D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 97 Citations 32,948 347 World Ranking 786 National Ranking 59

Research.com Recognitions

Awards & Achievements

1999 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Human Genetics and Molecular Medicine

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Gene
  • Biochemistry

His primary areas of study are Biochemistry, Cell biology, Sphingolipid, Ceramide and Ganglioside. His study in Sphingolipid Activator Proteins, Glycolipid, Lysosome, Enzyme and Sphingomyelin is carried out as part of his studies in Biochemistry. His Cell biology research incorporates themes from Apoptosis, Cornified envelope, Endocytosis and Transfection.

As a member of one scientific family, he mostly works in the field of Sphingolipid, focusing on Signal transduction and, on occasion, Glycosphingolipid. His Ceramide research also works with subjects such as

  • Lipid signaling which connect with Acid sphingomyelinase,
  • Biosynthesis most often made with reference to Sphingosine. His Ganglioside research is multidisciplinary, relying on both Cell culture, Sialic acid, Sialyltransferase, Central nervous system and Metabolism.

His most cited work include:

  • Direct observation of the nanoscale dynamics of membrane lipids in a living cell (1151 citations)
  • CD95 signaling via ceramide-rich membrane rafts. (537 citations)
  • Enhanced insulin sensitivity in mice lacking ganglioside GM3 (428 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Biochemistry, Cell biology, Sphingolipid, Enzyme and Ceramide. His work on Biochemistry is being expanded to include thematically relevant topics such as Molecular biology. His work carried out in the field of Cell biology brings together such families of science as Endocytic cycle, Endocytosis and Membrane.

His research integrates issues of Lactosylceramide and Lysosome in his study of Sphingolipid. His Ceramide research is multidisciplinary, incorporating perspectives in Stratum corneum, Lipid signaling, Sphingosine, Extracellular and Membrane lipids. His Glycolipid course of study focuses on Golgi apparatus and Vesicle and Biosynthesis.

He most often published in these fields:

  • Biochemistry (58.39%)
  • Cell biology (20.04%)
  • Sphingolipid (20.04%)

What were the highlights of his more recent work (between 2004-2020)?

  • Biochemistry (58.39%)
  • Cell biology (20.04%)
  • Sphingolipid (20.04%)

In recent papers he was focusing on the following fields of study:

Konrad Sandhoff focuses on Biochemistry, Cell biology, Sphingolipid, Ceramide and Membrane lipids. Biochemistry is a component of his Sphingolipid Activator Proteins, Membrane, Lysosome, Catabolism and Glycolipid studies. The study incorporates disciplines such as Ceramide synthase, Endocytosis, Cholesterol and Ganglioside in addition to Cell biology.

His Sphingolipid research includes themes of Biophysics, Lipid metabolism, Ceramidase and Lipidomics. His research integrates issues of Stratum corneum, Lipid signaling, Sphingomyelin, Sphingosine and Golgi apparatus in his study of Ceramide. His Membrane lipids research integrates issues from Lipid bilayer fusion, Liposome, Cell membrane, Enzyme and Lipid bilayer.

Between 2004 and 2020, his most popular works were:

  • Direct observation of the nanoscale dynamics of membrane lipids in a living cell (1151 citations)
  • Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology (357 citations)
  • PRINCIPLES OF LYSOSOMAL MEMBRANE DIGESTION: Stimulation of Sphingolipid Degradation by Sphingolipid Activator Proteins and Anionic Lysosomal Lipids (348 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Biochemistry

His main research concerns Biochemistry, Cell biology, Sphingolipid, Ceramide and Lysosome. His Biochemistry study frequently draws connections between adjacent fields such as Barrier function. His Cell biology study integrates concerns from other disciplines, such as Corneocyte, Sphingolipid Activator Proteins, Keratinocyte, Endocytosis and Cholesterol.

His biological study spans a wide range of topics, including Crystallography, Crystal structure, Lipogenesis and Neurodegeneration. As part of the same scientific family, Konrad Sandhoff usually focuses on Ceramide, concentrating on Lipid signaling and intersecting with Sphingosine, Acid Ceramidase, ENPP7, Phosphatidylserine and Lipid bilayer fusion. His Lysosome study incorporates themes from Lysosomal storage disease, Lipid metabolism and Endosome.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

Christian Eggeling;Christian Ringemann;Rebecca Medda;Günter Schwarzmann.
Nature (2009)

1434 Citations

CD95 signaling via ceramide-rich membrane rafts.

Heike Grassme;Andreas Jekle;Andrea Riehle;Heinz Schwarz.
Journal of Biological Chemistry (2001)

698 Citations

Physiology and pathophysiology of sphingolipid metabolism and signaling.

Andrea Huwiler;Thomas Kolter;Josef Pfeilschifter;Konrad Sandhoff.
Biochimica et Biophysica Acta (2000)

550 Citations

A vital role for glycosphingolipid synthesis during development and differentiation

Tadashi Yamashita;Ryuichi Wada;Teiji Sasaki;Chuxia Deng.
Proceedings of the National Academy of Sciences of the United States of America (1999)

536 Citations

Enhanced insulin sensitivity in mice lacking ganglioside GM3

Tadashi Yamashita;Akira Hashiramoto;Martin Haluzik;Hiroki Mizukami.
Proceedings of the National Academy of Sciences of the United States of America (2003)

529 Citations

Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease.

Kenichi Horinouchi;Shai Erlich;Daniel P. Perl;Klaus Ferlinz.
Nature Genetics (1995)

494 Citations

PRINCIPLES OF LYSOSOMAL MEMBRANE DIGESTION: Stimulation of Sphingolipid Degradation by Sphingolipid Activator Proteins and Anionic Lysosomal Lipids

Thomas Kolter;Konrad Sandhoff.
Annual Review of Cell and Developmental Biology (2005)

483 Citations

Sphingolipids-Their Metabolic Pathways and the Pathobiochemistry of Neurodegenerative Diseases.

Thomas Kolter;Konrad Sandhoff.
Angewandte Chemie (1999)

473 Citations

Apoptotic vesicles crossprime CD8 T cells and protect against tuberculosis

Florian Winau;Stephan Weber;Subash Sad;Juana de Diego.
Immunity (2006)

453 Citations

Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology

Thomas Kirkegaard;Anke G Roth;Nikolaj H T Petersen;Ajay K Mahalka.
Nature (2010)

452 Citations

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