Michael J. Rowan

Research.com Recognitions

• 2026 - Research.com Neuroscience in Ireland Leader Award
• 2025 - Research.com Neuroscience in Ireland Leader Award
• 2023 - Research.com Neuroscience in Ireland Leader Award
• 2022 - Research.com Neuroscience in Ireland Leader Award

Overview

Best Publications

• Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo.

  Dominic M. Walsh;Igor Klyubin;Julia V. Fadeeva;William K. Cullen

  5554
  Citations

• Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory.

  Ganesh M Shankar;Shaomin Li;Tapan H Mehta;Amaya Garcia-Munoz

  4513
  Citations

• Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty

  Shaomin Li;William K. Cullen;Roger Anwyl;Michael J. Rowan

  789
  Citations

• Amyloid-β oligomers: their production, toxicity and therapeutic inhibition

  D. M. Walsh;I. Klyubin;J. V. Fadeeva;M. J. Rowan

  768
  Citations

• Block of Long-Term Potentiation by Naturally Secreted and Synthetic Amyloid β-Peptide in Hippocampal Slices Is Mediated via Activation of the Kinases c-Jun N-Terminal Kinase, Cyclin-Dependent Kinase 5, and p38 Mitogen-Activated Protein Kinase as well as Metabotropic Glutamate Receptor Type 5

  Qinwen Wang;Dominic M. Walsh;Michael J. Rowan;Dennis J. Selkoe

  677
  Citations

• Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo

  Igor Klyubin;Dominic M Walsh;Dominic M Walsh;Cynthia A Lemere;William K Cullen

  676
  Citations

• Behavioural stress facilitates the induction of long-term depression in the hippocampus

  Lin Xu;Roger Anwyl;Michael J. Rowan

  604
  Citations

• Stimulation on the Positive Phase of Hippocampal Theta Rhythm Induces Long-Term Potentiation That Can Be Depotentiated by Stimulation on the Negative Phase in Area CA1 In Vivo

  Christian Hölscher;Roger Anwyl;Michael J. Rowan

  578
  Citations

• Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization.

  Igor Klyubin;Vicki Betts;Alfred T. Welzel;Kaj Blennow

  392
  Citations

• Interaction between prion protein and toxic amyloid β assemblies can be therapeutically targeted at multiple sites

  Darragh B. Freir;Andrew J. Nicoll;Igor Klyubin;Silvia Panico

  341
  Citations

• Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments.

  William K. Cullen;Yoo-Hun Suh;Roger Anwyl;Michael J. Rowan

  338
  Citations

• Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus

  Lin Xu;Roger Anwyl;Michael J. Rowan

  326
  Citations

• The role of cell-derived oligomers of Aβ in Alzheimer's disease and avenues for therapeutic intervention

  D.M. Walsh;D.M. Walsh;I. Klyubin;G.M. Shankar;M. Townsend

  312
  Citations

• Glucocorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress

  Lin Xu;Christian Holscher;Roger Anwyl;Michael J. Rowan

  296
  Citations

• Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

  Linda A. Kotilinek;Marcus A. Westerman;Qinwen Wang;Qinwen Wang;Kimberly Panizzon

  292
  Citations

• β-Amyloid-Mediated Inhibition of NMDA Receptor-Dependent Long-Term Potentiation Induction Involves Activation of Microglia and Stimulation of Inducible Nitric Oxide Synthase and Superoxide

  Qinwen Wang;Michael J. Rowan;Roger Anwyl

  285
  Citations

• Synaptic plasticity in animal models of early Alzheimer's disease

  Michael J Rowan;Igor Klyubin;William K Cullen;Roger Anwyl

  280
  Citations

• Alzheimer's disease brain-derived amyloid-β-mediated inhibition of LTP in vivo is prevented by immunotargeting cellular prion protein.

  Andrew E Barry;Igor Klyubin;Jessica M Mc Donald;Alexandra J Mably

  278
  Citations

• What electrophysiology tells us about Alzheimer's disease: a window into the synchronization and connectivity of brain neurons.

  Claudio Babiloni;Katarzyna Blinowska;Laura Bonanni;Andrej Cichocki

  262
  Citations

• Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: rapid actions of serotonergic and antidepressant agents.

  Alison C. Shakesby;Roger Anwyl;Michael J. Rowan

  245
  Citations

• Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo.

  Joung-Hun Kim;Roger Anwyl;Yoo-Hun Suh;Mustafa B. A. Djamgoz

  242
  Citations