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Biology and Biochemistry

D-Index
52
Citations
10436
World Ranking
16632
National Ranking
1160

Overview

Jacqueline Trotter is affiliated with Johannes Gutenberg University of Mainz in Germany. Their research focuses primarily on neuroscience and the biochemistry, genetics, and molecular biology aspects underlying neural mechanisms.

Their work spans several specialized subfields including molecular biology, behavioral neuroscience, developmental neuroscience, biological psychiatry, and cancer research.

Key topics addressed in their research include stress responses and cortisol regulation, the role of tryptophan in brain disorders, microRNA in disease regulation, anesthesia and neurotoxicity, birth and developmental health, adipose tissue and metabolism, and neuroinflammation with mechanisms of neurodegeneration.

Trotter has coauthored multiple publications with several frequent collaborators. These coauthors include Giulia Treccani, Hatice Yiğit, Thomas Lingner, Malin Wennström, and David P. Herzog.

Their recent scientific papers, which collectively contribute to understanding the effects of early life stress and adversity on the nervous system, include:

  • Early life adversity targets the transcriptional signature of hippocampal NG2+ glia and affects voltage gated sodium (Nav) channels properties, 2021, Neurobiology of Stress
  • Early life stress induces long lasting changes in the oligodendrocyte precursor cell transcriptome and alterations in Nav-channel density, 2020, Gates Open Res
  • Early life stress programming of NG2+ glia transcriptome alters functional properties of voltage gated sodium (Nav) channels and cognitive performance, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Early Life Stress Programming of NG2+ Glia Transcriptome Alters Functional Properties of Voltage Gated Sodium (Nav) Channels and Cognitive Performance, 2021, Biological Psychiatry
  • P.0188 Early life stress targets the transcriptional signature and functional properties of voltage gated-sodium (nav) channels in hippocampal NG2+ GLIA, 2021, European Neuropsychopharmacology

Significant publication venues for Trotter's work include Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, bioRxiv (Cold Spring Harbor Laboratory), Neurobiology of Stress, Gates Open Res, and Biological Psychiatry.

Best Publications

  • Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte–Neuron Communication

    Carsten Frühbeis;Dominik Fröhlich;Wen Ping Kuo;Jesa Amphornrat

  • T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination

    Scott Zamvil;Patricia Nelson;Jacqueline Trotter;Dennis Mitchell

  • Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?

    Eva-Maria Krämer-Albers;Niko Bretz;Stefan Tenzer;Christine Winterstein

  • Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation.

    Dominik Fröhlich;Wen Ping Kuo;Carsten Frühbeis;Jyh-Jang Sun

  • Assembly of myelin by association of proteolipid protein with cholesterol- and galactosylceramide-rich membrane domains.

    Mikael Simons;Eva-Maria Krämer;Christoph Thiele;Wilhelm Stoffel

  • NG2 cells: Properties, progeny and origin.

    Jacqueline Trotter;Khalad Karram;Akiko Nishiyama

  • Process Outgrowth of Oligodendrocytes Is Promoted by Interaction of Fyn Kinase with the Cytoskeletal Protein Tau

    Corinna Klein;Eva-Maria Krämer;Anne-Marie Cardine;Burkhardt Schraven

  • Characterization of glial trkB receptors: differential response to injury in the central and peripheral nervous systems.

    Jonas Frisen;Valerie M. K. Verge;Kaj Fried;Marten Risling

  • Lines of Murine Oligodendroglial Precursor Cells Immortalized by an Activated neu Tyrosine Kinase Show Distinct Degrees of Interaction with Axons In Vitro and In Vivo

    M. Jung;E. Krämer;M. Grzenkowski;K. Tang

  • Wrapping it up: the cell biology of myelination

    Mikael Simons;Jacqueline Trotter

  • Channel expression correlates with differentiation stage during the development of oligodendrocytes from their precursor cells in culture.

    H. Sontheimer;J. Trotter;M. Schachner;H. Kettenmann

  • Compartmentation of Fyn Kinase with Glycosylphosphatidylinositol-anchored Molecules in Oligodendrocytes Facilitates Kinase Activation during Myelination

    Eva-Maria Krämer;Corinna Klein;Thomas Koch;Monica Boytinck

  • Differentiation-regulated loss of the polysialylated embryonic form and expression of the different polypeptides of the neural cell adhesion molecule by cultured oligodendrocytes and myelin.

    J. Trotter;D. Bitter-Suermann;M. Schachner

  • Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granules.

    Robin White;Constantin Gonsior;Eva-Maria Krämer-Albers;Nadine Stöhr

  • Oligodendrocyte Precursor Cells Modulate the Neuronal Network by Activity-Dependent Ectodomain Cleavage of Glial NG2

    Dominik Sakry;Angela Neitz;Jeet Singh;Renato Frischknecht

  • Overexpression of the myelin proteolipid protein leads to accumulation of cholesterol and proteolipid protein in endosomes/lysosomes: implications for Pelizaeus-Merzbacher disease

    Mikael Simons;Eva-Maria Krämer;Eva-Maria Krämer;Paolo Macchi;Silvia Rathke-Hartlieb

  • Novel NG2‐CreERT2 knock‐in mice demonstrate heterogeneous differentiation potential of NG2 glia during development

    Wenhui Huang;Na Zhao;Xianshu Bai;Khalad Karram

  • AN2/NG2 protein‐expressing glial progenitor cells in the murine CNS: Isolation, differentiation, and association with radial glia

    Marianne Diers-Fenger;Frank Kirchhoff;Helmut Kettenmann;Joel M. Levine

  • Cells positive for the O4 surface antigen isolated by cell sorting are able to differentiate into astrocytes or oligodendrocytes

    Jacqueline Trotter;Melitta Schachner

  • Oligodendrocytes Direct Glycosyl Phosphatidylinositol-anchored Proteins to the Myelin Sheath in Glycosphingolipid-rich Complexes

    Eva-Maria Krämer;Thomas Koch;Antje Niehaus;Jacqueline Trotter

Frequent Co-Authors

Klaus-Armin Nave
Klaus-Armin Nave Max Planck Society
Helmut Kettenmann
Helmut Kettenmann Shenzhen Institutes of Advanced Technology
Melitta Schachner
Melitta Schachner Rutgers, The State University of New Jersey
Marianne B. Müller
Marianne B. Müller Johannes Gutenberg University of Mainz
Sandra Goebbels
Sandra Goebbels Max Planck Society
Frank Kirchhoff
Frank Kirchhoff University of Ulm
Wiebke Möbius
Wiebke Möbius Max Planck Society
Christian Steinhäuser
Christian Steinhäuser University of Bonn
Gregers Wegener
Gregers Wegener Aarhus University
William F. Blakemore
William F. Blakemore University of Cambridge

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