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Sachiko Tsukamoto

Sachiko Tsukamoto

D-Index & Metrics

Chemistry

D-Index
53
Citations
7653
World Ranking
13304
National Ranking
1014

Overview

Sachiko Tsukamoto is affiliated with Kumamoto University in Japan. Their research spans multiple areas within biochemistry, genetics, and molecular biology as well as medicine.

The main fields of study in which Tsukamoto is active include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these fields, subfields of particular focus include:

  • Molecular Biology
  • Pharmacology
  • Biotechnology
  • Organic Chemistry
  • Oncology

Tsukamoto's work covers a variety of topics, including:

  • Microbial Natural Products and Biosynthesis
  • Marine Sponges and Natural Products
  • Fungal Biology and Applications
  • Ubiquitin and proteasome pathways
  • Chemical Synthesis and Analysis
  • Alkaloids: synthesis and pharmacology
  • Bone Metabolism and Diseases

Frequently publishing in several scientific journals, Tsukamoto has multiple works featured in these venues:

  • Journal of Natural Products
  • Journal of Natural Medicines
  • Bioorganic & Medicinal Chemistry
  • Phytochemistry
  • The Cambridge Structural Database

Selected recent research papers authored or co-authored by Tsukamoto include:

  • "Fungal-derived brevianamide assembly by a stereoselective semipinacolase," 2020, Nature Catalysis
  • "Data Science-Driven Analysis of Substrate-Permissive Diketopiperazine Reverse Prenyltransferase NotF: Applications in Protein Engineering and Cascade Biocatalytic Synthesis of (−)-Eurotiumin A," 2022, Journal of the American Chemical Society
  • "Irpexine, an Isoindolinone Alkaloid Produced by Coculture of Endophytic Fungi, Irpex lacteus and Phaeosphaeria oryzae," 2020, Journal of Natural Products
  • "Flavin-Dependent Monooxygenases NotI and NotI' Mediate Spiro-Oxindole Formation in Biosynthesis of the Notoamides," 2020, ChemBioChem
  • "Isolation, Synthesis, and Structure-Activity Relationship Study on Daphnane and Tigliane Diterpenes as HIV Latency-Reversing Agents," 2022, Journal of Medicinal Chemistry

Throughout their career, Tsukamoto has collaborated frequently with several researchers, including:

  • Yuki Hitora
  • Hikaru Kato
  • Yusaku Sadahiro
  • Ahmed H. El-Desoky
  • Robert M. Williams

Best Publications

  • Notoamides A–D: Prenylated Indole Alkaloids Isolated from a Marine‐Derived Fungus, Aspergillus sp.

    Hikaru Kato;Takushi Yoshida;Takanori Tokue;Yuka Nojiri

  • Ceratinamides A and B: New Antifouling Dibromotyrosine Derivatives from the Marine Sponge Pseudoceratina purpurea

    Sachiko Tsukamoto;Haruko Kato;Hiroshi Hirota;Nobuhiro Fusetani

  • Isolation of antipodal (-)-versicolamide B and notoamides L-N from a marine-derived Aspergillus sp

    Sachiko Tsukamoto;Tetsuro Kawabata;Hikaru Kato;Thomas J. Greshock

  • Notoamides F-K, prenylated indole alkaloids isolated from a marine-derived Aspergillus sp.

    Sachiko Tsukamoto;Hikaru Kato;Masayuki Samizo;Yuka Nojiri

  • Asymmetric total syntheses of (+)- and (−)-versicolamide B and biosynthetic implications

    Kenneth A. Miller;Sachiko Tsukamoto;Robert M. Williams;Robert M. Williams

  • Genome-based characterization of two prenylation steps in the assembly of the stephacidin and notoamide anticancer agents in a marine-derived aspergillus sp.

    Yousong Ding;Jeffrey R. de Wet;James Cavalcoli;Shengying Li

  • Mauritiamine, a new antifouling oroidin dimer from the marine sponge Agelas mauritiana

    Sachiko Tsukamoto;Haruko Kato;Hiroshi Hirota;Nobuhiro Fusetani

  • Natural Diels–Alderases: Elusive and Irresistable

    Kimberly Klas;Sachiko Tsukamoto;David H. Sherman;Robert M. Williams

  • A concise, biomimetic total synthesis of stephacidin A and notoamide B.

    Thomas J. Greshock;Thomas J. Greshock;Alan W. Grubbs;Alan W. Grubbs;Sachiko Tsukamoto;Robert M. Williams;Robert M. Williams

  • Himeic acid A: a new ubiquitin-activating enzyme inhibitor isolated from a marine-derived fungus, Aspergillus sp.

    Sachiko Tsukamoto;Hiroshi Hirota;Misako Imachi;Masahiro Fujimuro

  • Notoamide O, a Structurally Unprecedented Prenylated Indole Alkaloid, and Notoamides P−R from a Marine-Derived Fungus, Aspergillus sp.

    Sachiko Tsukamoto;Hideharu Umaoka;Kohei Yoshikawa;Tsuyoshi Ikeda

  • Anti-obesity compounds in green leaves of Eucommia ulmoides.

    T. Hirata;T. Kobayashi;A. Wada;T. Ueda

  • Onionin A from Allium cepa Inhibits Macrophage Activation

    Mona El-Aasr;Yukio Fujiwara;Motohiro Takeya;Tsuyoshi Ikeda

  • A concise total synthesis of the notoamides C and D.

    Alan W. Grubbs;Gerald D. Artman;Sachiko Tsukamoto;Robert M. Williams;Robert M. Williams

  • Four new bioactive pyrrole-derived alkaloids from the marine sponge Axinella brevistyla.

    Sachiko Tsukamoto;Kazuhiro Tane;Tomihisa Ohta;Shigeki Matsunaga

  • Isolation of cytochrome p450 inhibitors from strawberry fruit, Fragaria ananassa

    Sachiko Tsukamoto;Kyoko Tomise;Maki Aburatani;Hiroyuki Onuki

  • Hexylitaconic acid: a new inhibitor of p53-HDM2 interaction isolated from a marine-derived fungus, Arthrinium sp.

    Sachiko Tsukamoto;Takushi Yoshida;Hidetaka Hosono;Tomihisa Ohta

  • Seven New Polyacetylene Derivatives, Showing Both Potent Metamorphosis-Inducing Activity in Ascidian Larvae and Antifouling Activity Against Barnacle Larvae, from the Marine Sponge Callyspongia truncata

    Sachiko Tsukamoto;Haruko Kato;Hiroshi Hirota;Nobuhiro Fusetani

  • Isolation of notoamide E, a key precursor in the biosynthesis of prenylated indole alkaloids in a marine-derived fungus, Aspergillus sp

    Sachiko Tsukamoto;Hikaru Kato;Thomas J. Greshock;Hiroshi Hirota

  • Ceratinamine: An Unprecedented Antifouling Cyanoformamide from the Marine Sponge Pseudoceratina purpurea.

    Sachiko Tsukamoto;Haruko Kato;Hiroshi Hirota;Nobuhiro Fusetani

  • Structural and stereochemical diversity in prenylated indole alkaloids containing the bicyclo[2.2.2]diazaoctane ring system from marine and terrestrial fungi

    Kimberly R. Klas;Hikaru Kato;Jens C. Frisvad;Fengan Yu

Frequent Co-Authors

Robert M. Williams
Robert M. Williams Colorado State University
Hiroshi Hirota
Hiroshi Hirota Nihon University
David H. Sherman
David H. Sherman University of Michigan–Ann Arbor
Nobuhiro Fusetani
Nobuhiro Fusetani Waseda University
Tomihisa Ohta
Tomihisa Ohta Kanazawa University
Jens Christian Frisvad
Jens Christian Frisvad Technical University of Denmark
Shigeki Matsunaga
Shigeki Matsunaga Kyoto University
Hayato Ishikawa
Hayato Ishikawa Kumamoto University
Hideyoshi Yokosawa
Hideyoshi Yokosawa Hokkaido University
Yukihiko Sugimoto
Yukihiko Sugimoto Kumamoto University

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