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Medicine

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130
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72096
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2470
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Overview

Torsten Haferlach is affiliated with the MLL Munich Leukemia Laboratory in Germany. Their research primarily focuses on hematology, genetics, and molecular biology, with a significant emphasis on cancer research and immunology. The scientist's work contributes extensively to the understanding and treatment of various blood-related malignancies and disorders.

Haferlach's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these areas, they have specialized subfields such as:

  • Hematology
  • Genetics
  • Molecular Biology
  • Cancer Research
  • Immunology

The primary research topics addressed by Haferlach concern:

  • Acute Myeloid Leukemia Research
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Cancer Genomics and Diagnostics
  • Chronic Myeloid Leukemia Treatments
  • Chronic Lymphocytic Leukemia Research
  • Acute Lymphoblastic Leukemia Research
  • Digital Imaging for Blood Diseases

Their publications have been featured predominantly in the following venues:

  • Blood
  • Leukemia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • HemaSphere
  • Blood Advances

Torsten Haferlach has collaborated frequently with a number of co-authors including:

  • Manja Meggendorfer
  • Claudia Haferlach
  • Wolfgang Kern
  • Wencke Walter
  • Stephan Hütter

Notable recent publications by Haferlach include:

  • The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms, 2022, Leukemia
  • 2021 Update on MRD in acute myeloid leukemia: a consensus document from the European LeukemiaNet MRD Working Party, 2021, Blood
  • Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3-Internal Tandem Duplication Mutation (SORMAIN), 2020, Journal of Clinical Oncology
  • SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS, 2020, Blood
  • Mechanisms of antigen escape from BCMA- or GPRC5D-targeted immunotherapies in multiple myeloma, 2023, Nature Medicine

Best Publications

  • Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

    T Haferlach;Y Nagata;V Grossmann;Y Okuno

  • Analysis of FLT3 length mutations in 1003 patients with acute myeloid leukemia: correlation to cytogenetics, FAB subtype, and prognosis in the AMLCG study and usefulness as a marker for the detection of minimal residual disease.

    Susanne Schnittger;Claudia Schoch;Martin Dugas;Wolfgang Kern

  • BRAF mutations in hairy-cell leukemia

    Enrico Tiacci;Vladimir Trifonov;Gianluca Schiavoni;Antony Holmes

  • Minimal/measurable residual disease in AML: a consensus document from the European LeukemiaNet MRD Working Party.

    Gerrit J. Schuurhuis;Michael Heuser;Sylvie Freeman;Marie Christine Béne

  • Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype

    Susanne Schnittger;Claudia Schoch;Wolfgang Kern;Cristina Mecucci

  • Clinical Utility of Microarray-Based Gene Expression Profiling in the Diagnosis and Subclassification of Leukemia: Report From the International Microarray Innovations in Leukemia Study Group

    Torsten Haferlach;Alexander Kohlmann;Lothar Wieczorek;Giuseppe Basso

  • Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes.

    Peter Valent;Amy D. Klion;Hans-Peter Horny;Florence Roufosse

  • Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications.

    Guido Marcucci;Torsten Haferlach;Hartmut Döhner

  • Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: Consensus statements and report from a working conference

    Peter Valent;Hans-Peter Horny;John M. Bennett;Christa Fonatsch

  • Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

    Rongqing Pan;Leah J. Hogdal;Juliana M. Benito;Donna Bucci

  • Landscape Of Genetic Lesions In 944 Patients With Myelodysplastic Syndromes

    Yasunobu Nagata;Vera Grossmann;Yusuke Okuno;Ulrike Bacher

  • Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosmin

    Ramiro Garzon;Michela Garofalo;Maria Paola Martelli;Roger Briesewitz

  • Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor)

    Norbert Schmitz;Peter Dreger;Meinolf Suttorp;Ernst B. Rohwedder

  • AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

    Thomas Pabst;Beatrice U. Mueller;Nari Harakawa;Claudia Schoch

  • Prognostic Score Including Gene Mutations in Chronic Myelomonocytic Leukemia

    Raphaël Itzykson;Olivier Kosmider;Aline Renneville;Véronique Gelsi-Boyer

  • KIT-D816 mutations in AML1-ETO-positive AML are associated with impaired event-free and overall survival

    Susanne Schnittger;Tobias M. Kohl;Torsten Haferlach;Wolfgang Kern

  • Prognostic relevance of FLT3-TKD mutations in AML: the combination matters—an analysis of 3082 patients

    Ulrike Bacher;Claudia Haferlach;Wolfgang Kern;Torsten Haferlach

  • Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group.

    Thomas Büchner;Wolfgang Hiddemann;Bernhard Wörmann;Helmut Löffler

  • IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status

    Susanne Schnittger;Claudia Haferlach;Madlen Ulke;Tamara Alpermann

  • Frequent Pathway Mutations of Splicing Machinery in Myelodysplasia

    Kenichi Yoshida;Masashi Sanada;Yuichi Shiraishi;Daniel Nowak

Frequent Co-Authors

Wolfgang Kern
Wolfgang Kern Munich Leukemia Laboratory (Germany)
Claudia Haferlach
Claudia Haferlach Ludwig-Maximilians-Universität München
Susanne Schnittger
Susanne Schnittger Ludwig-Maximilians-Universität München
Claudia Schoch
Claudia Schoch MLL Munich Leukemia Laboratory
Wolfgang Hiddemann
Wolfgang Hiddemann Ludwig-Maximilians-Universität München
Martin Dugas
Martin Dugas Heidelberg University
Seishi Ogawa
Seishi Ogawa Kyoto University
Jaroslaw P. Maciejewski
Jaroslaw P. Maciejewski Cleveland Clinic
Nicholas C.P. Cross
Nicholas C.P. Cross University of Southampton
Mikkael A. Sekeres
Mikkael A. Sekeres Cleveland Clinic

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