World's Best Scientists 2026 revealed!
Hideaki Kakeya

Hideaki Kakeya

D-Index & Metrics

Chemistry

D-Index
46
Citations
9547
World Ranking
15892
National Ranking
1251

Hideaki Kakeya publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Hideaki Kakeya sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 259 publications — 52nd percentile

52% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Hideaki Kakeya D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hideaki Kakeya sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 46 D-Index — 12th percentile

12% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Hideaki Kakeya is a researcher affiliated with Kyoto University in Japan. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these broad areas, Kakeya's research focuses on specialized subfields including Molecular Biology, Pharmacology, Organic Chemistry, Biochemistry, and Spectroscopy.

Their research topics emphasize areas such as Microbial Natural Products and Biosynthesis, Chemical Synthesis and Analysis, Synthetic Organic Chemistry Methods, and Curcumin's Biomedical Applications. Additional topics include Click Chemistry and Applications, Amino Acid Enzymes and Metabolism, and Marine Sponges and Natural Products.

Hideaki Kakeya has published extensively, with notable recent papers including:

  • "Variational autoencoder-based chemical latent space for large molecular structures with 3D complexity" (2023, Communications Chemistry)
  • "Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy" (2021, The Journal of Antibiotics)
  • "The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice" (2020, Scientific Reports)
  • "Curcumin, an Inhibitor of p300-HAT Activity, Suppresses the Development of Hypertension-Induced Left Ventricular Hypertrophy with Preserved Ejection Fraction in Dahl Rats" (2021, Nutrients)
  • "Cryptic Chemical Communication: Secondary Metabolic Responses Revealed by Microbial Co-culture" (2020, Chemistry - An Asian Journal)

Kakeya frequently publishes in several scientific venues, with the most common being:

  • The Journal of Antibiotics
  • The Journal of Organic Chemistry
  • Chemistry - An Asian Journal
  • ChemBioChem
  • Journal of Natural Products

The scientist collaborates regularly with a group of co-authors, including:

  • Takefumi Kuranaga
  • Hiroaki Ikeda
  • Shinichi Nishimura
  • Chengqian Pan
  • Kensuke Kaneko

Best Publications

  • RNA-Methylation-Dependent RNA Processing Controls the Speed of the Circadian Clock

    Jean-Michel Fustin;Masao Doi;Yoshiaki Yamaguchi;Hayashi Hida

  • Novel mammalian cell cycle inhibitors, spirotryprostatins A and B, produced by Aspergillus fumigatus, which inhibit mammalian cell cycle at G2/M phase☆

    Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada

  • Innovative preparation of curcumin for improved oral bioavailability.

    Hiroki Sasaki;Yoichi Sunagawa;Yoichi Sunagawa;Kenji Takahashi;Atsushi Imaizumi

  • Spirotryprostatin B, a Novel Mammalian Cell Cycle Inhibitor Produced by Aspergillus fumigatus

    Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada

  • Novel Mammalian Cell Cycle Inhibitors, Tryprostatins A, B and Other Diketopiperazines Produced by Aspergillus fumigatus I. Taxonomy, Fermentation, Isolation and Biological Properties

    Cheng-Bin Cui;Hideaki Kakeya;Gen Okada;Rie Onose

  • A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning.

    Naoko Takahashi-Ando;Makoto Kimura;Hideaki Kakeya;Hiroyuki Osada

  • Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. II. Physico-chemical properties and structures.

    Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada

  • Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, produced by a marine fungus.

    Hideaki Kakeya;Isamu Takahashi;Gen Okada;Kiyoshi Isono

  • Cytoxazone: A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp.

    Kakeya H;Morishita M;Koshino H;Morita Ti

  • Azaspirene: a novel angiogenesis inhibitor containing a 1-oxa-7-azaspiro[4.4]non-2-ene-4,6-dione skeleton produced by the fungus Neosartorya sp.

    Yukihiro Asami;Hideaki Kakeya;Rie Onose;Arika Yoshida

  • Biotransformation of the Mycotoxin, Zearalenone, to a Non-estrogenic Compound by a Fungal Strain of Clonostachys sp.

    Hideaki Kakeya;Naoko Takahashi-Ando;Makoto Kimura;Rie Onose

  • Isolation and Biological Activity of a Novel Cytokine Modulator, Cytoxazone

    Hideaki Kakeya;Masayuki Morishita;Kimie Kobinata;Michiyo Osono

  • Marine antifungal theonellamides target 3β-hydroxysterol to activate Rho1 signaling

    Shinichi Nishimura;Yuko Arita;Miyuki Honda;Kunihiko Iwamoto

  • Microbial hydrolysis as a potent method for the preparation of optically active nitriles, amides and carboxylic acids

    Hideaki Kakeya;Naoko Sakai;Takeshi Sugai;Hiromichi Ohta

  • Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. I. Taxonomy, isolation, and characterization.

    Masaya Imoto;Hideaki Kakeya;Tsutomu Sawa;Chigusa Hayashi

  • Epolactaene binds human Hsp60 Cys442 resulting in the inhibition of chaperone activity.

    Yoko Nagumo;Hideaki Kakeya;Mitsuru Shoji;Yujiro Hayashi

  • Neuritogenic Effect of Epolactaene Derivatives on Human Neuroblastoma Cells Which Lack High-Affinity Nerve Growth Factor Receptors

    Hideaki Kakeya;Chizuko Onozawa;Masakazu Sato;Koshi Arai

  • Epoxyquinol A, a highly functionalized pentaketide dimer with antiangiogenic activity isolated from fungal metabolites.

    Hideaki Kakeya;Rie Onose;Hiroyuki Koshino;Arika Yoshida

  • Total synthesis of (+)-epoxyquinols A and B.

    Mitsuru Shoji;Junichiro Yamaguchi;Hideaki Kakeya;Hiroyuki Osada

  • Caspase-mediated Activation of a 36-kDa Myelin Basic Protein Kinase during Anticancer Drug-induced Apoptosis

    Hideaki Kakeya;Rie Onose;Hiroyuki Osada

  • Tryprostatins A and B, Novel Mammalian Cell Cycle Inhibitors Produced by Aspergillus fumigatus.

    C.‐B. Cui;H. Kakeya;G. Okada;R. Onose

Frequent Co-Authors

Yujiro Hayashi
Yujiro Hayashi Tohoku University
Junichiro Yamaguchi
Junichiro Yamaguchi Waseda University
Minoru Yoshida
Minoru Yoshida University of Tokyo
Yoshiharu Iwabuchi
Yoshiharu Iwabuchi Tohoku University
Hiroyuki Koshino
Hiroyuki Koshino Tokyo University of Agriculture
Shinya Oishi
Shinya Oishi Kyoto University
Hiromichi Ohta
Hiromichi Ohta Hokkaido University
Kazuo Umezawa
Kazuo Umezawa Aichi Medical University

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