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Alessandro Prinetti

Alessandro Prinetti

D-Index & Metrics

Biology and Biochemistry

D-Index
54
Citations
9981
World Ranking
15678
National Ranking
490

Overview

Alessandro Prinetti is affiliated with the University of Milan in Italy and specializes in research intersecting biochemistry, genetics, molecular biology, and medicine. The scientist's work primarily focuses on molecular biology, physiology, immunology, pathology, forensic medicine, and cell biology, reflecting a broad range of biological and medical fields.

The research topics covered by Alessandro Prinetti span sphingolipid metabolism and signaling, lysosomal storage disorders, multiple sclerosis, glycosylation and glycoproteins, lipid membrane structure and behavior, immune cell function and interaction, and mechanisms related to neurogenesis and neuroplasticity.

Frequent publication venues include:

  • Journal of Neurochemistry
  • International Journal of Molecular Sciences
  • The EMBO Journal
  • Cellular Signalling
  • Advances in experimental medicine and biology

Notable recent papers include:

  • The role of Sphingolipids in myelination and myelin stability and their involvement in childhood and adult demyelinating disorders, 2020, Journal of Neurochemistry
  • Homeostatic and pathogenic roles of GM 3 ganglioside molecular species in TLR 4 signaling in obesity, 2020, The EMBO Journal
  • Lipid rafts as platforms for sphingosine 1-phosphate metabolism and signalling, 2021, Cellular Signalling
  • The Role of Sphingolipids in Cancer Immunotherapy, 2021, International Journal of Molecular Sciences
  • Glycosphingolipids, 2021, Advances in experimental medicine and biology

Alessandro Prinetti has collaborated frequently with several co-authors, including Laura Mauri, Simona Prioni, Sara Grassi, Paola Giussani, and Maria Grazia Ciampa. These collaborations involve multiple publications indicating ongoing research partnerships.

The scientist's investigations concentrate on cellular and molecular mechanisms underlying diseases related to sphingolipid metabolism, immune system interactions, and neurological disorders. This includes an emphasis on demyelinating diseases, obesity-associated molecular signaling, and cancer immunotherapy.

Best Publications

  • Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance.

    Kazuya Kabayama;Takashige Sato;Kumiko Saito;Nicoletta Loberto

  • Gangliosides as components of lipid membrane domains

    Sandro Sonnino;Laura Mauri;Vanna Chigorno;Alessandro Prinetti

  • GM3-enriched Microdomain Involved in Cell Adhesion and Signal Transduction through Carbohydrate-Carbohydrate Interaction in Mouse Melanoma B16 Cells

    Kazuhisa Iwabuchi;Soichiro Yamamura;Alessandro Prinetti;Kazuko Handa

  • New insights in glycosphingolipid function: “glycosignaling domain,” a cell surface assembly of glycosphingolipids with signal transducer molecules, involved in cell adhesion coupled with signaling

    Sen-itiroh Hakomori;Kazuko Handa;Kazuhisa Iwabuchi;Soichiro Yamamura

  • Tumor-mediated liver X receptor-[alpha] activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

    Eduardo J. Villablanca;Laura Raccosta;Dan Zhou;Raffaella Fontana

  • Membrane domains and the "lipid raft" concept.

    S Sonnino;A Prinetti

  • The role of sphingolipids in the process of signal transduction

    Laura Riboni;Paola Viani;Rosaria Bassi;Alessandro Prinetti

  • The oxysterol–CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils

    Laura Raccosta;Raffaella Fontana;Daniela Maggioni;Claudia Lanterna

  • Changes in the Lipid Turnover, Composition, and Organization, as Sphingolipid-enriched Membrane Domains, in Rat Cerebellar Granule Cells Developing in Vitro

    Alessandro Prinetti;Vanna Chigorno;Simona Prioni;Nicoletta Loberto

  • Glycosphingolipid-enriched signaling domain in mouse neuroblastoma Neuro2a cells. Mechanism of ganglioside-dependent neuritogenesis.

    Alessandro Prinetti;Kazuhisa Iwabuchi;Sen-itiroh Hakomori

  • Dynamic and structural properties of sphingolipids as driving forces for the formation of membrane domains.

    Sandro Sonnino;Alessandro Prinetti;Laura Mauri;Vanna Chigorno

  • Sphingolipid-enriched Membrane Domains from Rat Cerebellar Granule Cells Differentiated in Culture A COMPOSITIONAL STUDY

    Alessandro Prinetti;Vanna Chigorno;Guido Tettamanti;Sandro Sonnino

  • A Mediator Role of Ceramide in the Regulation of Neuroblastoma Neuro2a Cell Differentiation

    Laura Riboni;Alessandro Prinetti;Rosaria Bassi;Antonella Caminiti

  • The Plasma Membrane-associated Sialidase MmNEU3 Modifies the Ganglioside Pattern of Adjacent Cells Supporting Its Involvement in Cell-to-Cell Interactions

    Nadia Papini;Luigi Anastasia;Cristina Tringali;Gianluigi Croci

  • Glycosphingolipid behaviour in complex membranes.

    Alessandro Prinetti;Nicoletta Loberto;Vanna Chigorno;Sandro Sonnino

  • Plasma membrane production of ceramide from ganglioside GM3 in human fibroblasts

    Rea Valaperta;Vanna Chigorno;Luisa Basso;Alessandro Prinetti

  • GM1 Ganglioside: Past Studies and Future Potential

    Massimo Aureli;Laura Mauri;Maria Grazia Ciampa;Alessandro Prinetti

  • Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders.

    Marco Piccinini;Federica Scandroglio;Simona Prioni;Barbara Buccinnà

  • GM3-enriched microdomain involved in cell adhesion and signal transduction through carbohydrate-carbohydrate interaction in mouse melanoma B16 cells; Separation of'glycosphingolipid signaling domain' from caveolin- containing membrane fraction in mouse melanoma B16 cells and its role in cell adhesion coupled with signaling

    K. Iwabuchi;S. Yamamura;A. Prinetti;K. Handa

  • Abstract LB-346: The Oxysterol-CXCR2 axis plays a key role in the recruitment of tumor promoting neutrophils.

    Vincenzo Russo;Laura Raccosta;Raffaella Fontana;Daniela Maggioni

Frequent Co-Authors

Sandro Sonnino
Sandro Sonnino University of Milan
Laura Mauri
Laura Mauri University of Milan
Guido Tettamanti
Guido Tettamanti University of Milan
Claudio Bordignon
Claudio Bordignon MolMed (Italy)
Edward H. Schuchman
Edward H. Schuchman Icahn School of Medicine at Mount Sinai
Jan-Åke Gustafsson
Jan-Åke Gustafsson University of Houston
Sen-itiroh Hakomori
Sen-itiroh Hakomori Pacific Northwest Diabetes Research Institute
Hideoki Ogawa
Hideoki Ogawa Juntendo University
Catia Traversari
Catia Traversari MolMed (Italy)
Giovanni Tredici
Giovanni Tredici University of Milano-Bicocca

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