David E. Jane

Best Publications

• Pharmacological agents acting at subtypes of metabotropic glutamate receptors

  Darryle D. Schoepp;David E. Jane;James A. Monn

  1261
  Citations

• Induction of LTP in the hippocampus needs synaptic activation of glutamate metabotropic receptors

  Zafar I. Bashir;Zuner A. Bortolotto;Ceri H. Davies;Nicola Berretta

  890
  Citations

• (RS)-2-Chloro-5-Hydroxyphenylglycine (CHPG) Activates mGlu5, but not mGlu1, Receptors Expressed in CHO Cells and Potentiates NMDA Responses in the Hippocampus

  Andrew J Doherty;MJ Palmer;Jeremy M Henley;Graham L Collingridge

  435
  Citations

• The glutamate story

  Jeffrey C Watkins;David E Jane

  415
  Citations

• The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus

  M.J. Palmer;A.J. Irving;G.R. Seabrook;D.E. Jane

  397
  Citations

• Kainate receptors: pharmacology, function and therapeutic potential.

  David E Jane;David Lodge;Graham L Collingridge

  327
  Citations

• The NMDA receptor as a target for cognitive enhancement.

  Graham L. Collingridge;Arturas Volianskis;Neil Bannister

  293
  Citations

• Long-term potentiation and the role of N-methyl-D-aspartate receptors.

  Arturas Volianskis;Morten S. Jensen;Zuner A. Bortolotto

  274
  Citations

• Competitive antagonism at metabotropic glutamate receptors by (S) -4-carboxyphenylglycine and (RS) -α-methyl-4-carboxyphenylglycine

  Sean A. Eaton;David E. Jane;Philip L.St.J. Jones;Richard H.P. Porter

  267
  Citations

• Actions of two new antagonists showing selectivity for different sub-types of metabotropic glutamate receptor in the neonatal rat spinal cord

  D. E. Jane;P. L. S. J. Jones;P. C. K. Pook;H. W. Tse

  214
  Citations

• Distinct NMDA Receptor Subpopulations Contribute to Long-Term Potentiation and Long-Term Depression Induction

  Sabina Hrabetova;Peter Serrano;Nancy Blace;Heong W. Tse

  203
  Citations

• Metabotropic glutamate receptors contribute to the induction of long-term depression in the CA1 region of the hippocampus.

  Zafar I. Bashir;David E. Jane;David C. Sunter;Jeffery C. Watkins

  195
  Citations

• Structure–activity analysis of a novel NR2C/NR2D-preferring NMDA receptor antagonist: 1-(phenanthrene-2-carbonyl) piperazine-2,3-dicarboxylic acid

  Bihua Feng;Heong W Tse;Donald A Skifter;Richard Morley

  176
  Citations

• Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system

  E. F. Birse;S. A. Eaton;D. E. Jane;P. L. Saint J. Jones

  173
  Citations

• (S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord.

  Nicola K Thomas;Rebecca A Wright;Patrick A Howson;Ann E Kingston

  168
  Citations

• Extrasynaptic NR2D-containing NMDARs are recruited to the synapse during LTP of NMDAR-EPSCs

  Sarah C. Harney;David E. Jane;Roger Anwyl

  156
  Citations

• NMDA receptor-dependent long-term potentiation comprises a family of temporally overlapping forms of synaptic plasticity that are induced by different patterns of stimulation.

  Pojeong Park;Arturas Volianskis;Thomas M. Sanderson;Zuner A. Bortolotto

  153
  Citations

• Potent antagonists at the L-AP4- and (1S,3S)-ACPD-sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord

  D E Jane;N K Thomas;H W Tse;J C Watkins

  151
  Citations

• New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord

  D.E. Jane;K. Pittaway;D.C. Sunter;N.K. Thomas

  148
  Citations

• Crystal Structures of the Kainate Receptor GluR5 Ligand Binding Core Dimer with Novel GluR5-Selective Antagonists

  Mark L. Mayer;Alokesh Ghosal;Nigel P. Dolman;David E. Jane

  142
  Citations