World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
110
Citations
44217
World Ranking
807
National Ranking
322

Biology and Biochemistry

D-Index
117
Citations
50221
World Ranking
719
National Ranking
456

Research.com Recognitions

  • 2003 - Fellow of Alfred P. Sloan Foundation

Overview

Neil L. Kelleher is affiliated with Northwestern University in the United States and has a research focus primarily in the fields of Biochemistry, Genetics and Molecular Biology, as well as Chemistry. Their work spans numerous subfields, particularly Molecular Biology, Spectroscopy, Pharmacology, Computational Mechanics, and Infectious Diseases.

The main topics covered in their research include Advanced Proteomics Techniques and Applications, Mass Spectrometry Techniques and Applications, Epigenetics and DNA Methylation, Metabolomics and Mass Spectrometry Studies, RNA modifications and cancer, Ion-surface interactions and analysis, and mechanisms related to RNA and protein synthesis.

Neil L. Kelleher has been involved in a broad array of scientific publications with a significant number of papers appearing in various venues. Frequent publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Proteome Research
  • Analytical Chemistry
  • Journal of the American Society for Mass Spectrometry
  • Nature Methods

Notable recent papers authored or co-authored by Kelleher include:

  • "The emerging landscape of single-molecule protein sequencing technologies," 2021, Nature Methods
  • "Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture," 2020, Nature
  • "The Human Proteoform Project: Defining the human proteome," 2021, Science Advances
  • "Multiplexed mass spectrometry of individual ions improves measurement of proteoforms and their complexes," 2020, Nature Methods
  • "An interpreted atlas of biosynthetic gene clusters from 1,000 fungal genomes," 2021, Proceedings of the National Academy of Sciences

Collaboration has played a significant role in Kelleher's scientific contributions. Frequent co-authors include Rafael D. Melani, Ryan T. Fellers, Jeannie M. Camarillo, Jared O. Kafader, and Paul M. Thomas.

Across their career, Kelleher has been recognized by receiving the Alfred P. Sloan Foundation fellowship in 2003.

Best Publications

  • Electron Capture Dissociation of Multiply Charged Protein Cations. A Nonergodic Process

    Roman A. Zubarev;Neil L. Kelleher;Fred W. McLafferty

  • Proteoform: a single term describing protein complexity

    Lloyd M Smith;Neil L Kelleher

  • Electron Capture Dissociation for Structural Characterization of Multiply Charged Protein Cations

    Roman A. Zubarev;David M. Horn;Einar K. Fridriksson;Neil L. Kelleher

  • How many human proteoforms are there

    Ruedi Aebersold;Jeffrey N. Agar;I. Jonathan Amster;Mark S. Baker

  • A computational framework to explore large-scale biosynthetic diversity

    Jorge C. Navarro-Muñoz;Nelly Selem-Mojica;Michael W. Mullowney;Satria A. Kautsar

  • EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation

    Wendy Béguelin;Relja Popovic;Matt Teater;Yanwen Jiang

  • Mapping intact protein isoforms in discovery mode using top-down proteomics

    John C. Tran;Leonid Zamdborg;Dorothy R. Ahlf;Dorothy R. Ahlf;Ji Eun Lee;Ji Eun Lee

  • Top down versus bottom up protein characterization by tandem high- resolution mass spectrometry

    Neil L. Kelleher;Hong Y. Lin;Gary A. Valaskovic;David J. Aaserud

  • Peer Reviewed: Top-Down Proteomics

    Neil L. Kelleher

  • Progress in Top-Down Proteomics and the Analysis of Proteoforms

    Timothy K. Toby;Luca Fornelli;Neil L. Kelleher

  • Top Down proteomics: Facts and perspectives

    Adam D. Catherman;Owen S. Skinner;Neil L. Kelleher

  • Decoding protein modifications using top-down mass spectrometry

    Nertila Siuti;Neil L Kelleher

  • A roadmap for natural product discovery based on large-scale genomics and metabolomics

    James R. Doroghazi;Jessica C. Albright;Anthony W. Goering;Kou San Ju

  • Precision proteomics: The case for high resolution and high mass accuracy

    Matthias Mann;Neil L. Kelleher

  • Genetically encoded short peptide tag for versatile protein labeling by Sfp phosphopantetheinyl transferase

    Jun Yin;Paul D. Straight;Shaun M. McLoughlin;Zhe Zhou

  • Attomole Protein Characterization by Capillary Electrophoresis-Mass Spectrometry

    Gary A. Valaskovic;Neil L. Kelleher;Fred W. McLafferty

  • A monovalent streptavidin with a single femtomolar biotin binding site

    Mark Howarth;Daniel J F Chinnapen;Kimberly Gerrow;Pieter C. Dorrestein

  • Localization of labile posttranslational modifications by electron capture dissociation: The case of γ-carboxyglutamic acid

    Neil L. Kelleher;Roman A. Zubarev;Kristine Bush;Bruce Furie

  • Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas

    Andrea Piunti;Rintaro Hashizume;Marc A. Morgan;Elizabeth T. Bartom

  • The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells

    Eva Martinez-Garcia;Relja Popovic;Dong Joon Min;Steve M.M. Sweet

Frequent Co-Authors

Paul M. Thomas
Paul M. Thomas Northwestern University
Christopher T. Walsh
Christopher T. Walsh Stanford University
Fred W. McLafferty
Fred W. McLafferty Cornell University
Jonathan D. Licht
Jonathan D. Licht University of Florida
Pieter C. Dorrestein
Pieter C. Dorrestein University of California, San Diego
William W. Metcalf
William W. Metcalf University of Illinois at Urbana-Champaign
Lloyd M. Smith
Lloyd M. Smith University of Wisconsin–Madison
Nancy P. Keller
Nancy P. Keller University of Wisconsin–Madison
Wilfred A. van der Donk
Wilfred A. van der Donk University of Illinois at Urbana-Champaign
Richard B. Silverman
Richard B. Silverman Northwestern University

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