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Kazuei Igarashi

Kazuei Igarashi

D-Index & Metrics

Biology and Biochemistry

D-Index
86
Citations
27050
World Ranking
2958
National Ranking
186

Overview

Kazuei Igarashi is affiliated with Chiba University in Japan and has contributed extensively to research in biochemistry, genetics, and molecular biology. With a primary focus on molecular biology and biochemistry, their work also spans pharmacology, cell biology, and psychiatry and mental health.

The main topics explored in their research include:

  • Polyamine Metabolism and Applications
  • Amino Acid Enzymes and Metabolism
  • Epigenetics and DNA Methylation
  • Cannabis and Cannabinoid Research
  • Biochemical Analysis and Sensing Techniques
  • Schizophrenia research and treatment
  • Aldose Reductase and Taurine

The most frequent publication venues for their work are:

  • International Journal of Molecular Sciences
  • Journal of Biological Chemistry
  • Research Square (Research Square)
  • Medical Sciences
  • Amino Acids

Among recent papers authored by or involving Kazuei Igarashi are:

  • "Polyamines regulate gene expression by stimulating translation of histone acetyltransferase mRNAs," 2020, Journal of Biological Chemistry
  • "Polyamine-Rich Diet Elevates Blood Spermine Levels and Inhibits Pro-Inflammatory Status: An Interventional Study," 2021, Medical Sciences
  • "Ischemic stroke disrupts the endothelial glycocalyx through activation of proHPSE via acrolein exposure," 2020, Journal of Biological Chemistry
  • "Cytotoxic Mechanism of Excess Polyamines Functions through Translational Repression of Specific Proteins Encoded by Polyamine Modulon," 2020, International Journal of Molecular Sciences
  • "Functional roles of polyamines and their metabolite acrolein in eukaryotic cells," 2021, Amino Acids

Kazuei Igarashi has collaborated frequently with several researchers, including:

  • Takeshi Uemura
  • Keiko Kashiwagi
  • Akihiko Sakamoto
  • Yusuke Terui
  • Toshihiko Toida

Their research output includes 46 publications in the broader fields of biochemistry, genetics, and molecular biology, complemented by 23 publications related to medicine. The scientist's work engages molecular mechanisms underlying polyamine metabolism and its applications, with detailed study of amino acid enzymes, epigenetic regulation, and biochemical pathways associated with health and disease.

Best Publications

  • Polyamines: Mysterious Modulators of Cellular Functions

    Kazuei Igarashi;Keiko Kashiwagi

  • Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins.

    Yaeta Endo;Kunio Tsurugi;Takashi Yutsudo;Yoshifumi Takeda

  • Modulation of cellular function by polyamines

    Kazuei Igarashi;Keiko Kashiwagi

  • Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination.

    Yasuko Murakami;Senya Matsufuji;Takaaki Kameji;Shin-Ichi Hayashi

  • Electron microscopic studies on experimental poisoning in mice induced by cylindrospermopsin isolated from blue-green alga Umezakia natans.

    K. Terao;S. Ohmori;K. Igarashi;I. Ohtani

  • Estimation of polyamine binding to macromolecules and ATP in bovine lymphocytes and rat liver.

    S.-I. Watanabe;K. Kusama-Eguchi;H. Kobayashi;K. Igarashi

  • Expression and properties of two types of protein kinase C: alternative splicing from a single gene.

    Yoshitaka Ono;Ushio Kikkawa;Kouji Ogita;Tomoko Fujii

  • Excess of De Novo Deleterious Mutations in Genes Associated with Glutamatergic Systems in Nonsyndromic Intellectual Disability

    Fadi F. Hamdan;Julie Gauthier;Yoichi Araki;Da-Ting Lin

  • Polyamine transport in bacteria and yeast.

    Kazuei Igarashi;Keiko Kashiwagi

  • Decrease in polyamines with aging and their ingestion from food and drink.

    Kazuhiro Nishimura;Ritsuko Shiina;Keiko Kashiwagi;Kazuei Igarashi

  • Excretion and uptake of cadaverine by CadB and its physiological functions in Escherichia coli.

    Waraporn Soksawatmaekhin;Aiko Kuraishi;Kaori Sakata;Keiko Kashiwagi

  • Channel blockers acting at N-methyl-D-aspartate receptors: differential effects of mutations in the vestibule and ion channel pore.

    Keiko Kashiwagi;Takashi Masuko;Christopher D. Nguyen;Tomoko Kuno

  • Malignant transformation by overproduction of translation initiation factor eIF4G.

    Tomomi Fukuchi-Shimogori;Itsuko Ishii;Keiko Kashiwagi;Hiroko Mashiba

  • Inhibition by polyamines of lipid peroxide formation in rat liver microsomes

    Mitsukazu Kitada;Kazuei Igarashi;Seiyu Hirose;Haruo Kitagawa

  • Polyamine Oxidase and Acrolein as Novel Biochemical Markers for Diagnosis of Cerebral Stroke

    Hideyuki Tomitori;Teruyoshi Usui;Naokatsu Saeki;Shiro Ueda

  • Polyamine cytotoxicity in the presence of bovine serum amine oxidase.

    Shahana Sharmin;Kaori Sakata;Keiko Kashiwagi;Shiro Ueda

  • Characteristics of cellular polyamine transport in prokaryotes and eukaryotes.

    Kazuei Igarashi;Keiko Kashiwagi

  • A regulatory domain (R1-R2) in the amino terminus of the N-methyl-D-aspartate receptor: effects of spermine, protons, and ifenprodil, and structural similarity to bacterial leucine/isoleucine/valine binding protein.

    Takashi Masuko;Keiko Kashiwagi;Tomoko Kuno;Nguyen D. Nguyen

  • Polyamine Modulon in Escherichia coli: Genes Involved in the Stimulation of Cell Growth by Polyamines

    Kazuei Igarashi;Keiko Kashiwagi

  • Formation of a compensatory polyamine by Escherichia coli polyamine-requiring mutants during growth in the absence of polyamines.

    K Igarashi;K Kashiwagi;H Hamasaki;A Miura

Frequent Co-Authors

Keiko Kashiwagi
Keiko Kashiwagi Chiba Institute of Science
Toshihiko Toida
Toshihiko Toida Chiba University
Akira Ishihama
Akira Ishihama Hosei University
Akira Kaji
Akira Kaji University of Pennsylvania
Yoshifumi Takeda
Yoshifumi Takeda Okayama University
Tsuyoshi Inoue
Tsuyoshi Inoue Osaka University
Masaru Miyazaki
Masaru Miyazaki International University of Health and Welfare
Hiromitsu Takayama
Hiromitsu Takayama Chiba University
Kosuke Morikawa
Kosuke Morikawa Kyoto University

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