What is he best known for?
The fields of study he is best known for:
His main research concerns Molecular biology, Cell biology, Tyrosine kinase, Keratinocyte growth factor and Complementary DNA.
His Molecular biology study integrates concerns from other disciplines, such as Cell culture, Transfection, Growth factor receptor and Paracrine signalling.
His Cell biology research incorporates themes from Midbody and Cytokinesis.
His biological study spans a wide range of topics, including Epidermal growth factor, Growth factor receptor inhibitor, Epidermal growth factor receptor, TGF alpha and Gene family.
Toru Miki works mostly in the field of Expression cloning, limiting it down to topics relating to Rac GTP-Binding Proteins and, in certain cases, GTP-binding protein regulators, as a part of the same area of interest.
His Guanine nucleotide exchange factor research is multidisciplinary, relying on both Rho family of GTPases, RAC1 and MAPK/ERK pathway.
His most cited work include:
- A SINGLE ATAXIA TELANGIECTASIA GENE WITH A PRODUCT SIMILAR TO PI-3 KINASE (2378 citations)
- The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway (1508 citations)
- Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor (1021 citations)
What are the main themes of his work throughout his whole career to date?
Toru Miki mainly investigates Molecular biology, Cell biology, Gene, Complementary DNA and Genetics.
His Molecular biology research includes elements of Plasmid, cDNA library, Gene expression, Transfection and Homology.
His work deals with themes such as Fibroblast growth factor and Cytokinesis, which intersect with Cell biology.
His Fibroblast growth factor research includes themes of Heparan sulfate and Signal transduction.
His work in the fields of Oncogene, Nucleic acid sequence, Expression cloning and Promoter overlaps with other areas such as Expression vector.
Toru Miki interconnects Open reading frame, Peptide sequence, Gene isoform and Exon in the investigation of issues within Complementary DNA.
He most often published in these fields:
- Molecular biology (50.00%)
- Cell biology (36.27%)
- Gene (29.41%)
What were the highlights of his more recent work (between 2001-2007)?
- Cell biology (36.27%)
- Mitosis (10.78%)
- Cytokinesis (10.78%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cell biology, Mitosis, Cytokinesis, Guanine nucleotide exchange factor and RHOA.
Toru Miki has researched Cell biology in several fields, including Spindle apparatus, Epithelial polarity and Cell polarity.
The study incorporates disciplines such as Multipolar spindles, Anaphase, PLK1 and Spindle pole body in addition to Mitosis.
To a larger extent, Toru Miki studies GTPase with the aim of understanding Guanine nucleotide exchange factor.
Toru Miki combines subjects such as DNA repair and Septin with his study of GTPase.
His work carried out in the field of RHOA brings together such families of science as Nuclear localization sequence and Rho-associated protein kinase.
Between 2001 and 2007, his most popular works were:
- A spindle checkpoint arrest and a cytokinesis failure by the dominant-negative polo-box domain of Plk1 in U-2 OS cells (190 citations)
- Dissecting the Role of Rho-mediated Signaling in Contractile Ring Formation (171 citations)
- Phosphorylation of the cytokinesis regulator ECT2 at G2/M phase stimulates association of the mitotic kinase Plk1 and accumulation of GTP-bound RhoA. (98 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Cell biology, Cytokinesis, Mitosis, Guanine nucleotide exchange factor and RHOA.
Cell biology is represented through his Signal transduction and Rac GTP-Binding Proteins research.
His Signal transduction research is multidisciplinary, incorporating perspectives in Epithelial polarity and Protein kinase A.
He usually deals with Rac GTP-Binding Proteins and limits it to topics linked to Centralspindlin and Centralspindlin complex.
The concepts of his Cyclin-dependent kinase 1 study are interwoven with issues in PLK1, Kinase, Cell division and Phosphorylation.
His Subcellular localization research is multidisciplinary, incorporating elements of Malignant transformation, Cancer research, Nuclear localization sequence, NLS and Cell cycle.
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