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Biology and Biochemistry

D-Index
78
Citations
22452
World Ranking
4532
National Ranking
2206

Overview

Dong-Er Zhang is affiliated with the University of California, San Diego in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine, with a significant focus on subfields including Molecular Biology, Immunology, Hematology, Oncology, and Cancer Research.

Their work explores multiple topics related to acute myeloid leukemia, RNA research and splicing, interferon and immune responses, as well as single-cell and spatial transcriptomics. Additional areas of research interest comprise immune cells in cancer, immunotherapy and immune responses, and RNA interference and gene delivery.

Notable recent publications by Dong-Er Zhang include:

  • Acute myeloid leukemia cell membrane-coated nanoparticles for cancer vaccination immunotherapy, 2021, Leukemia
  • Type I Interferon Regulates a Coordinated Gene Network to Enhance Cytotoxic T Cell-Mediated Tumor Killing, 2020, Cancer Discovery
  • Expansion of interferon inducible gene pool via USP18 inhibition promotes cancer cell pyroptosis, 2023, Nature Communications
  • Emerging role of immunogenic cell death in cancer immunotherapy, 2024, Frontiers in Immunology
  • Cell-cycle-gated feedback control mediates desensitization to interferon stimulation, 2020, eLife

Frequent publication venues for Zhang include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood Advances
  • Blood
  • Leukemia
  • Cell Reports

Zhang collaborates regularly with several co-authors, including Kei-ichiro Arimoto, Mengdan Liu, Amanda G Davis, Xiang-Dong Fu, and Ming Yan.

Best Publications

  • Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein α-deficient mice

    Dong-Er Zhang;Pu Zhang;Nai-dy Wang;Christopher J. Hetherington

  • Transcription factors, normal myeloid development, and leukemia.

    Daniel G. Tenen;Robert Hromas;Jonathan D. Licht;Dong-Er Zhang

  • UBP43 (USP18) Specifically Removes ISG15 from Conjugated Proteins

    Michael P. Malakhov;Oxana A. Malakhova;Keun Il Kim;Kenneth J. Ritchie

  • Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

    Zejuan Li;Jun Lu;Jun Lu;Miao Sun;Shuangli Mi

  • AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

    Youzhong Yuan;Liming Zhou;Toshihiro Miyamoto;Hiromi Iwasaki

  • Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene.

    Donald A. Yergeau;Christopher J. Hetherington;Qing Wang;Pu Zhang

  • CCAAT enhancer-binding protein (C/EBP) and AML1 (CBF alpha2) synergistically activate the macrophage colony-stimulating factor receptor promoter.

    Dong-Er Zhang;C. J. Hetherington;S. Meyers;K. L. Rhoades

  • UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity.

    Oxana A Malakhova;Keun I I Kim;Jiann-Kae Luo;Weiguo Zou

  • The 8;21 translocation in leukemogenesis

    Luke F. Peterson;Dong Er Zhang

  • Protein ISGylation modulates the JAK-STAT signaling pathway

    Oxana A. Malakhova;Ming Yan;Michael P. Malakhov;Youzhong Yuan

  • PU.1 (Spi-1) and C/EBP alpha regulate expression of the granulocyte-macrophage colony-stimulating factor receptor alpha gene.

    S. Hohaus;M. S. Petrovick;M. T. Voso;Zijie Sun

  • Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model

    Kristina L. Rhoades;Christopher J. Hetherington;Christopher J. Hetherington;Nari Harakawa;Nari Harakawa;Donald A. Yergeau;Donald A. Yergeau

  • A previously unidentified alternatively spliced isoform of t(8;21) transcript promotes leukemogenesis

    Ming Yan;Eiki Kanbe;Luke F Peterson;Anita Boyapati

  • R-ChIP Using Inactive RNase H Reveals Dynamic Coupling of R-loops with Transcriptional Pausing at Gene Promoters.

    Liang Chen;Jia-Yu Chen;Xuan Zhang;Ying Gu

  • Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection.

    Kenneth J Ritchie;Chang S Hahn;Keun Il Kim;Ming Yan

  • High-throughput Immunoblotting UBIQUITIN-LIKE PROTEIN ISG15 MODIFIES KEY REGULATORS OF SIGNAL TRANSDUCTION

    Michael P. Malakhov;Keun Il Kim;Oxana A. Malakhova;Barbara S. Jacobs

  • The Interferon-inducible Ubiquitin-protein Isopeptide Ligase (E3) EFP Also Functions as an ISG15 E3 Ligase

    Weiguo Zou;Dong-Er Zhang

  • Multiple Functional Domains of AML1: PU.1 and C/EBPα Synergize with Different Regions of AML1

    Martha S. Petrovick;Scott W. Hiebert;Alan D. Friedman;Christopher J. Hetherington

  • PU.1 (Spi-1) autoregulates its expression in myeloid cells.

    Hui-Min Chen;D. Ray-Gallet;Pu Zhang;C. J. Hetherington

  • Sp1 is a critical factor for the monocytic specific expression of human CD14.

    Dong-Er Zhang;C. J. Hetherington;Shencao Tan;S. E. Dziennis

Frequent Co-Authors

Xiang-Dong Fu
Xiang-Dong Fu Westlake University
Daniel G. Tenen
Daniel G. Tenen National University of Singapore
Peter Hokland
Peter Hokland Aarhus University
Karl S. Lang
Karl S. Lang University of Duisburg-Essen
Linheng Li
Linheng Li Stowers Institute for Medical Research
Koichi Akashi
Koichi Akashi Kyushu University
Philipp A. Lang
Philipp A. Lang Heinrich Heine University Düsseldorf
Gen-Sheng Feng
Gen-Sheng Feng University of California, San Diego
Edward D. Ball
Edward D. Ball University of California, San Diego
Cheryl L. Willman
Cheryl L. Willman University of New Mexico

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