Pier Paolo Di Fiore

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in Italy Leader Award
• 2022 - Research.com Biology and Biochemistry in Italy Leader Award
• 2010 - Member of Academia Europaea
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)
• Member of the European Molecular Biology Organization (EMBO)

Overview

Best Publications

• Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.

  Salvatore Pece;Daniela Tosoni;Stefano Confalonieri;Giovanni Mazzarol

  1114
  Citations

• Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

  Kaisa Haglund;Sara Sigismund;Simona Polo;Iwona Szymkiewicz

  1033
  Citations

• Clathrin-independent endocytosis of ubiquitinated cargos

  Sara Sigismund;Tanja Woelk;Claudia Puri;Elena Maspero

  1016
  Citations

• Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells

  Pier Paolo Di Fiore;Jacalyn H. Pierce;Timothy P. Fleming;Rachel Hazan

  855
  Citations

• The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells

  Angelo Cicalese;Giuseppina Bonizzi;Cristina E. Pasi;Mario Faretta

  832
  Citations

• A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

  Simona Polo;Sara Sigismund;Mario Faretta;Monica Guidi

  814
  Citations

• Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation.

  Sara Sigismund;Elisabetta Argenzio;Daniela Tosoni;Elena Cavallaro

  801
  Citations

• Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis

  Hong Chen;Silvia Fre;Vladimir I. Slepnev;Maria Rosaria Capua

  729
  Citations

• Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis.

  Salvatore Pece;Michela Serresi;Elisa Santolini;Maria Capra

  604
  Citations

• The endocytic matrix

  Giorgio Scita;Pier Paolo Di Fiore;Pier Paolo Di Fiore

  559
  Citations

• Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration.

  Andrea Palamidessi;Emanuela Frittoli;Massimiliano Garré;Mario Faretta

  538
  Citations

• Distinct monoubiquitin signals in receptor endocytosis

  Kaisa Haglund;Pier Paolo Di Fiore;Ivan Dikic

  522
  Citations

• All ErbB Receptors Other Than the Epidermal Growth Factor Receptor Are Endocytosis Impaired (

  Josep Baulida;Matthias H. Kraus;Maurizio Alimandi;Pier Paolo Di Fiore

  518
  Citations

• Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

  Enrica Migliaccio;Simonetta Mele;Anna E. Salcini;Giuliana Pelicci

  517
  Citations

• Abi1 is essential for the formation and activation of a WAVE2 signalling complex

  Metello Innocenti;Adriana Zucconi;Andrea Disanza;Emanuela Frittoli

  507
  Citations

• Alterations of the Notch pathway in lung cancer

  Britta Westhoff;Ivan N. Colaluca;Giovanni D'Ario;Maddalena Donzelli

  488
  Citations

• NUMB controls p53 tumour suppressor activity

  Ivan N. Colaluca;Daniela Tosoni;Paolo Nuciforo;Francesca Senic-Matuglia

  481
  Citations

• Numb Is an Endocytic Protein

  Elisa Santolini;Claudia Puri;Anna Elisabetta Salcini;Maria Cristina Gagliani

  466
  Citations

• Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase

  Achille Pellicioli;Chiara Lucca;Giordano Liberi;Federica Marini;Federica Marini

  457
  Citations

• Multiple monoubiquitination of RTKs is sufficient for their endocytosis and

  Kaisa Haglund;Sara Sigismund;Simona Polo;Iwona Szymkiewicz

  2
  Citations