2023 - Research.com Biology and Biochemistry in Italy Leader Award
2022 - Research.com Biology and Biochemistry in Italy Leader Award
2010 - Member of Academia Europaea
Member of the European Molecular Biology Organization (EMBO)
Pier Paolo Di Fiore mainly focuses on Cell biology, Signal transduction, Endocytosis, Endocytic cycle and Ubiquitin. His Cell biology study which covers Actin remodeling that intersects with Arp2/3 complex. His research integrates issues of Receptor, Epidermal growth factor, Kinase and Cell in his study of Signal transduction.
His Endocytosis study combines topics from a wide range of disciplines, such as Internalization, Cell signaling and Actin. His work carried out in the field of Endocytic cycle brings together such families of science as Endosome, Signalling and Cell fate determination. His Ubiquitin research includes themes of Protein structure and Plasma protein binding.
His scientific interests lie mostly in Cell biology, Endocytosis, Endocytic cycle, Cancer research and Signal transduction. His biological study focuses on Receptor tyrosine kinase. His work deals with themes such as Cell signaling and Signal transducing adaptor protein, which intersect with Endocytosis.
His Endocytic cycle research incorporates elements of Synaptic vesicle recycling, Endosome and Dynamin. His Cancer research research includes elements of Cancer, Cancer stem cell, Stem cell, NUMB and Immunology. His Signal transduction research incorporates themes from Receptor and Epidermal growth factor.
Pier Paolo Di Fiore focuses on Cancer research, Cell biology, Cancer, Breast cancer and Endocytic cycle. His Cancer research research integrates issues from Carcinogenesis, Cancer stem cell, Stem cell, Immunology and Metastasis. His studies in Cell biology integrate themes in fields like Internalization, Epidermal growth factor receptor and Cell polarity.
His Cancer research is multidisciplinary, incorporating elements of Regulation of gene expression, Lung cancer, Downregulation and upregulation and Computational biology. He interconnects Scaffold protein, In silico, Gene and Oncology in the investigation of issues within Breast cancer. His Endocytic cycle study deals with the bigger picture of Endocytosis.
His main research concerns Cell biology, Endocytic cycle, Cancer research, Endosome and Epidermal growth factor receptor. The concepts of his Cell biology study are interwoven with issues in Internalization, Bioinformatics and Clathrin. His research in Endocytic cycle intersects with topics in Cell adhesion and Cell polarity.
Pier Paolo Di Fiore has included themes like Immunology, Transactivation, Motility and Transforming growth factor, Transforming growth factor beta in his Cancer research study. He has researched Endosome in several fields, including Ubiquitin and GTPase. The various areas that Pier Paolo Di Fiore examines in his Signal transduction study include Mitosis and Cell membrane.
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Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content.
Salvatore Pece;Daniela Tosoni;Stefano Confalonieri;Giovanni Mazzarol.
Cell (2010)
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
Kaisa Haglund;Sara Sigismund;Simona Polo;Iwona Szymkiewicz.
Nature Cell Biology (2003)
Clathrin-independent endocytosis of ubiquitinated cargos
Sara Sigismund;Tanja Woelk;Claudia Puri;Elena Maspero.
Proceedings of the National Academy of Sciences of the United States of America (2005)
Overexpression of the human EGF receptor confers an EGF-dependent transformed phenotype to NIH 3T3 cells
Pier Paolo Di Fiore;Jacalyn H. Pierce;Timothy P. Fleming;Rachel Hazan.
Cell (1987)
The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells
Angelo Cicalese;Giuseppina Bonizzi;Cristina E. Pasi;Mario Faretta.
Cell (2009)
A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins
Simona Polo;Sara Sigismund;Mario Faretta;Monica Guidi.
Nature (2002)
Clathrin-mediated internalization is essential for sustained EGFR signaling but dispensable for degradation.
Sara Sigismund;Elisabetta Argenzio;Daniela Tosoni;Elena Cavallaro.
Developmental Cell (2008)
Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis
Hong Chen;Silvia Fre;Vladimir I. Slepnev;Maria Rosaria Capua.
Nature (1998)
Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis.
Salvatore Pece;Michela Serresi;Elisa Santolini;Maria Capra.
Journal of Cell Biology (2004)
The endocytic matrix
Giorgio Scita;Pier Paolo Di Fiore;Pier Paolo Di Fiore.
Nature (2010)
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