His main research concerns Cell biology, Biochemistry, Transfection, Gene delivery and Biophysics. His Cell biology research incorporates elements of Endocytic cycle, Endocytosis and Internalization. When carried out as part of a general Biochemistry research project, his work on Membrane is frequently linked to work in Mechanism and Fusion protein, therefore connecting diverse disciplines of study.
His study in the field of Cationic liposome also crosses realms of Cytosol. His study in Gene delivery is interdisciplinary in nature, drawing from both Cell, Pyridinium and Oligonucleotide. He has included themes like Lipid bilayer fusion, Liposome, Vesicle, Membrane fluidity and Lipid bilayer in his Biophysics study.
His scientific interests lie mostly in Cell biology, Biochemistry, Vesicle, Biophysics and Lipid bilayer fusion. His Cell biology research includes themes of Endocytosis, Cell membrane and Cell polarity. His work in Membrane, Liposome, Sphingolipid, Transfection and Gene delivery are all subfields of Biochemistry research.
His work in Vesicle covers topics such as Crystallography which are related to areas like Alkyl. His Biophysics research is multidisciplinary, incorporating perspectives in Membrane fluidity and Peptide. His Lipid bilayer fusion research focuses on Sendai virus and how it relates to Viral membrane.
Dick Hoekstra mostly deals with Cell biology, Biochemistry, Myelin, Remyelination and Oligodendrocyte. Cell biology and Cell are frequently intertwined in his study. Within one scientific family, Dick Hoekstra focuses on topics pertaining to Biophysics under Biochemistry, and may sometimes address concerns connected to In vivo.
His Oligodendrocyte research includes elements of Astrocyte and CNS demyelination. His research in Endosome intersects with topics in Hepatic stellate cell, Sodium–hydrogen antiporter, Transfection, Function and Cell membrane. His Intracellular study combines topics in areas such as Internalization, Endocytosis and Basolateral plasma membrane.
Cell biology, Endosome, Biochemistry, Intracellular and Drug delivery are his primary areas of study. His research integrates issues of Oligodendrocyte differentiation, Transporter, Central nervous system, Endocytosis and Cell polarity in his study of Cell biology. His studies in Endocytosis integrate themes in fields like Transfection, Gene delivery, Filopodia, Actin and Internalization.
The various areas that he examines in his Endosome study include Cell culture and Cell membrane. The study incorporates disciplines such as Biophysics and In vivo in addition to Biochemistry. Dick Hoekstra has researched Biophysics in several fields, including Vesicle, In vitro model and Peptide.
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Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis
Joanna Rejman;Volker Oberle;Inge S Zuhorn;Dick Hoekstra.
Biochemical Journal (2004)
USE OF RESONANCE ENERGY-TRANSFER TO MONITOR MEMBRANE-FUSION
Douglas K. Struck;Dick Hoekstra;Richard E. Pagano.
Biochemistry (1981)
FLUORESCENCE METHOD FOR MEASURING THE KINETICS OF FUSION BETWEEN BIOLOGICAL-MEMBRANES
Dick Hoekstra;T Deboer;Katharina Klappe;Jan Wilschut.
Biochemistry (1984)
Cationic lipids, lipoplexes and intracellular delivery of genes
Luc Wasungu;Dick Hoekstra.
Journal of Controlled Release (2006)
Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis.
Inge S. Zuhorn;Ruby Kalicharan;Dick Hoekstra.
Journal of Biological Chemistry (2002)
Gene delivery by cationic lipid vectors: overcoming cellular barriers.
Inge S. Zuhorn;Jan B. F. N. Engberts;Dick Hoekstra.
European Biophysics Journal (2007)
Role of lipid phase separations and membrane hydration in phospholipid vesicle fusion
Dick Hoekstra.
Biochemistry (1982)
PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: regulation of proliferation and differentiation by multiple intracellular signaling pathways.
Wia Baron;B Metz;R Bansal;Dick Hoekstra.
Molecular and Cellular Neuroscience (2000)
Release of outer membrane fragments from normally growing escherichia coli
Dick Hoekstra;Jw Vanderlaan;Loe de Leij;Bernard Witholt.
Biochimica et Biophysica Acta (1976)
Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection efficiency.
Inge S. Zuhorn;Udo Bakowsky;Evgeny Polushkin;Willy H. Visser.
Molecular Therapy (2005)
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