davalos

  • Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis

    Tracy J. Yuen;John C. Silbereis;Amelie Griveau;Sandra M. Chang

  • Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination

    Stephen P J Fancy;Emily P Harrington;Tracy J Yuen;John C Silbereis

  • Increased expression of Nkx2.2 and Olig2 identifies reactive oligodendrocyte progenitor cells responding to demyelination in the adult CNS

    Stephen P.J. Fancy;Chao Zhao;Robin J.M. Franklin

  • Myelin regeneration: a recapitulation of development?

    Stephen P J Fancy;Jonah R Chan;Sergio E Baranzini;Robin J M Franklin

  • Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery

    Feng Mei;Feng Mei;Klaus Lehmann-Horn;Yun-An A Shen;Kelsey A Rankin

  • Olig gene function in CNS development and disease.

    Keith L. Ligon;Stephen P.J. Fancy;Robin J.M. Franklin;David H. Rowitch

  • Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

    S. Y Christin Chong;Sheila S. Rosenberg;Stephen P J Fancy;Chao Zhao

  • Overcoming remyelination failure in multiple sclerosis and other myelin disorders.

    Stephen P.J. Fancy;Mark R. Kotter;Emily P. Harrington;Jeffrey K. Huang

  • Aberrant oligodendroglial-vascular interactions disrupt the blood-brain barrier, triggering CNS inflammation.

    Jianqin Niu;Jianqin Niu;Hui-Hsin Tsai;Kimberly K Hoi;Nanxin Huang

  • Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage

    Mark A. Petersen;Mark A. Petersen;Jae Kyu Ryu;Kae Jiun Chang;Ainhoa Etxeberria

  • CNS fibroblasts form a fibrotic scar in response to immune cell infiltration

    Cayce E. Dorrier;Dvir Aran;Ezekiel A. Haenelt;Ryan N. Sheehy

  • Oligodendrocyte PTEN is required for myelin and axonal integrity, not remyelination.

    Emily P. Harrington;Chao Zhao;Stephen P. J. Fancy;Sovann Kaing

  • CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states

    Unknown

  • Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia.

    Fei Wang;Yu-Jian Yang;Nian Yang;Xian-Jun Chen

  • Parallel states of pathological Wnt signaling in neonatal brain injury and colon cancer

    Stephen P J Fancy;Emily P Harrington;Sergio E Baranzini;John C Silbereis

  • Mechanisms of CNS remyelination--the key to therapeutic advances.

    Chao Zhao;Stephen P.J. Fancy;Mark R. Kotter;Wen-Wu Li

  • Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury.

    Bruce A C Cree;Jianqin Niu;Jianqin Niu;Kimberly K Hoi;Chao Zhao

  • Up‐regulation of oligodendrocyte precursor cell αV integrin and its extracellular ligands during central nervous system remyelination

    Chao Zhao;Stephen P.J. Fancy;Robin J.M. Franklin;Charles ffrench-Constant

Frequent Co-Authors

Chao Zhao
Chao Zhao University of Cambridge
Jonah R. Chan
Jonah R. Chan University of California, San Francisco
Nicoletta Kessaris
Nicoletta Kessaris University College London
Erik M. Ullian
Erik M. Ullian University of California, San Francisco
Brian Popko
Brian Popko Northwestern University
Silvia Marino
Silvia Marino Queen Mary University of London
Roland G. Henry
Roland G. Henry University of California, San Francisco
Patrizia Casaccia
Patrizia Casaccia City University of New York
Martina Absinta
Martina Absinta San Raffaele Hospital
Cedric S. Raine
Cedric S. Raine Albert Einstein College of Medicine

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Related Online Degrees & Career Pathways

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