Hiroyuki Osada

Overview

Best Publications

• Purification and characterization of a newly identified growth factor specific for epithelial cells

  Jeffrey S. Rubin;Hiroyuki Osada;Paul W. Finch;William G. Taylor

  1169
  Citations

• In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation.

  Akihisa Matsuyama;Tadahiro Shimazu;Yuko Sumida;Akiko Saito

  856
  Citations

• Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL).

  Masahito Matsumoto;Tatsuhiko Sudo;Tamio Saito;Hiroyuki Osada

  653
  Citations

• M-phase kinases induce phospho-dependent ubiquitination of somatic Wee1 by SCFβ-TrCP

  Nobumoto Watanabe;Harumi Arai;Yoshifumi Nishihara;Makoto Taniguchi

  612
  Citations

• Novel mammalian cell cycle inhibitors, spirotryprostatins A and B, produced by Aspergillus fumigatus, which inhibit mammalian cell cycle at G2/M phase☆

  Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada

  586
  Citations

• Spirotryprostatin B, a Novel Mammalian Cell Cycle Inhibitor Produced by Aspergillus fumigatus

  Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada

  413
  Citations

• Novel Mammalian Cell Cycle Inhibitors, Tryprostatins A, B and Other Diketopiperazines Produced by Aspergillus fumigatus I. Taxonomy, Fermentation, Isolation and Biological Properties

  Cheng-Bin Cui;Hideaki Kakeya;Gen Okada;Rie Onose

  299
  Citations

• Tryprostatin A, a specific and novel inhibitor of microtubule assembly.

  Takeo Usui;Masuo Kondoh;Cheng-Bin Cui;Tadanori Mayumi

  284
  Citations

• Cyclin-dependent kinase (CDK) phosphorylation destabilizes somatic Wee1 via multiple pathways

  Nobumoto Watanabe;Harumi Arai;Jun-ichi Iwasaki;Masaaki Shiina

  274
  Citations

• A novel lactonohydrolase responsible for the detoxification of zearalenone: enzyme purification and gene cloning.

  Naoko Takahashi-Ando;Makoto Kimura;Hideaki Kakeya;Hiroyuki Osada

  253
  Citations

• Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis.

  Vladislav Temkin;Qiquan Huang;Hongtao Liu;Hiroyuki Osada

  250
  Citations

• Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. II. Physico-chemical properties and structures.

  Cheng-Bin Cui;Hideaki Kakeya;Hiroyuki Osada

  224
  Citations

• Immobilization of natural products on glass slides by using a photoaffinity reaction and the detection of protein-small-molecule interactions.

  Naoki Kanoh;Saori Kumashiro;Siro Simizu;Yasumitsu Kondoh

  212
  Citations

• Tryprostatins A and B, novel mammalian cell cycle inhibitors produced by Aspergillus fumigatus

  Cheng-Bin Cui;Hideaki Kakeya;Gen Okada;Rie Onose

  199
  Citations

• RK-682, a potent inhibitor of tyrosine phosphatase, arrested the mammalian cell cycle progression at G1phase

  Takuya Hamaguchi;Tatsuhiko Sudo;Hiroyuki Osada

  194
  Citations

• Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, produced by a marine fungus.

  Hideaki Kakeya;Isamu Takahashi;Gen Okada;Kiyoshi Isono

  183
  Citations

• Cytoxazone: A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp.

  Kakeya H;Morishita M;Koshino H;Morita Ti

  181
  Citations

• Laforin, defective in the progressive myoclonus epilepsy of Lafora type, is a dual-specificity phosphatase associated with polyribosomes

  Subramaniam Ganesh;Kishan Lal Agarwala;Kazunori Ueda;Takumi Akagi

  181
  Citations

• Suppression of Apoptosis by Cyclophilin D via Stabilization of Hexokinase II Mitochondrial Binding in Cancer Cells

  Kiyotaka Machida;Yoshihiro Ohta;Hiroyuki Osada

  180
  Citations

• The Multidrug Resistance-associated Protein (MRP) Subfamily (Yrs1/Yor1) of Saccharomyces cerevisiae Is Important for the Tolerance to a Broad Range of Organic Anions

  Zhifeng Cui;Dai Hirata;Eiko Tsuchiya;Hiroyuki Osada

  177
  Citations