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Stephen F. Traynelis

Stephen F. Traynelis

D-Index & Metrics

Biology and Biochemistry

D-Index
91
Citations
36061
World Ranking
2293
National Ranking
1227

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Stephen F. Traynelis is affiliated with Emory University in the United States and focuses primarily on research within biochemistry, genetics, and molecular biology, as well as neuroscience. Their work spans molecular biology, cellular and molecular neuroscience, genetics, psychiatry and mental health, and neurology.

Their research encompasses several prominent topics, including:

  • Neuroscience and Neuropharmacology Research
  • Genetics and Neurodevelopmental Disorders
  • Ion channel regulation and function
  • Receptor Mechanisms and Signaling
  • RNA and protein synthesis mechanisms
  • Genomics and Rare Diseases
  • Epilepsy research and treatment

Major recent publications by Traynelis include:

  • Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels, 2021, Pharmacological Reviews
  • Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry, 2023, Neuropsychopharmacology
  • Modelling and treating GRIN2A developmental and epileptic encephalopathy in mice, 2020, Brain
  • Clinical and therapeutic significance of genetic variation in the GRIN gene family encoding NMDARs, 2021, Neuropharmacology
  • Biased modulators of NMDA receptors control channel opening and ion selectivity, 2020, Nature Chemical Biology

Traynelis frequently publishes in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain
  • Neuropharmacology
  • Journal of Pharmacology and Experimental Therapeutics
  • Cellular and Molecular Life Sciences

The scientist has collaborated extensively with several researchers including:

  • Hongjie Yuan
  • Riley E. Perszyk
  • Scott J. Myers
  • Dennis C. Liotta
  • Chad R. Camp

Stephen F. Traynelis was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2014.

Best Publications

  • THE GLUTAMATE RECEPTOR ION CHANNELS

    Raymond Dingledine;Karin Borges;Derek Bowie;Stephen F. Traynelis

  • Glutamate Receptor Ion Channels: Structure, Regulation, and Function

    Stephen Traynelis;Lonnie P. Wollmuth;Chris J. McBain;Frank S. Menniti

  • Control of GluR1 AMPA Receptor Function by cAMP-Dependent Protein Kinase

    T. G. Banke;D. Bowie;H.-K. Lee;R. L. Huganir

  • Proton inhibition of N-methyl-D-aspartate receptors in cerebellar neurons.

    Stephen F. Traynelis;Stuart G. Cull-Candy

  • Potassium-induced spontaneous electrographic seizures in the rat hippocampal slice

    S. F. Traynelis;R. Dingledine

  • Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.

    Kasper B. Hansen;Lonnie P. Wollmuth;Derek Bowie;Hiro Furukawa

  • Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines

    Stephen F. Traynelis;Melissa Hartley;Stephen F. Heinemann

  • Metabotropic Glutamate Receptors 1 and 5 Differentially Regulate CA1 Pyramidal Cell Function

    G Mannaioni;M J Marino;O Valenti;O Valenti;S F Traynelis

  • Potentiation of NMDA receptor currents by arachidonic acid

    Barbara Miller;Monique Sarantis;Stephen F. Traynelis;David Attwell

  • Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles

    Kevin Erreger;Shashank M. Dravid;Tue G. Banke;David J. A. Wyllie

  • Structure, function, and allosteric modulation of NMDA receptors.

    Kasper B. Hansen;Feng Yi;Riley E. Perszyk;Hiro Furukawa

  • Structural basis for partial agonist action at ionotropic glutamate receptors

    Rongsheng Jin;Tue G Banke;Mark L Mayer;Stephen F Traynelis

  • Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ

    R A Silver;S F Traynelis;S G Cull-Candy

  • Adenosine A2A receptor mediates microglial process retraction

    Anna G Orr;Adam L Orr;Xiao-Jiang Li;Robert E Gross

  • Serine proteases and brain damage - is there a link?

    Melissa B. Gingrich;Stephen F. Traynelis

  • Control of Voltage-Independent Zinc Inhibition of NMDA Receptors by the NR1 Subunit

    Stephen F. Traynelis;Michele F. Burgess;Fang Zheng;Polina Lyuboslavsky

  • Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor

    Jane M. Sullivan;Stephen F. Traynelis;Stephen F. Traynelis;Huei Sheng Vincent Chen;Walter Escobar

  • Potentiation of NMDA receptor function by the serine protease thrombin.

    Melissa B. Gingrich;Candice E. Junge;Polina Lyuboslavsky;Stephen F. Traynelis

  • Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating

    Anders S. Kristensen;Meagan A. Jenkins;Tue G. Banke;Arne Schousboe

  • Regional Variation of Extracellular Space in the Hippocampus

    Chris J. McBain;Stephen F. Traynelis;Raymond Dingledine

Frequent Co-Authors

Hongjie Yuan
Hongjie Yuan Emory University
Dennis C. Liotta
Dennis C. Liotta Emory University
Raymond Dingledine
Raymond Dingledine Emory University
James P. Snyder
James P. Snyder Emory University
C. Justin Lee
C. Justin Lee Institute for Basic Science
Yoland Smith
Yoland Smith Emory University
David J. A. Wyllie
David J. A. Wyllie University of Edinburgh
Chris J. McBain
Chris J. McBain National Institutes of Health
John R. Hepler
John R. Hepler Emory University
Stuart G. Cull-Candy
Stuart G. Cull-Candy University College London

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