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Medicine

D-Index
96
Citations
37679
World Ranking
9585
National Ranking
528

Overview

Claudia Haferlach is affiliated with Ludwig-Maximilians-Universität München in Germany and has contributed extensively to the field of medicine, with a focus on hematology. Their research encompasses a broad range of topics, with high activity in hematology, genetics, molecular biology, immunology, and oncology.

The scientist's work addresses several main topics in hematologic research:

  • Acute Myeloid Leukemia Research
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Multiple Myeloma Research and Treatments
  • Acute Lymphoblastic Leukemia Research
  • Chronic Myeloid Leukemia Treatments
  • Cancer Genomics and Diagnostics

Their frequent publication venues reflect the rheostat of their academic contributions, featuring prominent journals in their field:

  • Blood
  • Leukemia
  • HemaSphere
  • Blood Advances
  • Clinical Lymphoma Myeloma & Leukemia

Notable recent papers authored or co-authored by Claudia Haferlach include:

  • "Homozygous BCMA gene deletion in response to anti-BCMA CAR T cells in a patient with multiple myeloma" (2021) published in Nature Medicine
  • "Mechanisms of antigen escape from BCMA- or GPRC5D-targeted immunotherapies in multiple myeloma" (2023) published in Nature Medicine
  • "Molecular landscape and clonal architecture of adult myelodysplastic/myeloproliferative neoplasms" (2020) published in Blood
  • "Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia" (2021) published in Cancer Discovery
  • "Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL" (2020) published in Blood

Their frequent co-authors include several researchers with substantial collaborative ties, highlighting the extent and integration of their work within the hematology research community:

  • Torsten Haferlach
  • Manja Meggendorfer
  • Wolfgang Kern
  • Wencke Walter
  • Stephan Hütter

Claudia Haferlach's research spans various subfields within medicine, predominantly focusing on hematology (with 172 publications), genetics (105 publications), molecular biology (64 publications), immunology (37 publications), and oncology (28 publications), reflecting a multidisciplinary approach to blood cancers and disorders.

Best Publications

  • Frequent pathway mutations of splicing machinery in myelodysplasia

    Kenichi Yoshida;Masashi Sanada;Yuichi Shiraishi;Daniel Nowak

  • Landscape of genetic lesions in 944 patients with myelodysplastic syndromes

    T Haferlach;Y Nagata;V Grossmann;Y Okuno

  • BRAF mutations in hairy-cell leukemia

    Enrico Tiacci;Vladimir Trifonov;Gianluca Schiavoni;Antony Holmes

  • Deregulated expression of cytokine receptor gene, CRLF2 , is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia

    Lisa J. Russell;Melania Capasso;Inga Vater;Takashi Akasaka

  • Landscape Of Genetic Lesions In 944 Patients With Myelodysplastic Syndromes

    Yasunobu Nagata;Vera Grossmann;Yusuke Okuno;Ulrike Bacher

  • Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML).

    B. Hanfstein;M. C. Müller;R. Hehlmann;P. Erben

  • Prognostic relevance of FLT3-TKD mutations in AML: the combination matters—an analysis of 3082 patients

    Ulrike Bacher;Claudia Haferlach;Wolfgang Kern;Torsten Haferlach

  • Comprehensive genetic characterization of CLL: a study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV H status and immunophenotyping

    C Haferlach;F Dicker;S Schnittger;W Kern

  • Minimal residual disease levels assessed by NPM1 mutation–specific RQ-PCR provide important prognostic information in AML

    Susanne Schnittger;Wolfgang Kern;Claudia Tschulik;Tamara Weiss

  • Tolerability-Adapted Imatinib 800 mg/d Versus 400 mg/d Versus 400 mg/d Plus Interferon-α in Newly Diagnosed Chronic Myeloid Leukemia

    Rüdiger Hehlmann;Michael Lauseker;Susanne Jung-Munkwitz;Armin Leitner

  • Dynamics of clonal evolution in myelodysplastic syndromes

    Hideki Makishima;Hideki Makishima;Tetsuichi Yoshizato;Kenichi Yoshida;Mikkael Sekeres

  • Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms

    Ayana Kon;Lee Yung Shih;Masashi Minamino;Masashi Sanada;Masashi Sanada

  • Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1

    Alexander Kohlmann;Vera Grossmann;Hans-Ulrich Klein;Sonja Schindela

  • Myelodysplastic Cells in Patients Reprogram Mesenchymal Stromal Cells to Establish a Transplantable Stem Cell Niche Disease Unit

    Hind Medyouf;Maximilian Mossner;Johann Christoph Jann;Florian Nolte

  • Age-Related Risk Profile and Chemotherapy Dose Response in Acute Myeloid Leukemia: A Study by the German Acute Myeloid Leukemia Cooperative Group

    Thomas Büchner;Wolfgang E. Berdel;Claudia Haferlach;Torsten Haferlach

  • Deep Molecular Response Is Reached by the Majority of Patients Treated With Imatinib, Predicts Survival, and Is Achieved More Quickly by Optimized High-Dose Imatinib: Results From the Randomized CML-Study IV

    Rüdiger Hehlmann;Martin C. Müller;Michael Lauseker;Benjamin Hanfstein

  • Impact of additional cytogenetic aberrations at diagnosis on prognosis of CML: long-term observation of 1151 patients from the randomized CML Study IV

    Alice Fabarius;Armin Leitner;Andreas Hochhaus;Martin C. Müller

  • SF3B1 mutations correlated to cytogenetics and mutations in NOTCH1, FBXW7, MYD88, XPO1 and TP53 in 1160 untreated CLL patients

    S Jeromin;S Weissmann;C Haferlach;F Dicker

  • IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status

    Susanne Schnittger;Claudia Haferlach;Madlen Ulke;Tamara Alpermann

  • Frequent Pathway Mutations of Splicing Machinery in Myelodysplasia

    Kenichi Yoshida;Masashi Sanada;Yuichi Shiraishi;Daniel Nowak

Frequent Co-Authors

Wolfgang Kern
Wolfgang Kern Munich Leukemia Laboratory (Germany)
Torsten Haferlach
Torsten Haferlach MLL Munich Leukemia Laboratory
Susanne Schnittger
Susanne Schnittger Ludwig-Maximilians-Universität München
Andreas Hochhaus
Andreas Hochhaus Friedrich Schiller University Jena
Rüdiger Hehlmann
Rüdiger Hehlmann Heidelberg University
Seishi Ogawa
Seishi Ogawa Kyoto University
Nicholas C.P. Cross
Nicholas C.P. Cross University of Southampton
Andreas Reiter
Andreas Reiter Heidelberg University
Martin Dugas
Martin Dugas Heidelberg University
Stefan W. Krause
Stefan W. Krause University of Erlangen-Nuremberg

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