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Neuroscience

D-Index
58
Citations
13208
World Ranking
4150
National Ranking
1879

Overview

Jonah R. Chan is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on neuroscience and medicine, with a strong emphasis on neurology and developmental neuroscience as key subfields.

Chan's work covers various specialized topics including:

  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and neurodegeneration mechanisms
  • Multiple sclerosis research studies
  • Neuroscience and neuropharmacology research
  • Axon guidance and neuronal signaling
  • Nerve injury and regeneration
  • MicroRNA in disease regulation

Their recent publications demonstrate a focus on myelin biology and its role in memory, aging, and neurodegenerative disease. Notable papers include:

  • Preservation of a remote fear memory requires new myelin formation (2020), published in Nature Neuroscience
  • Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer's disease (2021), published in Neuron
  • Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory (2020), published in Nature Neuroscience
  • Myelin plasticity: sculpting circuits in learning and memory (2020), published in Nature Reviews Neuroscience
  • Building a (w)rapport between neurons and oligodendroglia: Reciprocal interactions underlying adaptive myelination (2021), published in Neuron

Chan collaborates frequently with several co-authors, including Ari Green, Wendy Xin, Christian Cordano, Sonia Nocera, and Ahmed Abdelhak. These collaborations are reflected in multiple publications across high-impact neuroscience journals.

The primary venues where Jonah R. Chan has published include:

  • Neuron
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Neuroscience
  • Neurology
  • Brain

Overall, Chan's research contributions are situated at the intersection of cellular and molecular neuroscience, with implications for understanding memory, neurodegenerative conditions, and myelin plasticity processes that impact neural circuit function.

Best Publications

  • Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.

    Feng Mei;Stephen P J Fancy;Yun-An A Shen;Jianqin Niu

  • Clemastine fumarate as a remyelinating therapy for multiple sclerosis (ReBUILD): a randomised, controlled, double-blind, crossover trial

    Ari J Green;Jeffrey M Gelfand;Bruce A Cree;Carolyn Bevan

  • Regulatory T cells promote myelin regeneration in the central nervous system.

    Yvonne Dombrowski;Thomas O'Hagan;Marie Dittmer;Rosana Penalva

  • The Neurotrophin Receptor p75NTR as a Positive Modulator of Myelination

    José M. Cosgaya;Jonah R. Chan;Eric M. Shooter

  • Oligodendrocyte precursors migrate along vasculature in the developing nervous system

    Hui-Hsin Tsai;Jianqin Niu;Roeben Munji;Dimitrios Davalos

  • NGF Controls Axonal Receptivity to Myelination by Schwann Cells or Oligodendrocytes

    Jonah R Chan;Trent A Watkins;José M Cosgaya;ChunZhao Zhang

  • A culture system to study oligodendrocyte myelination processes using engineered nanofibers

    Seonok Lee;Michelle K. Leach;Stephanie A. Redmond;S. Y Christin Chong

  • Olig2 Targets Chromatin Remodelers to Enhancers to Initiate Oligodendrocyte Differentiation

    Yang Yu;Yang Yu;Ying Chen;Bongwoo Kim;Bongwoo Kim;Haibo Wang

  • Astrocyte-encoded positional cues maintain sensorimotor circuit integrity

    Anna V. Molofsky;Kevin W. Kelley;Hui-Hsin Tsai;Stephanie A. Redmond

  • Neurotrophins are key mediators of the myelination program in the peripheral nervous system.

    Jonah R. Chan;José Miguel Cosgaya;Yong Jian Wu;Eric M. Shooter

  • Myelin regeneration: a recapitulation of development?

    Stephen P J Fancy;Jonah R Chan;Sergio E Baranzini;Robin J M Franklin

  • Preservation of a remote fear memory requires new myelin formation.

    Simon Pan;Sonia R. Mayoral;Hye Sun Choi;Jonah R. Chan

  • Accelerated remyelination during inflammatory demyelination prevents axonal loss and improves functional recovery

    Feng Mei;Feng Mei;Klaus Lehmann-Horn;Yun-An A Shen;Kelsey A Rankin

  • Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer's disease.

    Jing-Fei Chen;Kun Liu;Bo Hu;Rong-Rong Li

  • The geometric and spatial constraints of the microenvironment induce oligodendrocyte differentiation.

    Sheila S. Rosenberg;Eve E. Kelland;Eleonora Tokar;Asia R. De La Torre

  • Myelin degeneration and diminished myelin renewal contribute to age-related deficits in memory.

    Fei Wang;Shu-Yu Ren;Jing-Fei Chen;Kun Liu

  • Myelin plasticity: sculpting circuits in learning and memory.

    Wendy Xin;Jonah R. Chan

  • Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

    S. Y Christin Chong;Sheila S. Rosenberg;Stephen P J Fancy;Chao Zhao

  • Glucocorticoids and progestins signal the initiation and enhance the rate of myelin formation.

    Jonah R. Chan;Lornie J. Phillips;Michael Glaser

  • Multiple sclerosis: Prospects and promise.

    Stephen L. Hauser;Jonah R. Chan;Jorge R. Oksenberg

  • Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases

    Junji Yamauchi;Jonah R. Chan;Eric M. Shooter

  • NGF Regulates the Expression of Axonal LINGO-1 to Inhibit Oligodendrocyte Differentiation and Myelination

    Xinhua Lee;Zhongshu Yang;Zhaohui Shao;Sheila S. Rosenberg

  • Schwann cells and astrocytes induce synapse formation by spinal motor neurons in culture.

    E.M Ullian;B.T Harris;A Wu;J.R Chan

Frequent Co-Authors

Stephen P.J. Fancy
Stephen P.J. Fancy University of California, San Francisco
Erik M. Ullian
Erik M. Ullian University of California, San Francisco
Chao Zhao
Chao Zhao University of Cambridge
Roland G. Henry
Roland G. Henry University of California, San Francisco
Brian Popko
Brian Popko Northwestern University
David A. Lyons
David A. Lyons University of Edinburgh
Ben A. Barres
Ben A. Barres Stanford University
Bruce D. Carter
Bruce D. Carter Vanderbilt University
Christiane Zweier
Christiane Zweier University of Erlangen-Nuremberg
Jorge R. Oksenberg
Jorge R. Oksenberg University of California, San Francisco

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