D-Index & Metrics Best Publications

Konrad Sandhoff

University of Bonn
Germany

Biology and Biochemistry

Germany

2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name Citations Publications World Ranking National Ranking

Biology and Biochemistry D-index 108 Citations 38,087 439 World Ranking 751 National Ranking 58

Research.com Recognitions

Awards & Achievements

2023 - Research.com Biology and Biochemistry in Germany Leader Award

1999 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Human Genetics and Molecular Medicine

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study Konrad Sandhoff is best known for:

Gene
Enzyme
Sphingolipid

His Primary (astronomy) research focuses on Astronomy and how it connects with Chain (unit). His work on Chain (unit) is being expanded to include thematically relevant topics such as Astronomy. He applies his multidisciplinary studies on Biochemistry and Metabolism in his research. His study brings together the fields of Sphingolipid and Cell biology. Konrad Sandhoff integrates Sphingolipid and Lipid signaling in his studies. His Enzyme study frequently draws connections to adjacent fields such as Substrate specificity. Konrad Sandhoff performs multidisciplinary study in the fields of Gene and Apoptosis via his papers. He performs integrative study on Apoptosis and Ceramide in his works. By researching both Ceramide and Lipid signaling, Konrad Sandhoff produces research that crosses academic boundaries.

His most cited work include:

Ganglioside metabolism. Enzymology, Topology, and regulation. (264 citations)
Partial Enzyme Deficiencies: Residual Activities and the Development of Neurological Disorders (262 citations)
Sphingolipid Activator Protein D (sap-D) Stimulates the Lysosomal Degradation of Ceramide in Vivo (143 citations)

What are the main themes of his work throughout his whole career to date

His work on Biochemistry as part of his general Endoplasmic reticulum study is frequently connected to Membrane, thereby bridging the divide between different branches of science. His Sphingomyelin research extends to the thematically linked field of Biochemistry. He is exploring Enzyme as part of his Hexosaminidase and Lysosome and Enzyme studies. Cell biology is intertwined with Sphingolipid and Intracellular in his research. His Intracellular study frequently involves adjacent topics like Cell biology. Konrad Sandhoff integrates several fields in his works, including Gene and Activator (genetics). Konrad Sandhoff merges many fields, such as Apoptosis and Ceramide, in his writings. He applies his multidisciplinary studies on Ceramide and Apoptosis in his research. His research is interdisciplinary, bridging the disciplines of Activator (genetics) and Receptor.

Konrad Sandhoff most often published in these fields:

Biochemistry (86.49%)
Enzyme (48.65%)
Cell biology (40.54%)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

Christian Eggeling;Christian Ringemann;Rebecca Medda;Günter Schwarzmann.
Nature (2009)

1600 Citations

CD95 signaling via ceramide-rich membrane rafts.

Heike Grassme;Andreas Jekle;Andrea Riehle;Heinz Schwarz.
Journal of Biological Chemistry (2001)

698 Citations

Enhanced insulin sensitivity in mice lacking ganglioside GM3

Tadashi Yamashita;Akira Hashiramoto;Martin Haluzik;Hiroki Mizukami.
Proceedings of the National Academy of Sciences of the United States of America (2003)

559 Citations

Physiology and pathophysiology of sphingolipid metabolism and signaling.

Andrea Huwiler;Thomas Kolter;Josef Pfeilschifter;Konrad Sandhoff.
Biochimica et Biophysica Acta (2000)

550 Citations

Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease.

Kenichi Horinouchi;Shai Erlich;Daniel P. Perl;Klaus Ferlinz.
Nature Genetics (1995)

541 Citations

A vital role for glycosphingolipid synthesis during development and differentiation

Tadashi Yamashita;Ryuichi Wada;Teiji Sasaki;Chuxia Deng.
Proceedings of the National Academy of Sciences of the United States of America (1999)

536 Citations

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

Thomas Kirkegaard;Anke G Roth;Nikolaj H T Petersen;Ajay K Mahalka.
Nature (2010)

496 Citations

Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis

Florian Winau;Stephan Weber;Subash Sad;Juana de Diego.
Immunity (2006)

484 Citations

PRINCIPLES OF LYSOSOMAL MEMBRANE DIGESTION: Stimulation of Sphingolipid Degradation by Sphingolipid Activator Proteins and Anionic Lysosomal Lipids

Thomas Kolter;Konrad Sandhoff.
Annual Review of Cell and Developmental Biology (2005)

483 Citations

Sphingolipids-Their Metabolic Pathways and the Pathobiochemistry of Neurodegenerative Diseases.

Thomas Kolter;Konrad Sandhoff.
Angewandte Chemie (1999)

473 Citations

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Frequent Co-Authors

External Links

Personal Website for Konrad Sandhoff