World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
93
Citations
36147
World Ranking
671
National Ranking
368

Medicine

D-Index
93
Citations
36546
World Ranking
10782
National Ranking
5547

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Jonathan D. Licht is affiliated with the University of Florida in the United States. Their research spans multiple disciplines, primarily focusing on biochemistry, genetics, molecular biology, and medicine.

The main fields of study include Biochemistry, Genetics and Molecular Biology with 157 publications and Medicine with 104 publications. Within these fields, their work further specializes in subfields such as Molecular Biology, Hematology, Oncology, Cancer Research, and Immunology.

The research topics Jonathan D. Licht has focused on are diverse and include Protein Degradation and Inhibitors, Epigenetics and DNA Methylation, Multiple Myeloma Research and Treatments, Histone Deacetylase Inhibitors Research, Ubiquitin and proteasome pathways, Genomics and Chromatin Dynamics, and Acute Myeloid Leukemia Research.

Recent published papers by Licht and colleagues demonstrate the scope of their work:

  • Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture, 2020, Nature
  • Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition, 2021, Molecular Cell
  • Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins, 2021, Cell Reports
  • FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML, 2020, Nature Communications
  • Piperlongumine conjugates induce targeted protein degradation, 2023, Cell chemical biology

Licht collaborates frequently with several researchers, with notable frequent co-authors including Richard L. Bennett, Alberto Riva, Amin Sobh, Jianping Li, and Daphné Dupéré-Richer.

Their work is regularly published in venues such as Blood, Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), Cell Reports, and Nature Communications, reflecting both the volume and range of their research output.

Jonathan D. Licht has received recognition as a member of the Association of American Physicians.

Best Publications

  • Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.

    Maria E. Figueroa;Omar Abdel-Wahab;Chao Lu;Patrick S. Ward

  • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

    Thomas Thum;Carina Gross;Jan Fiedler;Thomas Fischer

  • Deconstructing a Disease: RAR, Its Fusion Partners, and Their Roles in the Pathogenesis of Acute Promyelocytic Leukemia

    Ari Melnick;Jonathan D. Licht

  • Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

    Laura A. Sena;Sha Li;Amit Jairaman;Murali Prakriya

  • Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

    Marco Tartaglia;Charlotte M Niemeyer;Alessandra Fragale;Alessandra Fragale;Xiaoling Song

  • Transcription factors, normal myeloid development, and leukemia.

    Daniel G. Tenen;Robert Hromas;Jonathan D. Licht;Dong-Er Zhang

  • EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation

    Wendy Béguelin;Relja Popovic;Matt Teater;Yanwen Jiang

  • Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the cdk-inhibitor p21waf1/cip1

    K Somasundaram;H Zhang;Y X Zeng;Y Houvras

  • Histone deacetylase inhibitors in cancer therapy: Is transcription the primary target?

    Ricky W Johnstone;Jonathan D Licht

  • Sprouty proteins: multifaceted negative-feedback regulators of receptor tyrosine kinase signaling

    Jacqueline M. Mason;Debra J. Morrison;M. Albert Basson;Jonathan D. Licht

  • Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17).

    Jonathan D. Licht;Christine Chomienne;Andre Goy;Alex Chen

  • The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells

    Eva Martinez-Garcia;Relja Popovic;Dong Joon Min;Steve M.M. Sweet

  • MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

    Maria E. Figueroa;Lucy Skrabanek;Yushan Li;Anchalee Jiemjit

  • Sprouty1 Is a Critical Regulator of GDNF/RET-Mediated Kidney Induction

    M. Albert Basson;M. Albert Basson;Simge Akbulut;Judy Watson-Johnson;Ruth Simon

  • Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.

    Jose M Polo;Tania Dell'Oso;Stella Maris Ranuncolo;Leandro Cerchietti

  • A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1.

    R W Johnstone;R H See;S F Sells;J Wang

  • Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.

    K.Farid Ahmad;K.Farid Ahmad;Ari Melnick;Stuart Lax;Denis Bouchard

  • Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation.

    Isabelle Gross;Bhramdeo Bassit;Miriam Benezra;Jonathan D. Licht

  • Sprouty1 Regulates Reversible Quiescence of a Self-Renewing Adult Muscle Stem Cell Pool during Regeneration

    Kelly L. Shea;Wanyi Xiang;Vincent S. LaPorta;Jonathan D. Licht

  • DNMT3A mutations in acute myeloid leukemia

    Mrinal Y Shah;Jonathan D Licht

Frequent Co-Authors

Ari Melnick
Ari Melnick Cornell University
Samuel Waxman
Samuel Waxman Icahn School of Medicine at Mount Sinai
Neil L. Kelleher
Neil L. Kelleher Northwestern University
Arthur Zelent
Arthur Zelent University of Miami
Ross L. Levine
Ross L. Levine Memorial Sloan Kettering Cancer Center
Constantine S. Mitsiades
Constantine S. Mitsiades Harvard University
James E. Bradner
James E. Bradner Amgen (United States)
Omar Abdel-Wahab
Omar Abdel-Wahab Memorial Sloan Kettering Cancer Center
Aviad Tsherniak
Aviad Tsherniak Broad Institute
Francisca Vazquez
Francisca Vazquez Broad Institute

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