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Neuroscience

D-Index
37
Citations
4551
World Ranking
8855
National Ranking
236

Overview

Wia Baron is affiliated with the University Medical Center Groningen in the Netherlands. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine. Within these, several subfields stand out, including Molecular Biology, Neurology, Developmental Neuroscience, Immunology, and Pathology and Forensic Medicine.

The main topics of their scientific work concentrate on mechanisms of neurogenesis and neuroplasticity, neuroinflammation and neurodegeneration, and studies specifically focused on multiple sclerosis. Other notable topics include protease and inhibitor mechanisms, RNA research and splicing, cell adhesion molecules research, and the role of microRNA in disease regulation.

Among Wia Baron's recent publications are:

  • "Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis" (2022, Brain Behavior and Immunity)
  • "Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination" (2020, Proceedings of the National Academy of Sciences)
  • "Remodeling of the interstitial extracellular matrix in white matter multiple sclerosis lesions: Implications for remyelination (failure)" (2020, Journal of Neuroscience Research)
  • "Matrix metalloproteinases shape the oligodendrocyte (niche) during development and upon demyelination" (2020, Neuroscience Letters)
  • "Macroglial diversity: white and grey areas and relevance to remyelination" (2020, Cellular and Molecular Life Sciences)

The scientist has published in several distinguished venues, with frequent contributions to:

  • Proceedings of the National Academy of Sciences
  • Cellular and Molecular Life Sciences
  • Journal of Neuroinflammation
  • Frontiers in Cellular Neuroscience
  • bioRxiv (Cold Spring Harbor Laboratory)

Wia Baron has collaborated regularly with a group of frequent co-authors including Bart J. L. Eggen, Inge L. Werkman, Rianne P. Gorter, Bieke Broux, and Niels Hellings.

In addition to journal publications, Wia Baron contributed to book literature, specifically with a title published by Frontiers Media in 2023: "Cellular and Molecular Factors that Drive the Behavior of Oligodendrocyte Progenitor Cells in Physiological Conditions and Disease."

Best Publications

  • CNS integrins switch growth factor signalling to promote target-dependent survival.

    Holly Colognato;Wia Baron;Virginia Avellana-Adalid;Jõao B. Relvas

  • PDGF and FGF-2 signaling in oligodendrocyte progenitor cells: regulation of proliferation and differentiation by multiple intracellular signaling pathways

    Wia Baron;B Metz;R Bansal;Dick Hoekstra

  • Fibronectin aggregation in multiple sclerosis lesions impairs remyelination

    Josephine M. J. Stoffels;Jenny C. de Jonge;Mirjana Stancic;Anita Nomden

  • The oligodendrocyte precursor mitogen PDGF stimulates proliferation by activation of αvβ3 integrins

    Wia Baron;Wia Baron;Sanford J. Shattil;Charles ffrench‐Constant

  • Regulation of integrin growth factor interactions in oligodendrocytes by lipid raft microdomains

    Wia Baron;Laurence Decker;Holly Colognato;Charles ffrench-Constant

  • On the biogenesis of myelin membranes: Sorting, trafficking and cell polarity

    Wia Baron;Dick Hoekstra

  • Integrin-growth factor interactions,as regulators of oligodendroglial development and function

    Wia Baron;Holly Colognato;Charles Ffrench-Constant

  • Classically and alternatively activated bone marrow derived macrophages differ in cytoskeletal functions and migration towards specific CNS cell types

    Elly J. F. Vereyken;Priscilla D. A. M. Heijnen;Wia Baron;Elga H. E. de Vries

  • Rafts in oligodendrocytes: Evidence and structure–function relationship

    Ellen Gielen;Wia Baron;Martin Vandeven;Paul Steels

  • Selective modulation of TnF-TnFRs signaling : Insights for multiple sclerosis treatment

    Valentina Pegoretti;Wia Baron;Jon D. Laman;Ulrich L. M. Eisel

  • Expression of dominant-negative and chimeric subunits reveals an essential role for β1 integrin during myelination

    João B. Relvas;Anna Setzu;Wia Baron;Philip C. Buttery

  • Fibronectin in tissue regeneration: timely disassembly of the scaffold is necessary to complete the build

    Josephine M. J. Stoffels;Chao Zhao;Wia Baron

  • Increased expression of distinct galectins in multiple sclerosis lesions.

    M. Stancic;J. van Horssen;V. L. Thijssen;H. J. Gabius

  • Toll-like receptors 2 and 3 agonists differentially affect oligodendrocyte survival, differentiation, and myelin membrane formation.

    Malika Bsibsi;Anita Nomden;Johannes M. van Noort;Wia Baron

  • Fibronectin impedes "myelin" sheet-directed flow in oligodendrocytes : A role for a beta 1 integrin-mediated PKC signaling pathway in vesicular trafficking

    Zuzana Šišková;Wia Baron;Hans de Vries;Dick Hoekstra

  • Alteration of the extracellular matrix interferes with raft association of neurofascin in oligodendrocytes. Potential significance for multiple sclerosis

    Olaf Maier;Tiemen van der Heide;Anne-Marie van Dam;Wia Baron

  • Polarity Development in Oligodendrocytes: Sorting and Trafficking of Myelin Components

    Olaf Maier;Dick Hoekstra;Wia Baron

  • Regulation of oligodendrocyte differentiation: protein kinase C activation prevents differentiation of O2A progenitor cells toward oligodendrocytes

    W Baron;JC de Jonge;de Hans Vries;D Hoekstra

  • Galectin-4, a novel neuronal regulator of myelination.

    Mirjana Stancic;Davor Slijepcevic;Anita Nomden;Michel J. Vos

  • Survival and Functionality of Human Induced Pluripotent Stem Cell-Derived Oligodendrocytes in a Nonhuman Primate Model for Multiple Sclerosis

    Arun Thiruvalluvan;Marcin Czepiel;Yolanda A. Kap;Ietje Mantingh-Otter

  • Lipid rafts: microenvironments for integrin-growth factor interactions in neural development.

    L. Decker;W. Baron;C. ffrench-Constant

  • Fibronectin attenuates process outgrowth in oligodendrocytes by mislocalizing MMP-9 activity

    Zuzana Siskova;V. Wee Yong;Anita Nomden;Miriam van Strien

Frequent Co-Authors

Chao Zhao
Chao Zhao University of Cambridge
Maarten H.P. Kole
Maarten H.P. Kole Utrecht University
Eleonora Aronica
Eleonora Aronica University of Amsterdam
Frank Kirchhoff
Frank Kirchhoff University of Ulm
Bart J. L. Eggen
Bart J. L. Eggen University Medical Center Groningen
Erik Boddeke
Erik Boddeke University Medical Center Groningen
Rashmi Bansal
Rashmi Bansal University of Connecticut
Steven A. Goldman
Steven A. Goldman University of Rochester Medical Center

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Related Online Degrees & Career Pathways

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