Hiroyuki Osada spends much of his time researching Biochemistry, Cell biology, Stereochemistry, In vitro and Molecular biology. His Biochemistry and Mutant, Enzyme, Protein tyrosine phosphatase, Gene and Biosynthesis investigations all form part of his Biochemistry research activities. Hiroyuki Osada works mostly in the field of Cell biology, limiting it down to topics relating to Gene knockdown and, in certain cases, Regulation of gene expression and Signal transduction, as a part of the same area of interest.
As a part of the same scientific family, he mostly works in the field of Stereochemistry, focusing on Aspergillus fumigatus and, on occasion, Carbon-13 NMR and Two-dimensional nuclear magnetic resonance spectroscopy. His In vitro study combines topics from a wide range of disciplines, such as Cell culture, Cell growth and Microbiology. His Molecular biology research is multidisciplinary, incorporating elements of Cell and Mitochondrion.
His scientific interests lie mostly in Biochemistry, Stereochemistry, Cell biology, Molecular biology and Streptomyces. His work in Biochemistry is not limited to one particular discipline; it also encompasses Cell culture. His Stereochemistry study incorporates themes from Structure–activity relationship and Ring.
The concepts of his Cell biology study are interwoven with issues in Cancer cell, Apoptosis and Mutant. Specifically, his work in Streptomyces is concerned with the study of Streptomycetaceae. Streptomycetaceae is a subfield of Actinomycetales that he studies.
His primary areas of investigation include Biochemistry, Cell biology, Stereochemistry, Biosynthesis and Computational biology. His Biochemistry study frequently draws connections between adjacent fields such as Streptomyces. His studies deal with areas such as Cancer cell, Arabidopsis, Mutant and Small molecule as well as Cell biology.
His Stereochemistry research integrates issues from Cycloaddition and Stereoisomerism. His biological study spans a wide range of topics, including Amino acid and Antiparasitic. His Computational biology research incorporates elements of Genetic interaction, Biological process, Mode of action and Drug discovery.
Hiroyuki Osada mostly deals with Biochemistry, Cell biology, Biosynthesis, Stereochemistry and Computational biology. His work carried out in the field of Biochemistry brings together such families of science as Cancer cell and Streptomyces. His study looks at the relationship between Cancer cell and topics such as Proteome, which overlap with Cell culture.
The various areas that he examines in his Cell biology study include Mutant and Mechanism of action. Hiroyuki Osada has included themes like Strictosidine, Decane and Enzyme in his Stereochemistry study. His Computational biology research incorporates themes from Small Molecule Libraries, Bioinformatics, Drug discovery, Gene and Biological process.
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Purification and characterization of a newly identified growth factor specific for epithelial cells
Jeffrey S. Rubin;Hiroyuki Osada;Paul W. Finch;William G. Taylor.
Proceedings of the National Academy of Sciences of the United States of America (1989)
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation.
Akihisa Matsuyama;Tadahiro Shimazu;Yuko Sumida;Akiko Saito.
The EMBO Journal (2002)
Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL).
Masahito Matsumoto;Tatsuhiko Sudo;Tamio Saito;Hiroyuki Osada.
Journal of Biological Chemistry (2000)
M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFβ-TrCP
Nobumoto Watanabe;Harumi Arai;Yoshifumi Nishihara;Makoto Taniguchi.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Spirotryprostatin B, a Novel Mammalian Cell Cycle Inhibitor Produced by Aspergillus fumigatus
Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada.
The Journal of Antibiotics (1996)
Tryprostatin A, a specific and novel inhibitor of microtubule assembly.
Takeo Usui;Masuo Kondoh;Cheng-Bin Cui;Tadanori Mayumi.
Biochemical Journal (1998)
Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis.
Vladislav Temkin;Qiquan Huang;Hongtao Liu;Hiroyuki Osada.
Molecular and Cellular Biology (2006)
Novel mammalian cell cycle inhibitors, spirotryprostatins A and B, produced by Aspergillus fumigatus, which inhibit mammalian cell cycle at G2/M phase☆
Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada.
Tetrahedron (1997)
Novel Mammalian Cell Cycle Inhibitors, Tryprostatins A, B and Other Diketopiperazines Produced by Aspergillus fumigatus I. Taxonomy, Fermentation, Isolation and Biological Properties
Cheng-Bin Cui;Hideaki Kakeya;Gen Okada;Rie Onose.
The Journal of Antibiotics (1996)
Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways
Nobumoto Watanabe;Harumi Arai;Jun-ichi Iwasaki;Masaaki Shiina.
Proceedings of the National Academy of Sciences of the United States of America (2005)
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