Roger Anwyl

Research.com Recognitions

• 2023 - Research.com Neuroscience in Ireland Leader Award
• 2022 - Research.com Neuroscience in Ireland Leader Award

Overview

Best Publications

• Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo.

  Dominic M. Walsh;Igor Klyubin;Julia V. Fadeeva;William K. Cullen

  5554
  Citations

• Metabotropic glutamate receptors: electrophysiological properties and role in plasticity

  Roger Anwyl

  1179
  Citations

• Dopamine-dependent facilitation of LTP induction in hippocampal CA1 by exposure to spatial novelty

  Shaomin Li;William K. Cullen;Roger Anwyl;Michael J. Rowan

  789
  Citations

• Block of Long-Term Potentiation by Naturally Secreted and Synthetic Amyloid β-Peptide in Hippocampal Slices Is Mediated via Activation of the Kinases c-Jun N-Terminal Kinase, Cyclin-Dependent Kinase 5, and p38 Mitogen-Activated Protein Kinase as well as Metabotropic Glutamate Receptor Type 5

  Qinwen Wang;Dominic M. Walsh;Michael J. Rowan;Dennis J. Selkoe

  677
  Citations

• Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo

  Igor Klyubin;Dominic M Walsh;Dominic M Walsh;Cynthia A Lemere;William K Cullen

  676
  Citations

• Behavioural stress facilitates the induction of long-term depression in the hippocampus

  Lin Xu;Roger Anwyl;Michael J. Rowan

  604
  Citations

• Stimulation on the Positive Phase of Hippocampal Theta Rhythm Induces Long-Term Potentiation That Can Be Depotentiated by Stimulation on the Negative Phase in Area CA1 In Vivo

  Christian Hölscher;Roger Anwyl;Michael J. Rowan

  578
  Citations

• Small-molecule conversion of toxic oligomers to nontoxic β-sheet–rich amyloid fibrils

  Jan Bieschke;Martin Herbst;Martin Herbst;Thomas Wiglenda;Ralf P Friedrich

  504
  Citations

• Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization.

  Igor Klyubin;Vicki Betts;Alfred T. Welzel;Kaj Blennow

  392
  Citations

• Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments.

  William K. Cullen;Yoo-Hun Suh;Roger Anwyl;Michael J. Rowan

  338
  Citations

• Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus

  Lin Xu;Roger Anwyl;Michael J. Rowan

  326
  Citations

• Glucocorticoid receptor and protein/RNA synthesis-dependent mechanisms underlie the control of synaptic plasticity by stress

  Lin Xu;Christian Holscher;Roger Anwyl;Michael J. Rowan

  296
  Citations

• Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

  Linda A. Kotilinek;Marcus A. Westerman;Qinwen Wang;Qinwen Wang;Kimberly Panizzon

  292
  Citations

• β-Amyloid-Mediated Inhibition of NMDA Receptor-Dependent Long-Term Potentiation Induction Involves Activation of Microglia and Stimulation of Inducible Nitric Oxide Synthase and Superoxide

  Qinwen Wang;Michael J. Rowan;Roger Anwyl

  285
  Citations

• Synaptic plasticity in animal models of early Alzheimer's disease

  Michael J Rowan;Igor Klyubin;William K Cullen;Roger Anwyl

  280
  Citations

• Metabotropic glutamate receptor-dependent long-term potentiation

  R. Anwyl

  250
  Citations

• Overcoming the effects of stress on synaptic plasticity in the intact hippocampus: rapid actions of serotonergic and antidepressant agents.

  Alison C. Shakesby;Roger Anwyl;Michael J. Rowan

  245
  Citations

• Modulation of vertebrate neuronal calcium channels by transmitters

  R. Anwyl

  244
  Citations

• Use-dependent effects of amyloidogenic fragments of (beta)-amyloid precursor protein on synaptic plasticity in rat hippocampus in vivo.

  Joung-Hun Kim;Roger Anwyl;Yoo-Hun Suh;Mustafa B. A. Djamgoz

  242
  Citations

• GluN2B subunit-containing NMDA receptor antagonists prevent Aβ-mediated synaptic plasticity disruption in vivo

  Neng-Wei Hu;Igor Klyubin;Roger Anwyl;Michael J. Rowan

  225
  Citations

• Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation.

  John J. O'Connor;Michael J. Rowan;Roger Anwyl

  223
  Citations