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Hayato Ishikawa

Hayato Ishikawa

D-Index & Metrics

Chemistry

D-Index
45
Citations
7851
World Ranking
16393
National Ranking
1292

Overview

Hayato Ishikawa is affiliated with Kumamoto University in Japan. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Chemistry, with significant contributions to Pharmacology, Organic Chemistry, Molecular Biology, Materials Chemistry, and Biochemistry as specialized subfields.

The main topics of research addressed in Ishikawa's work include:

  • Alkaloids: synthesis and pharmacology
  • Traditional and Medicinal Uses of Annonaceae
  • Chemical synthesis and alkaloids
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Natural product bioactivities and synthesis
  • Microbial Natural Products and Biosynthesis

Frequently published venues for Ishikawa's work include:

  • The Cambridge Structural Database
  • Chemistry - A European Journal
  • Chemical and Pharmaceutical Bulletin
  • Journal of Synthetic Organic Chemistry Japan
  • Organic Letters

Frequent coauthors collaborating with Ishikawa are:

  • Mariko Kitajima
  • Jukiya Sakamoto
  • Kenta Rakumitsu
  • Lia Dewi Juliawaty
  • Shinichiro Sawa

Selected papers published by Hayato Ishikawa include:

  • Total Syntheses of (−)-Strictosidine and Related Indole Alkaloid Glycosides, 2020, Angewandte Chemie International Edition
  • Root-knot nematode chemotaxis is positively regulated by l-galactose sidechains of mucilage carbohydrate rhamnogalacturonan-I, 2021, Science Advances
  • 5,6-Dihydro-α-pyrones from the leaves of Cryptocarya pulchinervia (Lauraceae), 2020, Journal of Natural Medicines
  • Bioinspired Transformations Using Strictosidine Aglycones: Divergent Total Syntheses of Monoterpenoid Indole Alkaloids in the Early Stage of Biosynthesis, 2021, Chemistry - A European Journal
  • Epoxyquinophomopsins A and B from endophytic fungus Phomopsis sp. and their activity against tyrosine kinase, 2020, Journal of Natural Medicines

Best Publications

  • High‐Yielding Synthesis of the Anti‐Influenza Neuramidase Inhibitor (−)‐Oseltamivir by Three “One‐Pot” Operations

    Hayato Ishikawa;Takaki Suzuki;Yujiro Hayashi

  • Total synthesis of vinblastine, vincristine, related natural products, and key structural analogues.

    Hayato Ishikawa;David A. Colby;Shigeki Seto;Porino Va

  • Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands.

    Hiromitsu Takayama;Hayato Ishikawa;Mika Kurihara;Mariko Kitajima

  • Asymmetric Michael Reaction of Acetaldehyde Catalyzed by Diphenylprolinol Silyl Ether

    Yujiro Hayashi;Takahiko Itoh;Masahiro Ohkubo;Hayato Ishikawa

  • Diphenylprolinol Silyl Ether as Catalyst of an Asymmetric, Catalytic, and Direct Michael Reaction of Nitroalkanes with α,β-Unsaturated Aldehydes

    Hiroaki Gotoh;Hayato Ishikawa;Yujiro Hayashi

  • Asymmetric aldol reaction of acetaldehyde and isatin derivatives for the total syntheses of ent-convolutamydine E and CPC-1 and a half fragment of madindoline A and B.

    Takahiko Itoh;Hayato Ishikawa;Yujiro Hayashi

  • Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa.

    Kenjiro Matsumoto;Syunji Horie;Hayato Ishikawa;Hiromitsu Takayama

  • A diarylprolinol in an asymmetric, catalytic, and direct crossed-aldol reaction of acetaldehyde.

    Yujiro Hayashi;Takahiko Itoh;Seiji Aratake;Hayato Ishikawa

  • Organocatalyzed Michael Addition of Aldehydes to Nitro Alkenes – Generally Accepted Mechanism Revisited and Revised

    Krystyna Patora-Komisarska;Krystyna Patora-Komisarska;Meryem Benohoud;Hayato Ishikawa;Dieter Seebach

  • Total synthesis of (-)- and ent-(+)-vindoline and related alkaloids

    Hayato Ishikawa;Gregory I. Elliott;Juraj Velcicky;Younggi Choi

  • Direct Coupling of Catharanthine and Vindoline to Provide Vinblastine: Total Synthesis of (+)- and ent-(−)-Vinblastine

    Hayato Ishikawa;David A. Colby;Dale L. Boger

  • Asymmetric Diels–Alder Reactions of α,β‐Unsaturated Aldehydes Catalyzed by a Diarylprolinol Silyl Ether Salt in the Presence of Water

    Yujiro Hayashi;Sampak Samanta;Hiroaki Gotoh;Hayato Ishikawa

  • Oxidative and enantioselective cross-coupling of aldehydes and nitromethane catalyzed by diphenylprolinol silyl ether.

    Yujiro Hayashi;Takahiko Itoh;Hayato Ishikawa

  • High‐Yielding Synthesis of the Anti‐Influenza Neuraminidase Inhibitor (−)‐Oseltamivir by Two “One‐Pot” Sequences

    Hayato Ishikawa;Takaki Suzuki;Hideo Orita;Tadafumi Uchimaru

  • One-Pot High-Yielding Synthesis of the DPP4-Selective Inhibitor ABT-341 by a Four-Component Coupling Mediated by a Diphenylprolinol Silyl Ether†

    Hayato Ishikawa;Masakazu Honma;Yujiro Hayashi

  • Total Synthesis of (−)- and ent-(+)-Vindoline

    Younggi Choi;Hayato Ishikawa;Juraj Velcicky;Gregory I. Elliott

  • Dimerization of indole derivatives with hypervalent iodines(III): a new entry for the concise total synthesis of rac- and meso-chimonanthines

    Hayato Ishikawa;Hiromitsu Takayama;Norio Aimi

  • Direct organocatalytic mannich reaction of acetaldehyde: an improved catalyst and mechanistic insight from a computational study.

    Yujiro Hayashi;Tsubasa Okano;Takahiko Itoh;Tatsuya Urushima

  • Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa.

    Kenjiro Matsumoto;Syunji Horie;Syunji Horie;Hiromitsu Takayama;Hayato Ishikawa

  • Diphenylprolinol silyl ether catalysis in an asymmetric formal carbo [3 + 3] cycloaddition reaction via a domino Michael/Knoevenagel condensation.

    Yujiro Hayashi;Maya Toyoshima;Hiroaki Gotoh;Hayato Ishikawa

  • Intramolecular diels-alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles.

    Gregory I. Elliott;James R. Fuchs;Brian S. J. Blagg;Hayato Ishikawa

Frequent Co-Authors

Yujiro Hayashi
Yujiro Hayashi Tohoku University
Dale L. Boger
Dale L. Boger Scripps Research Institute
Hiromitsu Takayama
Hiromitsu Takayama Chiba University
Hiroyuki Koshino
Hiroyuki Koshino Tokyo University of Agriculture
Mariko Kitajima
Mariko Kitajima Chiba University
Shinichiro Sawa
Shinichiro Sawa Kumamoto University
Hideaki Kakeya
Hideaki Kakeya Kyoto University
Sachiko Tsukamoto
Sachiko Tsukamoto Kumamoto University
Brian S. J. Blagg
Brian S. J. Blagg University of Notre Dame

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