D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 75 Citations 18,792 217 World Ranking 2285 National Ranking 43

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cell membrane
  • Biochemistry

His main research concerns Cell biology, Biochemistry, Transfection, Gene delivery and Biophysics. His Cell biology research incorporates elements of Endocytic cycle, Endocytosis and Internalization. When carried out as part of a general Biochemistry research project, his work on Membrane is frequently linked to work in Mechanism and Fusion protein, therefore connecting diverse disciplines of study.

His study in the field of Cationic liposome also crosses realms of Cytosol. His study in Gene delivery is interdisciplinary in nature, drawing from both Cell, Pyridinium and Oligonucleotide. He has included themes like Lipid bilayer fusion, Liposome, Vesicle, Membrane fluidity and Lipid bilayer in his Biophysics study.

His most cited work include:

  • Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis (2030 citations)
  • USE OF RESONANCE ENERGY-TRANSFER TO MONITOR MEMBRANE-FUSION (1130 citations)
  • FLUORESCENCE METHOD FOR MEASURING THE KINETICS OF FUSION BETWEEN BIOLOGICAL-MEMBRANES (589 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Cell biology, Biochemistry, Vesicle, Biophysics and Lipid bilayer fusion. His Cell biology research includes themes of Endocytosis, Cell membrane and Cell polarity. His work in Membrane, Liposome, Sphingolipid, Transfection and Gene delivery are all subfields of Biochemistry research.

His work in Vesicle covers topics such as Crystallography which are related to areas like Alkyl. His Biophysics research is multidisciplinary, incorporating perspectives in Membrane fluidity and Peptide. His Lipid bilayer fusion research focuses on Sendai virus and how it relates to Viral membrane.

He most often published in these fields:

  • Cell biology (43.65%)
  • Biochemistry (32.82%)
  • Vesicle (27.55%)

What were the highlights of his more recent work (between 2007-2019)?

  • Cell biology (43.65%)
  • Biochemistry (32.82%)
  • Myelin (9.60%)

In recent papers he was focusing on the following fields of study:

Dick Hoekstra mostly deals with Cell biology, Biochemistry, Myelin, Remyelination and Oligodendrocyte. Cell biology and Cell are frequently intertwined in his study. Within one scientific family, Dick Hoekstra focuses on topics pertaining to Biophysics under Biochemistry, and may sometimes address concerns connected to In vivo.

His Oligodendrocyte research includes elements of Astrocyte and CNS demyelination. His research in Endosome intersects with topics in Hepatic stellate cell, Sodium–hydrogen antiporter, Transfection, Function and Cell membrane. His Intracellular study combines topics in areas such as Internalization, Endocytosis and Basolateral plasma membrane.

Between 2007 and 2019, his most popular works were:

  • Mechanism of Polyplex- and Lipoplex-Mediated Delivery of Nucleic Acids: Real-Time Visualization of Transient Membrane Destabilization without Endosomal Lysis (214 citations)
  • Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood–Brain Barrier Endothelial Cells In Vitro (134 citations)
  • How cationic lipids transfer nucleic acids into cells and across cellular membranes: recent advances. (133 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cell membrane
  • Biochemistry

Cell biology, Endosome, Biochemistry, Intracellular and Drug delivery are his primary areas of study. His research integrates issues of Oligodendrocyte differentiation, Transporter, Central nervous system, Endocytosis and Cell polarity in his study of Cell biology. His studies in Endocytosis integrate themes in fields like Transfection, Gene delivery, Filopodia, Actin and Internalization.

The various areas that he examines in his Endosome study include Cell culture and Cell membrane. The study incorporates disciplines such as Biophysics and In vivo in addition to Biochemistry. Dick Hoekstra has researched Biophysics in several fields, including Vesicle, In vitro model and Peptide.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis

Joanna Rejman;Volker Oberle;Inge S Zuhorn;Dick Hoekstra.
Biochemical Journal (2004)

2803 Citations

USE OF RESONANCE ENERGY-TRANSFER TO MONITOR MEMBRANE-FUSION

Douglas K. Struck;Dick Hoekstra;Richard E. Pagano.
Biochemistry (1981)

1795 Citations

FLUORESCENCE METHOD FOR MEASURING THE KINETICS OF FUSION BETWEEN BIOLOGICAL-MEMBRANES

Dick Hoekstra;T Deboer;Katharina Klappe;Jan Wilschut.
Biochemistry (1984)

916 Citations

Cationic lipids, lipoplexes and intracellular delivery of genes

Luc Wasungu;Dick Hoekstra.
Journal of Controlled Release (2006)

669 Citations

Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis.

Inge S. Zuhorn;Ruby Kalicharan;Dick Hoekstra.
Journal of Biological Chemistry (2002)

387 Citations

Gene delivery by cationic lipid vectors: overcoming cellular barriers.

Inge S. Zuhorn;Jan B. F. N. Engberts;Dick Hoekstra.
European Biophysics Journal (2007)

286 Citations

Role of lipid phase separations and membrane hydration in phospholipid vesicle fusion

Dick Hoekstra.
Biochemistry (1982)

284 Citations

PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: regulation of proliferation and differentiation by multiple intracellular signaling pathways.

Wia Baron;B Metz;R Bansal;Dick Hoekstra.
Molecular and Cellular Neuroscience (2000)

272 Citations

Release of outer membrane fragments from normally growing escherichia coli

Dick Hoekstra;Jw Vanderlaan;Loe de Leij;Bernard Witholt.
Biochimica et Biophysica Acta (1976)

269 Citations

Nonbilayer phase of lipoplex-membrane mixture determines endosomal escape of genetic cargo and transfection efficiency.

Inge S. Zuhorn;Udo Bakowsky;Evgeny Polushkin;Willy H. Visser.
Molecular Therapy (2005)

263 Citations

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