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Biology and Biochemistry
UK
2025

D-Index & Metrics

Biology and Biochemistry

D-Index
97
Citations
33479
World Ranking
1753
National Ranking
113

Research.com Recognitions

  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2018 - Member of Academia Europaea

Overview

Frances M. Platt is affiliated with the University of Oxford in the United Kingdom. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with substantial work in subfields such as Physiology, Molecular Biology, Cell Biology, Epidemiology, and Hematology.

The scientist's work focuses on topics including Lysosomal Storage Disorders Research, Cellular transport and secretion, Calcium signaling and nucleotide metabolism, Glycosylation and Glycoproteins Research, Autoimmune and Inflammatory Disorders Research, Parkinson's Disease Mechanisms and Treatments, and Autophagy in Disease and Therapy.

Frequent publication venues for Frances M. Platt include bioRxiv (Cold Spring Harbor Laboratory) with 17 publications, Molecular Genetics and Metabolism with 6, Scientific Reports with 4, iScience with 3, and PLoS ONE with 3.

Collaborations feature several frequent co-authors, notably David A. Priestman (20 joint publications), Antony Galione (19), Michael Strupp (14), Dawn Shepherd (13), and Nick Platt (12).

Recent papers authored or co-authored by Frances M. Platt include:

  • Current methods to analyze lysosome morphology, positioning, motility and function, 2022, Traffic
  • GM1 Gangliosidosis-A Mini-Review, 2021, Frontiers in Genetics
  • Acetyl-leucine slows disease progression in lysosomal storage disorders, 2020, Brain Communications
  • Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C, 2021, Developmental Cell
  • Brain Pathology in Mucopolysaccharidoses (MPS) Patients with Neurological Forms, 2020, Journal of Clinical Medicine

Frances M. Platt was awarded membership of the Academia Europaea in 2018.

Best Publications

  • bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation.

    Timothy J. McDonnell;Natasha Deane;Frances M. Platt;Gabriel Nunez

  • Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

    B Boland;A Kumar;S Lee;F M Platt

  • Lysosomal storage diseases

    Frances M Platt;Alessandra d'Azzo;Beverly L Davidson;Elizabeth F Neufeld

  • Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis

    T Cox;R Lachmann;C Hollak;J Aerts

  • Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

    Emyr Lloyd-Evans;Anthony J Morgan;Xingxuan He;David A Smith

  • The cell biology of disease: lysosomal storage disorders: the cellular impact of lysosomal dysfunction.

    Frances M. Platt;Barry Boland;Aarnoud C. van der Spoel

  • N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis.

    Frances M. Platt;Gabrielle R. Neises;Raymond A. Dwek;Terry D. Butters

  • Targeting glycosylation as a therapeutic approach

    Raymond A. Dwek;Terry D. Butters;Frances M. Platt;Nicole Zitzmann

  • Lysosomal storage diseases

    Fran Platt

  • Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents

    Nicole Zitzmann;Anand S. Mehta;Sandra Carrouée;Terry D. Butters

  • Prevention of Lysosomal Storage in Tay-Sachs Mice Treated with N-Butyldeoxynojirimycin

    F M Platt;G R Neises;G Reinkensmeier;M J Townsend

  • Infantile-onset symptomatic epilepsy syndrome caused by a homozygous loss-of-function mutation of GM3 synthase.

    Michael A Simpson;Harold Cross;Christos Proukakis;David A Priestman

  • Glycosphingolipid synthesis requires FAPP2 transfer of glucosylceramide

    Giovanni D’Angelo;Elena Polishchuk;Giuseppe Di Tullio;Michele Santoro

  • Common and uncommon pathogenic cascades in lysosomal storage diseases.

    Einat B. Vitner;Frances M. Platt;Anthony H. Futerman

  • Central nervous system inflammation is a hallmark of pathogenesis in mouse models of GM1 and GM2 gangliosidosis.

    M Jeyakumar;R Thomas;E Elliot-Smith;D A Smith

  • Molecular mechanisms of endolysosomal Ca2+ signalling in health and disease

    Anthony J. Morgan;Frances M. Platt;Emyr Lloyd-Evans;Antony Galione

  • Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans

    Carmela De Santo;Mariolina Salio;S. Hajar Masri;Laurel Yong Hwa Lee

  • Inhibition of Glycosphingolipid Biosynthesis: Application to Lysosomal Storage Disorders

    Terry D. Butters;Raymond A. Dwek;Frances M. Platt

  • Sphingolipid lysosomal storage disorders

    Frances M. Platt

  • Chapter 53 – Lysosomal Storage Diseases: Perspectives and Principles

    Edward H. Schuchman;Melissa P. Wasserstein

Frequent Co-Authors

Terry D. Butters
Terry D. Butters University of Oxford
Raymond A. Dwek
Raymond A. Dwek University of Oxford
David Smith
David Smith University of Oxford
Forbes D. Porter
Forbes D. Porter National Institutes of Health
Thomas N. Seyfried
Thomas N. Seyfried Boston College
Antony Galione
Antony Galione University of Oxford
Vincenzo Cerundolo
Vincenzo Cerundolo University of Oxford
Timothy M. Cox
Timothy M. Cox University of Cambridge
Grant C. Churchill
Grant C. Churchill University of Oxford
Michael Strupp
Michael Strupp Ludwig-Maximilians-Universität München

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