D-Index & Metrics Best Publications
Hiroyuki Osada

Hiroyuki Osada

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 85 Citations 23,006 667 World Ranking 2039 National Ranking 126

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Biochemistry

Hiroyuki Osada spends much of his time researching Biochemistry, Cell biology, Stereochemistry, In vitro and Molecular biology. His Biochemistry and Mutant, Enzyme, Protein tyrosine phosphatase, Gene and Biosynthesis investigations all form part of his Biochemistry research activities. Hiroyuki Osada works mostly in the field of Cell biology, limiting it down to topics relating to Gene knockdown and, in certain cases, Regulation of gene expression and Signal transduction, as a part of the same area of interest.

As a part of the same scientific family, he mostly works in the field of Stereochemistry, focusing on Aspergillus fumigatus and, on occasion, Carbon-13 NMR and Two-dimensional nuclear magnetic resonance spectroscopy. His In vitro study combines topics from a wide range of disciplines, such as Cell culture, Cell growth and Microbiology. His Molecular biology research is multidisciplinary, incorporating elements of Cell and Mitochondrion.

His most cited work include:

  • Purification and characterization of a newly identified growth factor specific for epithelial cells (766 citations)
  • In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation. (579 citations)
  • Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL). (462 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Biochemistry, Stereochemistry, Cell biology, Molecular biology and Streptomyces. His work in Biochemistry is not limited to one particular discipline; it also encompasses Cell culture. His Stereochemistry study incorporates themes from Structure–activity relationship and Ring.

The concepts of his Cell biology study are interwoven with issues in Cancer cell, Apoptosis and Mutant. Specifically, his work in Streptomyces is concerned with the study of Streptomycetaceae. Streptomycetaceae is a subfield of Actinomycetales that he studies.

He most often published in these fields:

  • Biochemistry (34.07%)
  • Stereochemistry (22.90%)
  • Cell biology (16.14%)

What were the highlights of his more recent work (between 2015-2021)?

  • Biochemistry (34.07%)
  • Cell biology (16.14%)
  • Stereochemistry (22.90%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Biochemistry, Cell biology, Stereochemistry, Biosynthesis and Computational biology. His Biochemistry study frequently draws connections between adjacent fields such as Streptomyces. His studies deal with areas such as Cancer cell, Arabidopsis, Mutant and Small molecule as well as Cell biology.

His Stereochemistry research integrates issues from Cycloaddition and Stereoisomerism. His biological study spans a wide range of topics, including Amino acid and Antiparasitic. His Computational biology research incorporates elements of Genetic interaction, Biological process, Mode of action and Drug discovery.

Between 2015 and 2021, his most popular works were:

  • Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival. (59 citations)
  • Potential Role of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages (59 citations)
  • Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides. (52 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Hiroyuki Osada mostly deals with Biochemistry, Cell biology, Biosynthesis, Stereochemistry and Computational biology. His work carried out in the field of Biochemistry brings together such families of science as Cancer cell and Streptomyces. His study looks at the relationship between Cancer cell and topics such as Proteome, which overlap with Cell culture.

The various areas that he examines in his Cell biology study include Mutant and Mechanism of action. Hiroyuki Osada has included themes like Strictosidine, Decane and Enzyme in his Stereochemistry study. His Computational biology research incorporates themes from Small Molecule Libraries, Bioinformatics, Drug discovery, Gene and Biological process.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Purification and characterization of a newly identified growth factor specific for epithelial cells

Jeffrey S. Rubin;Hiroyuki Osada;Paul W. Finch;William G. Taylor.
Proceedings of the National Academy of Sciences of the United States of America (1989)

1157 Citations

In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation.

Akihisa Matsuyama;Tadahiro Shimazu;Yuko Sumida;Akiko Saito.
The EMBO Journal (2002)

794 Citations

Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL).

Masahito Matsumoto;Tatsuhiko Sudo;Tamio Saito;Hiroyuki Osada.
Journal of Biological Chemistry (2000)

705 Citations

M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFβ-TrCP

Nobumoto Watanabe;Harumi Arai;Yoshifumi Nishihara;Makoto Taniguchi.
Proceedings of the National Academy of Sciences of the United States of America (2004)

601 Citations

Spirotryprostatin B, a Novel Mammalian Cell Cycle Inhibitor Produced by Aspergillus fumigatus

Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada.
The Journal of Antibiotics (1996)

329 Citations

Tryprostatin A, a specific and novel inhibitor of microtubule assembly.

Takeo Usui;Masuo Kondoh;Cheng-Bin Cui;Tadanori Mayumi.
Biochemical Journal (1998)

267 Citations

Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis.

Vladislav Temkin;Qiquan Huang;Hongtao Liu;Hiroyuki Osada.
Molecular and Cellular Biology (2006)

266 Citations

Novel mammalian cell cycle inhibitors, spirotryprostatins A and B, produced by Aspergillus fumigatus, which inhibit mammalian cell cycle at G2/M phase☆

Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada.
Tetrahedron (1997)

264 Citations

Novel Mammalian Cell Cycle Inhibitors, Tryprostatins A, B and Other Diketopiperazines Produced by Aspergillus fumigatus I. Taxonomy, Fermentation, Isolation and Biological Properties

Cheng-Bin Cui;Hideaki Kakeya;Gen Okada;Rie Onose.
The Journal of Antibiotics (1996)

264 Citations

Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways

Nobumoto Watanabe;Harumi Arai;Jun-ichi Iwasaki;Masaaki Shiina.
Proceedings of the National Academy of Sciences of the United States of America (2005)

262 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Hiroyuki Osada

Herbert Waldmann

Herbert Waldmann

Max Planck Society

Publications: 60

Minoru Yoshida

Minoru Yoshida

University of Tokyo

Publications: 51

Shu-Ming Li

Shu-Ming Li

Philipp University of Marburg

Publications: 37

Israel Vlodavsky

Israel Vlodavsky

Technion – Israel Institute of Technology

Publications: 32

Stuart A. Aaronson

Stuart A. Aaronson

Icahn School of Medicine at Mount Sinai

Publications: 32

Jeffrey S. Rubin

Jeffrey S. Rubin

National Institutes of Health

Publications: 30

Michele Pagano

Michele Pagano

Howard Hughes Medical Institute

Publications: 28

Kazuo Shin-ya

Kazuo Shin-ya

National Institute of Advanced Industrial Science and Technology

Publications: 25

Jiake Xu

Jiake Xu

University of Western Australia

Publications: 24

Neta Ilan

Neta Ilan

Technion – Israel Institute of Technology

Publications: 23

Christian Hertweck

Christian Hertweck

Friedrich Schiller University Jena

Publications: 22

Guido Kroemer

Guido Kroemer

Sorbonne University

Publications: 22

Yi Tang

Yi Tang

University of California, Los Angeles

Publications: 22

Hideaki Oikawa

Hideaki Oikawa

Hokkaido University

Publications: 21

Ikuro Abe

Ikuro Abe

University of Tokyo

Publications: 21

Nancy P. Keller

Nancy P. Keller

University of Wisconsin–Madison

Publications: 20

Trending Scientists

Antonio Fernández-Caballero

Antonio Fernández-Caballero

University of Castilla-La Mancha

Koichi Komatsu

Koichi Komatsu

Kyoto University

Vincenzo Barone

Vincenzo Barone

Scuola Normale Superiore di Pisa

Bing Su

Bing Su

Chinese Academy of Sciences

Maria Ogrzewalska

Maria Ogrzewalska

Oswaldo Cruz Foundation

Chia-Ming Chu

Chia-Ming Chu

Memorial Hospital of South Bend

Juan José Lasarte

Juan José Lasarte

University of Navarra

Barbara Bottazzi

Barbara Bottazzi

Humanitas University

Yvonne Barnes-Holmes

Yvonne Barnes-Holmes

Ireland Consulting Psychologists Ltd

Marcus J.H. Huibers

Marcus J.H. Huibers

Vrije Universiteit Amsterdam

Alan L. Peterson

Alan L. Peterson

The University of Texas Health Science Center at San Antonio

Morten A. Karsdal

Morten A. Karsdal

University of Southern Denmark

Andrew M. Jones

Andrew M. Jones

University of Liverpool

D. Dunbar Ivy

D. Dunbar Ivy

University of Colorado Denver

David W. Hedley

David W. Hedley

Princess Margaret Cancer Centre

Paul Corcoran

Paul Corcoran

University College Cork

Something went wrong. Please try again later.