World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
77
Citations
34527
World Ranking
4679
National Ranking
2266

Overview

Mark L. Mayer is affiliated with the National Institutes of Health in the United States. Their research focuses primarily on neuroscience, biochemistry, genetics, molecular biology, and medicine, with a particular emphasis on cellular and molecular neuroscience, molecular biology, neurology, infectious diseases, and epidemiology.

The main topics explored in Mayer's work include neuroscience and neuropharmacology research, ion channel regulation and function, photoreceptor and optogenetics research, long-term effects of COVID-19, COVID-19 clinical research studies, receptor mechanisms and signaling, and biochemical analysis and sensing techniques.

Mayer has published extensively, contributing to a variety of scientific journals. Frequent publication venues include the Journal of Hypertension, IUPHAR/BPS Guide to Pharmacology CITE, Neuropharmacology, The Journal of Physiology, and Methods in Molecular Biology. The number of publications across these venues indicates sustained research activity in these fields.

Their notable recent papers are:

  • Structural biology of kainate receptors, 2021, Neuropharmacology
  • Glutamate receptors from diverse animal species exhibit unexpected structural and functional diversity, 2020, The Journal of Physiology
  • Ionotropic glutamate receptors in GtoPdb v.2023.1, 2023, IUPHAR/BPS Guide to Pharmacology CITE
  • Expression and Functional Analysis of Ctenophore Glutamate Receptor Genes, 2024, Methods in Molecular Biology
  • Partial agonists go molecular, 2021, Trends in Pharmacological Sciences

Mayer has collaborated frequently with a group of coauthors who have appeared in multiple publications together. These include Jeffrey C. Watkins, Faiz Talibov, Bernhard Bettler, Graham L. Collingridge, and Raymond Dingledine. Such collaborations reflect interdisciplinary and collective research efforts in related scientific domains.

Best Publications

  • NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones

    Amy B. MacDermott;Amy B. MacDermott;Mark L. Mayer;Gary L. Westbrook;Stephen J. Smith

  • Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones.

    M. L. Mayer;Gary Westbrook

  • Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons.

    Gary L. Westbrook;Mark L. Mayer

  • Mechanism of glutamate receptor desensitization

    Yu Sun;Rich Olson;Michelle Horning;Neali Armstrong

  • Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

    DK Patneau;ML Mayer

  • Inward Rectification of Both AMPA and Kainate Subtype Glutamate Receptors Generated by Polyamine-Mediated Ion Channel Block

    Derek Bowie;Mark L. Mayer

  • Selective modulation of desensitization at AMPA versus kainate receptors by cyclothiazide and concanavalin A

    K.M. Partin;D.K. Patneau;C.A. Winters;M.L. Mayer

  • Excitatory amino acid receptors, second messengers and regulation of intracellular Ca2+ in mammalian neurons

    Mark L. Mayer;Richard J. Miller

  • Structure and function of glutamate receptor ion channels.

    Mark L. Mayer;Neali Armstrong

  • Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine

    Mark L. Mayer;Ladislav Vyklicky;John Clements

  • A voltage-clamp analysis of inward (anomalous) rectification in mouse spinal sensory ganglion neurones.

    M. L. Mayer;Gary Westbrook

  • Structural basis for partial agonist action at ionotropic glutamate receptors

    Rongsheng Jin;Tue G Banke;Mark L Mayer;Stephen F Traynelis

  • Glutamate receptor ion channels.

    Mark L Mayer

  • Glial cells of the oligodendrocyte lineage express both kainate- and AMPA-preferring subtypes of glutamate receptor

    Doris K. Patneau;Paul W. Wright;Christine Winters;Mark L. Mayer

  • Hippocampal neurons exhibit cyclothiazide-sensitive rapidly desensitizing responses to kainate

    Doris K. Patneau;Ladislav Vyklicky;Mark L. Mayer

  • Functional characterization of a potassium-selective prokaryotic glutamate receptor

    Guo-Qiang Chen;Changhai Cui;Mark L. Mayer;Eric Gouaux

  • AMPA Receptor Flip/Flop Mutants Affecting Deactivation, Desensitization, and Modulation by Cyclothiazide, Aniracetam, and Thiocyanate

    Kathryn M. Partin;Mark W. Fleck;Mark L. Mayer

  • Glutamate receptors at atomic resolution

    Mark L. Mayer

  • Modulation of excitatory amino acid receptors by group IIB metal cations in cultured mouse hippocampal neurones.

    M L Mayer;L Vyklicky;G L Westbrook

  • Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity.

    Mark L. Mayer

Frequent Co-Authors

Peter Schuck
Peter Schuck National Institutes of Health
Eric Gouaux
Eric Gouaux Oregon Health & Science University
Ladislav Vyklicky
Ladislav Vyklicky Czech Academy of Sciences
Gary L. Westbrook
Gary L. Westbrook Oregon Health & Science University
Sriram Subramaniam
Sriram Subramaniam University of British Columbia
David E. Jane
David E. Jane University of Bristol
Christophe Mulle
Christophe Mulle University of Bordeaux
Patrick O. Brown
Patrick O. Brown Stanford University
Christian Rosenmund
Christian Rosenmund Charité - University Medicine Berlin
Evelyne Sernagor
Evelyne Sernagor Newcastle University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Mark L. Mayer

Trending Scientists

Recently Published Articles