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Biology and Biochemistry

D-Index
83
Citations
24894
World Ranking
3495
National Ranking
1757

Overview

Jeffrey S. Rubin is affiliated with the National Institutes of Health in the United States and has contributed to research primarily in the field of Medicine, with a focus on Immunology, Hematology, Pulmonary and Respiratory Medicine, Genetics, and Radiology, Nuclear Medicine and Imaging.

Their recent publications include:

  • A homogeneous SIRPα-CD47 cell-based, ligand-binding assay: Utility for small molecule drug development in immuno-oncology (2020, PLoS ONE)
  • A Phase 1 Single Dose Escalation Study of Palifermin Administered Pre-Transplant Conditioning in Subjects Undergoing Matched Unrelated Donor Allogeneic Hematopoietic Stem Cell Transplantation (2020, Blood)
  • Hepatocyte Growth Factor (2023, Zenodo [CERN European Organization for Nuclear Research])
  • Phase 1/2 study of high-dose palifermin for GVHD prophylaxis in patients undergoing HLA-matched unrelated donor HCT (2025, Blood)
  • Wnt/PKC Signaling Inhibits Sensory Hair Cell Formation in the Developing Mammalian Cochlea (2025, Cells)

Their research covers several main topics, including:

  • Oral health in cancer treatment
  • Hematopoietic Stem Cell Transplantation
  • Mesenchymal stem cell research
  • Corneal Surgery and Treatments
  • Phagocytosis and Immune Regulation
  • Immunotherapy and Immune Responses
  • Immune cells in cancer

Jeffrey S. Rubin frequently collaborates with other researchers, notably:

  • Alen Ostojić
  • Noa G. Holtzman
  • Lauren M. Curtis
  • Theo Heller
  • Steven Z. Pavletic

Their work has been published in several venues multiple times, with the principal journals and repositories being:

  • Clio s Psyche (5 publications)
  • Blood (3 publications)
  • PLoS ONE (1 publication)
  • Cells (1 publication)
  • Zenodo (CERN European Organization for Nuclear Research) (1 publication)

Overall, the research contributions of Jeffrey S. Rubin align closely with advances in immunology and hematology, particularly as they relate to stem cell transplantation and immuno-oncology. This body of work reflects ongoing engagement with both clinical and experimental approaches focusing on immune system regulation, cancer treatment-related oral health, and novel cellular therapies.

Best Publications

  • Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product

    D. P. Bottaro;J. S. Rubin;D. L. Faletto;A. M.-L. Chan

  • Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth

    Paul W. Finch;Jeffrey S. Rubin;Toru Miki;Dina Ron

  • Purification and characterization of a newly identified growth factor specific for epithelial cells

    Jeffrey S. Rubin;Hiroyuki Osada;Paul W. Finch;William G. Taylor

  • Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast.

    Christina Scheel;Elinor Ng Eaton;Sophia Hsin Jung Li;Christine L. Chaffer

  • A BROAD-SPECTRUM HUMAN LUNG FIBROBLAST-DERIVED MITOGEN IS A VARIANT OF HEPATOCYTE GROWTH FACTOR

    J S Rubin;A M Chan;D P Bottaro;W H Burgess

  • Expression cDNA cloning of the KGF receptor by creation of a transforming autocrine loop.

    Toru Miki;Timothy P. Fleming;Donald P. Bottaro;Jeffrey S. Rubin

  • Purification and Molecular Cloning of a Secreted, Frizzled-Related Antagonist of Wnt Action

    Finch Pw;He X;Kelley Mj;Uren A

  • Secreted Frizzled-related Protein-1 Binds Directly to Wingless and Is a Biphasic Modulator of Wnt Signaling *

    Aykut Üren;Frieda Reichsman;Vasiliki Anest;William G. Taylor

  • Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast-conditioned medium.

    R J Panos;J S Rubin;K G Csaky;S A Aaronson

  • Akt participation in the Wnt signaling pathway through Dishevelled.

    Shinya Fukumoto;Chung-Ming Hsieh;Koji Maemura;Matthew D. Layne

  • Keratinocyte growth factor.

    J S Rubin;D P Bottaro;M Chedid;T Miki

  • Pattern of keratinocyte growth factor and keratinocyte growth factor receptor expression during mouse fetal development suggests a role in mediating morphogenetic mesenchymal‐epithelial interactions

    Paul W. Finch;Gerald R. Cunha;Jeffrey S. Rubin;Jane Wong

  • Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product

    Jeffrey S. Rubin;Donald P. Bottaro;Stuart A. Aaronson

  • Intratracheal instillation of keratinocyte growth factor decreases hyperoxia-induced mortality in rats.

    R J Panos;P M Bak;W S Simonet;J S Rubin

  • Keratinocyte Growth Factor⧸Fibroblast Growth Factor 7, a Homeostatic Factor with Therapeutic Potential for Epithelial Protection and Repair

    Paul W Finch;Jeffrey S Rubin

  • Regulation of keratinocyte growth factor gene expression by interleukin 1.

    M Chedid;J S Rubin;K G Csaky;S A Aaronson

  • Human keratinocyte growth factor activity on proliferation and differentiation of human keratinocytes: differentiation response distinguishes KGF from EGF family.

    C. Marchese;J. Rubin;D. Ron;A. Faggioni

  • Rapid, Wnt-Induced Changes in GSK3β Associations that Regulate β-Catenin Stabilization Are Mediated by Gα Proteins

    Xunxian Liu;Jeffrey S. Rubin;Alan R. Kimmel

  • Identification of a competitive HGF antagonist encoded by an alternative transcript.

    Andrew M.-L. Chan;Jeffrey S. Rubin;Donald P. Bottaro;David W. Hirschfield

  • Characterization of the receptor for keratinocyte growth factor. Evidence for multiple fibroblast growth factor receptors.

    D P Bottaro;J S Rubin;D Ron;P W Finch

Frequent Co-Authors

Stuart A. Aaronson
Stuart A. Aaronson Icahn School of Medicine at Mount Sinai
Donald P. Bottaro
Donald P. Bottaro National Institutes of Health
Toru Miki
Toru Miki National Institutes of Health
Matthew T. Gillespie
Matthew T. Gillespie Monash University
Stephen J. Stahl
Stephen J. Stahl National Institutes of Health
Paul T. Wingfield
Paul T. Wingfield National Institutes of Health
Hideoki Ogawa
Hideoki Ogawa Juntendo University
Jeffrey A. Toretsky
Jeffrey A. Toretsky Georgetown University
Stuart Rudikoff
Stuart Rudikoff National Institutes of Health
Gerald R. Cunha
Gerald R. Cunha University of California, San Francisco

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