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Wiebke Möbius

Wiebke Möbius

D-Index & Metrics

Biology and Biochemistry

D-Index
75
Citations
21321
World Ranking
5290
National Ranking
383

Overview

Wiebke Möbius is affiliated with the Max Planck Society in Germany. Their research spans multiple disciplines including Neuroscience, Biochemistry, Genetics and Molecular Biology, and Medicine. The scientist's work incorporates subfields such as Molecular Biology, Neurology, Developmental Neuroscience, Cellular and Molecular Neuroscience, and Physiology.

The scientist's recent publications include significant contributions to the understanding of neurodegenerative diseases and cellular processes. Recent papers are:

  • Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease, 2023, Nature
  • Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis, 2020, Nature Neuroscience
  • MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation, 2020, The EMBO Journal
  • Oligodendrocytes support axonal transport and maintenance via exosome secretion, 2020, PLoS Biology
  • Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS, 2024, Nature Medicine

The scientist collaborates frequently with peers including Torben Ruhwedel, Klaus-Armin Nave, Hauke Werner, Anna M. Steyer, and Ting Sun.

Publication venues where Möbius' work appears often include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • EMPIAR dataset
  • Nature Neuroscience
  • Nature Communications
  • Glia

Core research topics addressed by Wiebke Möbius encompass:

  • Neurogenesis and neuroplasticity mechanisms
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Hereditary Neurological Disorders
  • S100 Proteins and Annexins
  • RNA Research and Splicing
  • Nuclear Structure and Function
  • Advanced Neuroimaging Techniques and Applications

Best Publications

  • Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

    Ursula Fünfschilling;Lotti Marianna Supplie;Don Mahad;Don Mahad;Susann Boretius

  • Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.

    Richard Wubbolts;Rachel S. Leckie;Peter T.M. Veenhuizen;Guenter Schwarzmann

  • Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

    Carsten Frühbeis;Dominik Fröhlich;Wen Ping Kuo;Jesa Amphornrat

  • High cholesterol level is essential for myelin membrane growth.

    Gesine Saher;Britta Brügger;Corinna Lappe-Siefke;Wiebke Möbius

  • Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A–C

    Chieh Hsu;Yuichi Morohashi;Shin-ichiro Yoshimura;Natalia Manrique-Hoyos

  • Oligodendroglial NMDA receptors regulate glucose import and axonal energy metabolism.

    Aiman S. Saab;Iva D. Tzvetavona;Andrea Trevisiol;Selva Baltan

  • Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?

    Eva-Maria Krämer-Albers;Niko Bretz;Stefan Tenzer;Christine Winterstein

  • Recycling Compartments and the Internal Vesicles of Multivesicular Bodies Harbor Most of the Cholesterol Found in the Endocytic Pathway

    W. Möbius;E. Van Donselaar;Y. Ohno-Iwashita;Y. Shimada

  • Myelin Membrane Wrapping of CNS Axons by PI(3,4,5)P3-Dependent Polarized Growth at the Inner Tongue

    Nicolas Snaidero;Wiebke Möbius;Tim Czopka;Liesbeth H.P. Hekking

  • Arabidopsis sterol endocytosis involves actin-mediated trafficking via ARA6-positive early endosomes.

    Markus Grebe;Jian Xu;Wiebke Möbius;Takashi Ueda

  • Defective cholesterol clearance limits remyelination in the aged central nervous system

    Ludovico Cantuti-Castelvetri;Dirk Fitzner;Dirk Fitzner;Mar Bosch-Queralt;Marie-Theres Weil;Marie-Theres Weil

  • Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.

    Sandra Goebbels;Jan H Oltrogge;Robert Kemper;Ingo Heilmann

  • Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O.

    Wiebke Möbius;Yoshiko Ohno-Iwashita;Elly G. van Donselaar;Viola M.J. Oorschot

  • Exosome Secretion Ameliorates Lysosomal Storage of Cholesterol in Niemann-Pick Type C Disease

    Katrin Strauss;Cornelia Goebel;Heiko Runz;Wiebke Möbius

  • Proteolipid protein is required for transport of sirtuin 2 into CNS myelin

    Hauke B. Werner;Katja Kuhlmann;Siming Shen;Marina Uecker

  • Transplantation reveals regional differences in oligodendrocyte differentiation in the adult brain

    Francesca Viganò;Wiebke Möbius;Magdalena Götz;Leda Dimou

  • Drosophila Auditory Organ Genes and Genetic Hearing Defects

    Pingkalai R. Senthilan;David Piepenbrock;Guvanch Ovezmyradov;Björn Nadrowski

  • Cryo FIB-SEM: volume imaging of cellular ultrastructure in native frozen specimens.

    Andreas Schertel;Nicolas Snaidero;Hong-Mei Han;Torben Ruhwedel

  • Platelets, endothelial cells and leukocytes contribute to the exercise-triggered release of extracellular vesicles into the circulation

    Alexandra Brahmer;Elmo Neuberger;Leona Esch-Heisser;Nils Haller

  • The Axon-Myelin Unit in Development and Degenerative Disease.

    Ruth M. Stassart;Wiebke Möbius;Klaus-Armin Nave;Julia M. Edgar;Julia M. Edgar

Frequent Co-Authors

Klaus-Armin Nave
Klaus-Armin Nave Max Planck Society
Mikael Simons
Mikael Simons German Center for Neurodegenerative Diseases
Sandra Goebbels
Sandra Goebbels Max Planck Society
Stefan Tenzer
Stefan Tenzer Johannes Gutenberg University of Mainz
Olaf Jahn
Olaf Jahn Max Planck Society
Johannes Hirrlinger
Johannes Hirrlinger Leipzig University
Hans J. Geuze
Hans J. Geuze Utrecht University
Frank Kirchhoff
Frank Kirchhoff University of Ulm
Jacqueline Trotter
Jacqueline Trotter Johannes Gutenberg University of Mainz
Matthias Klugmann
Matthias Klugmann University of New South Wales

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