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Biology and Biochemistry
UK
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
150
Citations
78885
World Ranking
182
National Ranking
10

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2025 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 1998 - Fellow of the Royal Society, United Kingdom

Overview

Raymond A. Dwek is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple fields, primarily focusing on Medicine, Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Their work involves specialized subfields such as Infectious Diseases, Molecular Biology, Immunology, Organic Chemistry, and Radiology, Nuclear Medicine and Imaging.

The main topics of their research include:

  • SARS-CoV-2 and COVID-19 Research
  • Vaccines and immunoinformatics approaches
  • Interferon and immune responses
  • Monoclonal and Polyclonal Antibodies Research
  • CAR-T cell therapy research
  • Synthesis and Characterization of Heterocyclic Compounds
  • Glycosylation and Glycoproteins Research

Their recent scholarly output includes several publications:

  • COVID-19 therapeutics: Challenges and directions for the future, 2022, Proceedings of the National Academy of Sciences
  • Assessing Antigen Structural Integrity through Glycosylation Analysis of the SARS-CoV-2 Viral Spike, 2021, ACS Central Science
  • Targeting Endoplasmic Reticulum α-Glucosidase I with a Single-Dose Iminosugar Treatment Protects against Lethal Influenza and Dengue Virus Infections, 2020, Journal of Medicinal Chemistry
  • Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago, 2021, Advanced Science
  • Analysis of SARS-CoV-2 spike glycosylation reveals shedding of a vaccine candidate, 2020, bioRxiv (Cold Spring Harbor Laboratory)

The most frequent publication venues for their work encompass:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • ACS Central Science
  • Journal of Medicinal Chemistry
  • Advanced Science

Collaboration is a significant feature of their work, with frequent co-authors including:

  • Nicole Zitzmann
  • Michelle L. Hill
  • Juliane Brun
  • J. L. Kiappes
  • Dominic S. Alonzi

Raymond A. Dwek has been recognized as a Fellow of the Royal Society, United Kingdom, an award granted in 1998.

Best Publications

  • Glycobiology: Toward Understanding the Function of Sugars.

    Raymond A. Dwek

  • Glycosylation and the immune system

    Pauline M. Rudd;Tim Elliott;Peter Cresswell;Ian A. Wilson

  • The Impact of Glycosylation on the Biological Function and Structure of Human Immunoglobulins

    James N. Arnold;Mark R. Wormald;Robert B. Sim;Pauline M. Rudd

  • Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG.

    R. B. Parekh;R. A. Dwek;B. J. Sutton;D. L. Fernandes

  • Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design.

    Erica Ollmann Saphire;Paul W. H. I. Parren;Ralph Pantophlet;Michael B. Zwick

  • Biochemistry and Molecular Biology of Gelatinase B or Matrix Metalloproteinase-9 (MMP-9)

    Philippe E Van den Steen;Bénédicte Dubois;Inge Nelissen;Pauline M Rudd

  • Antibody Domain Exchange Is an Immunological Solution to Carbohydrate Cluster Recognition

    Daniel A. Calarese;Christopher N. Scanlan;Michael B. Zwick;Songpon Deechongkit

  • Concepts and Principles of O-Linked Glycosylation

    Philippe Van den Steen;Pauline M. Rudd;Raymond A. Dwek;Ghislain Opdenakker

  • Glycosylation changes of IgG associated with rheumatoid arthritis can activate complement via the mannose-binding protein.

    Rajneesh Malhotra;Mark R. Wormald;Pauline M. Rudd;Per B. Fischer

  • Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis

    T Cox;R Lachmann;C Hollak;J Aerts

  • Glycosyl-phosphatidylinositol moiety that anchors Trypanosoma brucei variant surface glycoprotein to the membrane

    Michael A. J. Ferguson;Steve W. Homans;Raymond A. Dwek;Thomas W. Rademacher

  • The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120

    Christopher N. Scanlan;Ralph Pantophlet;Mark R. Wormald;Erica Ollmann Saphire

  • Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

    David Peretz;R. Anthony Williamson;Kiotoshi Kaneko;Julie Vergara

  • Use of targeted glycoproteomics to identify serum glycoproteins that correlate with liver cancer in woodchucks and humans.

    Timothy M. Block;Mary Ann Comunale;Melissa Lowman;Laura F. Steel

  • A rapid high-resolution high-performance liquid chromatographic method for separating glycan mixtures and analyzing oligosaccharide profiles.

    Geoffrey R. Guile;Pauline M. Rudd;David R. Wing;Sally B. Prime

  • Glycosylation: heterogeneity and the 3D structure of proteins.

    Pauline M. Rudd;Raymond A. Dwek

  • N-butyldeoxynojirimycin is a novel inhibitor of glycolipid biosynthesis.

    Frances M. Platt;Gabrielle R. Neises;Raymond A. Dwek;Terry D. Butters

  • Targeting glycosylation as a therapeutic approach

    Raymond A. Dwek;Terry D. Butters;Frances M. Platt;Nicole Zitzmann

  • Statistical analysis of the protein environment of N-glycosylation sites: implications for occupancy, structure, and folding.

    Andrei-J. Petrescu;Adina-L. Milac;Stefana M. Petrescu;Raymond A. Dwek

  • The mannose receptor mediates dengue virus infection of macrophages.

    Joanna L Miller;Barend J. M deWet;Luisa Martinez-Pomares;Catherine M Radcliffe

Frequent Co-Authors

Pauline M. Rudd
Pauline M. Rudd University College Cork
Nicole Zitzmann
Nicole Zitzmann University of Oxford
Terry D. Butters
Terry D. Butters University of Oxford
Mark R. Wormald
Mark R. Wormald University of Oxford
Thomas William Rademacher
Thomas William Rademacher University College London
Frances M. Platt
Frances M. Platt University of Oxford
Louise Royle
Louise Royle University College Dublin
Dennis R. Burton
Dennis R. Burton Scripps Research Institute
Timothy M. Block
Timothy M. Block Drexel University
George W. J. Fleet
George W. J. Fleet University of Oxford

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