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Medicine
Singapore
2026
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Biology and Biochemistry
Singapore
2023

D-Index & Metrics

Medicine

D-Index
132
Citations
59326
World Ranking
2329
National Ranking
8

Research.com Recognitions

  • 2026 - Research.com Medicine in Singapore Leader Award
  • 2025 - Research.com Medicine in Singapore Leader Award
  • 2023 - Research.com Biology and Biochemistry in Singapore Leader Award
  • 2022 - Research.com Biology and Biochemistry in Singapore Leader Award

Overview

Daniel G. Tenen is affiliated with the National University of Singapore in Singapore. Their research spans multiple fields primarily focused on biochemistry, genetics, and molecular biology, with significant contributions to medicine. The main areas of study include molecular biology, immunology, hematology, cancer research, and oncology.

The scientist's work concentrates on topics including RNA modifications and cancer, epigenetics and DNA methylation, renal and related cancers, cancer-related gene regulation, acute myeloid leukemia research, genomics and chromatin dynamics, and RNA research and splicing.

Frequent publication venues for Daniel G. Tenen include bioRxiv (Cold Spring Harbor Laboratory), Blood, Cancer Research, Nature Communications, and SSRN Electronic Journal.

Recent notable papers authored or co-authored by Daniel G. Tenen are:

  • Patients with Cancer Appear More Vulnerable to SARS-CoV-2: A Multicenter Study during the COVID-19 Outbreak, 2020, Cancer Discovery
  • EGFR signaling pathway as therapeutic target in human cancers, 2022, Seminars in Cancer Biology
  • APOE4 impairs the microglial response in Alzheimer's disease by inducing TGFβ-mediated checkpoints, 2023, Nature Immunology
  • NanoVar: accurate characterization of patients' genomic structural variants using low-depth nanopore sequencing, 2020, Genome biology
  • ZNF143 mediates CTCF-bound promoter-enhancer loops required for murine hematopoietic stem and progenitor cell function, 2021, Nature Communications

Daniel G. Tenen collaborates frequently with other researchers. Their frequent co-authors include Li Chai, Mahmoud A. Bassal, Henry Yang, Annalisa Di Ruscio, and Bon Q. Trinh.

Best Publications

  • EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib

    Susumu Kobayashi;Titus J. Boggon;Tajhal Dayaram;Pasi A. Jänne

  • Patients with Cancer Appear More Vulnerable to SARS-CoV-2: A Multicenter Study during the COVID-19 Outbreak.

    Mengyuan Dai;Dianbo Liu;Dianbo Liu;Miao Liu;Fuxiang Zhou

  • Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species.

    Rapolas Zilionis;Rapolas Zilionis;Camilla Engblom;Christina Pfirschke;Virginia Savova

  • Dominant-negative mutations of CEBPA , encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia

    Thomas Pabst;Beatrice U. Mueller;Pu Zhang;Hanna S. Radomska

  • Transcription factors, normal myeloid development, and leukemia.

    Daniel G. Tenen;Robert Hromas;Jonathan D. Licht;Dong-Er Zhang

  • Disruption of differentiation in human cancer: AML shows the way

    Daniel G Tenen

  • Transcription factors in myeloid development: balancing differentiation with transformation.

    Frank Rosenbauer;Daniel G. Tenen

  • Enhancement of Hematopoietic Stem Cell Repopulating Capacity and Self-Renewal in the Absence of the Transcription Factor C/EBPα

    Pu Zhang;Junko Iwasaki-Arai;Hiromi Iwasaki;Maris L. Fenyus

  • CCAAT/enhancer binding protein alpha is a regulatory switch sufficient for induction of granulocytic development from bipotential myeloid progenitors

    Hanna S. Radomska;Claudia S. Huettner;Pu Zhang;Tao Cheng

  • Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

    Frank Rosenbauer;Katharina Wagner;Jeffery L Kutok;Hiromi Iwasaki

  • AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

    Thomas Pabst;Beatrice U. Mueller;Nari Harakawa;Claudia Schoch

  • Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1.

    Pu Zhang;Gerhard Behre;Jing Pan;Atsushi Iwama

  • BIM Mediates EGFR Tyrosine Kinase Inhibitor-Induced Apoptosis in Lung Cancers with Oncogenic EGFR Mutations

    Daniel Botelho Costa;Balázs Halmos;Amit Kumar;Susan T Schumer

  • DNMT1-interacting RNAs block gene-specific DNA methylation

    Annalisa Di Ruscio;Alexander K. Ebralidze;Touati Benoukraf;Giovanni Amabile

  • Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.

    Hiromi Iwasaki;Chamorro Somoza;Hirokazu Shigematsu;Estelle A. Duprez

  • The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

    Hongbin Ji;Danan Li;Liang Chen;Takeshi Shimamura

  • The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor.

    Dong-Er Zhang;C. J. Hetherington;Hui-Min Chen;D. G. Tenen

  • Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

    Leilei Chen;Yan Li;Chi Ho Lin;Tim Hon Man Chan;Tim Hon Man Chan

  • Hematopoietic stem cell and multilineage defects generated by constitutive beta-catenin activation

    Marina Scheller;Joerg Huelsken;Frank Rosenbauer;Makoto Mark Taketo

  • Mutations of the transcription factor PU.1 are not associated with acute lymphoblastic leukaemia.

    B U Mueller;T Pabst;P Hauser;G Gilliland

Frequent Co-Authors

Koichi Akashi
Koichi Akashi Kyushu University
Henry Yang
Henry Yang National University of Singapore
Ruud Delwel
Ruud Delwel Erasmus MC
Hong Zhang
Hong Zhang Chinese Academy of Sciences
Constanze Bonifer
Constanze Bonifer University of Birmingham
Carsten Müller-Tidow
Carsten Müller-Tidow University Hospital Heidelberg
Steven J. Ackerman
Steven J. Ackerman University of Illinois at Chicago
Dietger Niederwieser
Dietger Niederwieser Leipzig University
Wolfgang Hiddemann
Wolfgang Hiddemann Ludwig-Maximilians-Universität München
Atsushi Iwama
Atsushi Iwama University of Tokyo

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