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Roman A. Zubarev

Roman A. Zubarev

D-Index & Metrics

Chemistry

D-Index
78
Citations
24453
World Ranking
3755
National Ranking
45

Biology and Biochemistry

D-Index
80
Citations
25944
World Ranking
4034
National Ranking
61

Overview

Roman A. Zubarev is affiliated with the Karolinska Institute in Sweden. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with a focus on molecular biology and spectroscopy. The work also covers immunology, radiology, nuclear medicine, imaging, and oncology as subfields. The main topics explored include advanced proteomics techniques and applications, mass spectrometry techniques and applications, monoclonal and polyclonal antibodies research, ubiquitin and proteasome pathways, protein purification and stability, chemical reactions and isotopes, and antimicrobial peptides and activities.

The scientist has a substantial publication record, contributing extensively to journals such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Analytical Chemistry, Journal of the American Society for Mass Spectrometry, and Methods in Molecular Biology.

Recent papers authored or coauthored by Roman A. Zubarev include:

  • Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin, 2020, Redox Biology
  • Conformational Selection in Biocatalytic Plastic Degradation by PETase, 2022, ACS Catalysis
  • System-wide identification and prioritization of enzyme substrates by thermal analysis, 2021, Nature Communications
  • Lysine-specific demethylase 1A restricts ex vivo propagation of human HSCs and is a target of UM171, 2020, Blood
  • DAF-16/FOXO requires Protein Phosphatase 4 to initiate transcription of stress resistance and longevity promoting genes, 2020, Nature Communications

The scientist frequently collaborates with a number of colleagues, including Ákos Végvári, Massimiliano Gaetani, Amir Ata Saei, Hassan Gharibi, and Zhaowei Meng. Their collaborative efforts reflect a broad interdisciplinary approach within their research network.

Best Publications

  • Electron Capture Dissociation of Multiply Charged Protein Cations. A Nonergodic Process

    Roman A. Zubarev;Neil L. Kelleher;Fred W. McLafferty

  • Electron Capture Dissociation for Structural Characterization of Multiply Charged Protein Cations

    Roman A. Zubarev;David M. Horn;Einar K. Fridriksson;Neil L. Kelleher

  • Orbitrap Mass Spectrometry

    Roman A. Zubarev;Alexander Makarov

  • Automated reduction and interpretation of high resolution electrospray mass spectra of large molecules.

    David M. Horn;Roman A. Zubarev;Fred W. McLafferty

  • Electron Capture Dissociation of Gaseous Multiply-Charged Proteins Is Favored at Disulfide Bonds and Other Sites of High Hydrogen Atom Affinity

    Roman A. Zubarev;Nathan A. Kruger;Einar K. Fridriksson;Mark A. Lewis

  • Reactions of polypeptide ions with electrons in the gas phase

    Roman A. Zubarev

  • Localization of labile posttranslational modifications by electron capture dissociation: The case of γ-carboxyglutamic acid

    Neil L. Kelleher;Roman A. Zubarev;Kristine Bush;Bruce Furie

  • Localization of O-glycosylation sites in peptides by electron capture dissociation in a Fourier transform mass spectrometer.

    Mirgorodskaya E;Roepstorff P;Zubarev Ra

  • Electron capture dissociation of singly and multiply phosphorylated peptides.

    Allan Stensballe;Ole Nørregaard Jensen;Jesper V. Olsen;Kim F. Haselmann

  • Electron-capture dissociation tandem mass spectrometry

    Roman A Zubarev

  • Automated de novo sequencing of proteins by tandem high-resolution mass spectrometry

    David M. Horn;Roman A. Zubarev;Fred W. McLafferty

  • Low-mass ions observed in plasma desorption mass spectrometry of high explosives

    Kristina Håkansson;Ramal V. Coorey;Ramal V. Coorey;Roman A. Zubarev;Victor L. Talrose

  • Towards an understanding of the mechanism of electron-capture dissociation: a historical perspective and modern ideas

    Roman A. Zubarev;Kim F. Haselmann;Bogdan Budnik;Frank Kjeldsen

  • Electron capture dissociation of gaseous multiply charged ions by Fourier-transform ion cyclotron resonance.

    Fred W. McLafferty;David M. Horn;Kathrin Breuker;Ying Ge

  • Electron detachment dissociation of peptide di-anions: an electron–hole recombination phenomenon

    Bogdan A. Budnik;Kim F. Haselmann;Roman A. Zubarev

  • The challenge of the proteome dynamic range and its implications for in‐depth proteomics

    Roman A. Zubarev

  • Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution

    Massimiliano Gaetani;Pierre Sabatier;Amir A Saei;Christian M Beusch

  • Release of Active Peptidyl Arginine Deiminases by Neutrophils Can Explain Production of Extracellular Citrullinated Autoantigens in Rheumatoid Arthritis Synovial Fluid

    Julia Spengler;Božo Lugonja;A. Jimmy Ytterberg;Roman A. Zubarev

  • De novo peptide sequencing and identification with precision mass spectrometry.

    Ari M. Frank;Mikhail M. Savitski;Michael N. Nielsen;Roman A. Zubarev

  • Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis.

    Anne Marie Quirke;Elena Birgitta Lugli;Natalia Wegner;Bart C. Hamilton

  • Dissociative capture of hot (3-13 eV) electrons by polypeptide polycations: an efficient process accompanied by secondary fragmentation

    Frank Kjeldsen;Kim F. Haselmann;Bogdan A. Budnik;Frank Jensen

  • Biomolecule Mass Spectrometry

    Fred W. McLafferty;Einar K. Fridriksson;David M. Horn;Mark A. Lewis

Frequent Co-Authors

Mikhail M. Savitski
Mikhail M. Savitski European Bioinformatics Institute
Michael L. Nielsen
Michael L. Nielsen University of Copenhagen
Fred W. McLafferty
Fred W. McLafferty Cornell University
Rikard Holmdahl
Rikard Holmdahl Karolinska Institute
Lars Klareskog
Lars Klareskog Karolinska Institute
Anca I. Catrina
Anca I. Catrina Karolinska University Hospital
Johan Frostegård
Johan Frostegård Karolinska Institute
Vivianne Malmström
Vivianne Malmström Karolinska University Hospital
Stig Linder
Stig Linder Linköping University
Jesper V. Olsen
Jesper V. Olsen University of Copenhagen

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