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Biology and Biochemistry

D-Index
105
Citations
53659
World Ranking
1177
National Ranking
698

Overview

George Thomas is affiliated with Oregon Health & Science University in the United States. Their research spans several areas within engineering and the life sciences, with a particular focus on the intersection of biomedical engineering and molecular biology.

Their recent publications include work on metabolic regulation and advanced bioengineering techniques. Notable papers are:

  • A compound directed against S6K1 hampers fat mass expansion and mitigates diet-induced hepatosteatosis (2022), published in JCI Insight
  • Engineering neuronal networks in granular microgels to innervate bioprinted cancer organoids on-a-chip (2025), published in Lab on a Chip

Thomas' research contributions are frequently published in venues such as:

  • Lab on a Chip
  • JCI Insight

The scientist collaborates regularly with several coauthors, including:

  • Jacob P. Fredrikson
  • Daniela M. Roth
  • Jason Cosgrove
  • Gülsu Şener
  • Lily A Crow

Their scholarly work primarily falls within the fields of engineering and biochemistry, genetics, and molecular biology. Subfields of focus include biomedical engineering and molecular biology, reflecting their interdisciplinary approach.

Key topics addressed in George Thomas's research are:

  • 3D Printing in Biomedical Research
  • Microfluidic and Bio-sensing Technologies
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • PI3K/AKT/mTOR signaling in cancer
  • Protein Kinase Regulation and GTPase Signaling
  • Metabolism, Diabetes, and Cancer

Best Publications

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

    Shunyou Wang;Jing Gao;Qunying Lei;Nora Rozengurt

  • Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

    W. Marston Linehan;Paul T. Spellman;Christopher J. Ricketts;Chad J. Creighton

  • Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR

    Mehran S. Neshat;Ingo K. Mellinghoff;Chris Tran;Bangyan Stiles

  • Rapamycin suppresses 5′TOP mRNA translation through inhibition of p70s6k

    Harold B.J. Jefferies;Stefano Fumagalli;Patrick B. Dennis;Christoph Reinhard

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen.

    S S Molloy;P A Bresnahan;S H Leppla;K R Klimpel

  • Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer

    Robert E. Reiter;Zhennen Gu;Tetsuro Watabe;George Thomas

  • Myc-driven murine prostate cancer shares molecular features with human prostate tumors.

    Katharine Ellwood-Yen;Thomas G. Graeber;John Wongvipat;M. Luisa Iruela-Arispe

  • Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase

    Takahiro Nobukuni;Manel Joaquin;Manel Joaquin;Marta Roccio;Stephen G. Dann

  • Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

    H. B. J. Jefferies;C. Reinhard;S. C. Kozma;G. Thomas

  • Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

    George V Thomas;Chris Tran;Ingo K Mellinghoff;Derek S Welsbie

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Prostate Pathology of Genetically Engineered Mice: Definitions and Classification. The Consensus Report from the Bar Harbor Meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee

    Scott B. Shappell;George V. Thomas;Richard L. Roberts;Ron Herbert

  • Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.

    Hiroshi Shima;Mario Pende;Yi Chen;Stefano Fumagalli

  • THE MODULAR PHOSPHORYLATION AND ACTIVATION OF P70S6K

    Nicholas Pullen;George Thomas

  • The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

    Christopher J Ricketts;Aguirre A De Cubas;Huihui Fan;Christof C Smith

  • First-in-Man Clinical Trial of the Oral Pan-AKT Inhibitor MK-2206 in Patients With Advanced Solid Tumors

    Timothy A. Yap;Li Yan;Amita Patnaik;Ivy Fearen

Frequent Co-Authors

Tomasz M. Beer
Tomasz M. Beer Oregon Health & Science University
Eric J. Small
Eric J. Small University of California, San Francisco
Martin E. Gleave
Martin E. Gleave University of British Columbia
Robert E. Reiter
Robert E. Reiter University of California, Los Angeles
Jiaoti Huang
Jiaoti Huang Duke University
Sara C. Kozma
Sara C. Kozma University of Cincinnati
Kim N. Chi
Kim N. Chi BC Cancer Agency
Primo N. Lara
Primo N. Lara University of California, Davis
Joshua M. Stuart
Joshua M. Stuart University of California, Santa Cruz

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