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Hiroyuki Osada

Hiroyuki Osada

RIKEN
Japan

D-Index & Metrics

Biology and Biochemistry

D-Index
90
Citations
27820
World Ranking
2446
National Ranking
150

Hiroyuki Osada publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Hiroyuki Osada sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 725 publications — 98th percentile

98% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Hiroyuki Osada D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroyuki Osada sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 90 D-Index — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Hiroyuki Osada is affiliated with RIKEN in Japan and has a research focus centered on biochemistry, genetics, and molecular biology, with significant contributions to medicine. Their work spans diverse subfields including molecular biology, pharmacology, plant science, organic chemistry, and cancer research.

The research topics engaged by Osada encompass microbial natural products and biosynthesis, fungal biology and applications, plant biochemistry and biosynthesis, plant-microbe interactions and immunity, ubiquitin and proteasome pathways, as well as cancer, hypoxia, metabolism, and cancer therapeutics and mechanisms.

Frequent co-authors collaborating with Osada include Yushi Futamura, Toshihiko Nogawa, Yasumitsu Kondoh, Shunji Takahashi, and Makoto Muroi.

The scientist often publishes in venues such as Bioscience Biotechnology and Biochemistry, The Journal of Antibiotics, ACS Chemical Biology, bioRxiv (Cold Spring Harbor Laboratory), and Nature Communications.

Notable recent papers by Osada include:

  • "Gastrodin From Gastrodia elata Enhances Cognitive Function and Neuroprotection of AD Mice via the Regulation of Gut Microbiota Composition and Inhibition of Neuron Inflammation" (2022) Frontiers in Pharmacology
  • "Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1)" (2022) ACS Chemical Biology
  • "BIONIC: biological network integration using convolutions" (2022) Nature Methods
  • "Targeting fungal membrane homeostasis with imidazopyrazoindoles impairs azole resistance and biofilm formation" (2022) Nature Communications
  • "Peanut skin extract ameliorates the symptoms of type 2 diabetes mellitus in mice by alleviating inflammation and maintaining gut microbiota homeostasis" (2020) Aging

Best Publications

  • Purification and characterization of a newly identified growth factor specific for epithelial cells

    Jeffrey S. Rubin;Hiroyuki Osada;Paul W. Finch;William G. Taylor

  • In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation.

    Akihisa Matsuyama;Tadahiro Shimazu;Yuko Sumida;Akiko Saito

  • Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL).

    Masahito Matsumoto;Tatsuhiko Sudo;Tamio Saito;Hiroyuki Osada

  • M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFβ-TrCP

    Nobumoto Watanabe;Harumi Arai;Yoshifumi Nishihara;Makoto Taniguchi

  • Novel mammalian cell cycle inhibitors, spirotryprostatins A and B, produced by Aspergillus fumigatus, which inhibit mammalian cell cycle at G2/M phase☆

    Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada

  • Spirotryprostatin B, a Novel Mammalian Cell Cycle Inhibitor Produced by Aspergillus fumigatus

    Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada

  • Novel Mammalian Cell Cycle Inhibitors, Tryprostatins A, B and Other Diketopiperazines Produced by Aspergillus fumigatus I. Taxonomy, Fermentation, Isolation and Biological Properties

    Cheng-Bin Cui;Hideaki Kakeya;Gen Okada;Rie Onose

  • Tryprostatin A, a specific and novel inhibitor of microtubule assembly.

    Takeo Usui;Masuo Kondoh;Cheng-Bin Cui;Tadanori Mayumi

  • Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways

    Nobumoto Watanabe;Harumi Arai;Jun-ichi Iwasaki;Masaaki Shiina

  • A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning.

    Naoko Takahashi-Ando;Makoto Kimura;Hideaki Kakeya;Hiroyuki Osada

  • Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis.

    Vladislav Temkin;Qiquan Huang;Hongtao Liu;Hiroyuki Osada

  • Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. II. Physico-chemical properties and structures.

    Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada

  • Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions.

    Naoki Kanoh;Saori Kumashiro;Siro Simizu;Yasumitsu Kondoh

  • Tryprostatins A and B, novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus

    Cheng-Bin Cui;Hideaki Kakeya;Gen Okada;Rie Onose

  • RK-682, a potent inhibitor of tyrosine phosphatase, arrested the mammalian cell cycle progression at G1phase

    Takuya Hamaguchi;Tatsuhiko Sudo;Hiroyuki Osada

  • Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, produced by a marine fungus.

    Hideaki Kakeya;Isamu Takahashi;Gen Okada;Kiyoshi Isono

  • Cytoxazone: A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp.

    Kakeya H;Morishita M;Koshino H;Morita Ti

  • Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes

    Subramaniam Ganesh;Kishan Lal Agarwala;Kazunori Ueda;Takumi Akagi

  • Suppression of Apoptosis by Cyclophilin D via Stabilization of Hexokinase II Mitochondrial Binding in Cancer Cells

    Kiyotaka Machida;Yoshihiro Ohta;Hiroyuki Osada

  • The Multidrug Resistance-associated Protein (MRP) Subfamily (Yrs1/Yor1) of Saccharomyces cerevisiae Is Important for the Tolerance to a Broad Range of Organic Anions

    Zhifeng Cui;Dai Hirata;Eiko Tsuchiya;Hiroyuki Osada

Frequent Co-Authors

Hideaki Kakeya
Hideaki Kakeya Kyoto University
Hiroyuki Koshino
Hiroyuki Koshino Tokyo University of Agriculture
Yujiro Hayashi
Yujiro Hayashi Tohoku University
Minoru Yoshida
Minoru Yoshida University of Tokyo
Junichiro Yamaguchi
Junichiro Yamaguchi Waseda University
Herbert Waldmann
Herbert Waldmann Max Planck Society
Hiroshi Hirota
Hiroshi Hirota Nihon University
Naoshi Dohmae
Naoshi Dohmae RIKEN
Isamu Yamaguchi
Isamu Yamaguchi RIKEN
Daisuke Hashizume
Daisuke Hashizume RIKEN

External Links

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Best Scientists Citing Hiroyuki Osada

Herbert Waldmann

Herbert Waldmann

Max Planck Society

Publications: 60

Minoru Yoshida

Minoru Yoshida

University of Tokyo

Publications: 51

Shu-Ming Li

Shu-Ming Li

Philipp University of Marburg

Publications: 37

Stuart A. Aaronson

Stuart A. Aaronson

Icahn School of Medicine at Mount Sinai

Publications: 32

Israel Vlodavsky

Israel Vlodavsky

Technion – Israel Institute of Technology

Publications: 32

Jeffrey S. Rubin

Jeffrey S. Rubin

National Institutes of Health

Publications: 30

Michele Pagano

Michele Pagano

New York University

Publications: 28

Kazuo Shin-ya

Kazuo Shin-ya

National Institute of Advanced Industrial Science and Technology

Publications: 25

Jiake Xu

Jiake Xu

University of Western Australia

Publications: 24

Neta Ilan

Neta Ilan

Technion – Israel Institute of Technology

Publications: 23

Guido Kroemer

Guido Kroemer

Université Paris Cité

Publications: 22

Yi Tang

Yi Tang

University of California, Los Angeles

Publications: 22

Christian Hertweck

Christian Hertweck

Friedrich Schiller University Jena

Publications: 22

Ikuro Abe

Ikuro Abe

University of Tokyo

Publications: 21

Hideaki Oikawa

Hideaki Oikawa

Hokkaido University

Publications: 21

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Sabine Werner

ETH Zurich

Publications: 20

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