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William L. Klein

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Neuroscience 88 1176 1059 603 529 261 41588
Biology and Biochemistry 88 2639 2424 1373 1236 270 41769

William L. Klein publications per year

The chart shows the history of publications by William L. Klein between 1972 and 2025, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. William L. Klein published across 54 years, from 1972 to 2025, averaging 5.4 papers a year. Output peaked at 21 publications in 2012. 6 of the 293 publications appeared in the last two years.

No. of publications
5 10 15 20
Bar chart. Horizontal axis: year, 1972 to 2025. Vertical axis: number of publications, 0 to 21. Peak 21 publications in 2012. 1972: 1 publication 1973: 0 publications 1974: 0 publications 1975: 0 publications 1976: 0 publications 1977: 1 publication 1978: 3 publications 1979: 2 publications 1980: 4 publications 1981: 2 publications 1982: 3 publications 1983: 5 publications 1984: 3 publications 1985: 5 publications 1986: 4 publications 1987: 3 publications 1988: 8 publications 1989: 1 publication 1990: 3 publications 1991: 1 publication 1992: 2 publications 1993: 2 publications 1994: 6 publications 1995: 4 publications 1996: 5 publications 1997: 1 publication 1998: 7 publications 1999: 1 publication 2000: 6 publications 2001: 2 publications 2002: 7 publications 2003: 7 publications 2004: 7 publications 2005: 11 publications 2006: 6 publications 2007: 7 publications 2008: 13 publications 2009: 16 publications 2010: 15 publications 2011: 8 publications 2012: 21 publications 2013: 12 publications 2014: 12 publications 2015: 10 publications 2016: 7 publications 2017: 6 publications 2018: 5 publications 2019: 7 publications 2020: 8 publications 2021: 4 publications 2022: 7 publications 2023: 6 publications 2024: 1 publication 2025: 5 publications
1972 2025

293 publications in total across all disciplines

View publications per year as a table
William L. Klein: publications per year, 1972 to 2025
Year Publications
1972 1
1973 0
1974 0
1975 0
1976 0
1977 1
1978 3
1979 2
1980 4
1981 2
1982 3
1983 5
1984 3
1985 5
1986 4
1987 3
1988 8
1989 1
1990 3
1991 1
1992 2
1993 2
1994 6
1995 4
1996 5
1997 1
1998 7
1999 1
2000 6
2001 2
2002 7
2003 7
2004 7
2005 11
2006 6
2007 7
2008 13
2009 16
2010 15
2011 8
2012 21
2013 12
2014 12
2015 10
2016 7
2017 6
2018 5
2019 7
2020 8
2021 4
2022 7
2023 6
2024 1
2025 5
Total 293
Download as CSV

William L. Klein publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where William L. Klein sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 86 bars. Horizontal axis: publications, 38–47 to 887+. Vertical axis: number of scientists, 0 to 539. Most scientists, 539, have 98–107 publications. The last bar groups every scientist with 887 publications or more. The highlighted bar, 258–267 publications, is where this scientist sits. 38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientist 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38–47 publications 887+

This scientist: 261 publications — 76th percentile

76% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

View publications distribution as a table
Number of Neuroscience scientists by publication count, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
Publications Scientists This scientist
38–47 18
48–57 79
58–67 193
68–77 323
78–87 406
88–97 452
98–107 539
108–117 505
118–127 522
128–137 469
138–147 456
148–157 459
158–167 397
168–177 383
178–187 350
188–197 302
198–207 306
208–217 262
218–227 242
228–237 220
238–247 203
248–257 174
258–267 176 261
268–277 175
278–287 125
288–297 116
298–307 127
308–317 128
318–327 99
328–337 89
338–347 78
348–357 96
358–367 66
368–377 59
378–387 65
388–397 54
398–407 48
408–417 49
418–427 34
428–437 31
438–447 30
448–457 31
458–467 36
468–477 40
478–487 35
488–497 30
498–507 23
508–517 26
518–527 20
528–537 23
538–547 20
548–557 20
558–567 17
568–577 14
578–587 20
588–597 20
598–607 19
608–617 18
618–627 17
628–637 11
638–647 11
648–657 11
658–667 8
668–677 7
678–687 11
688–697 10
698–707 4
708–717 6
718–727 5
728–737 5
738–747 9
748–757 9
758–767 3
768–777 7
778–787 7
788–797 6
798–807 2
808–817 2
818–827 7
828–837 0
838–847 9
848–857 3
858–867 1
868–877 3
878–886 6
887+ 100
Download as CSV

William L. Klein D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where William L. Klein sits on this spectrum.

No. of scientists
100 200 300 400 500
Bar chart with 68 bars. Horizontal axis: D-Index, 30–31 to 163+. Vertical axis: number of scientists, 0 to 512. Most scientists, 512, have 46–47 D-Index. The last bar groups every scientist with 163 D-Index or more. The highlighted bar, 88–89 D-Index, is where this scientist sits. 30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30–31 D-Index 163+

This scientist: 88 D-Index — 88th percentile

88% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

View D-Index distribution as a table
Number of Neuroscience scientists by D-index, Research.com 2026 ranking edition. Based on 9,597 ranked scientists.
D-Index Scientists This scientist
30–31 42
32–33 172
34–35 296
36–37 435
38–39 459
40–41 456
42–43 467
44–45 478
46–47 512
48–49 435
50–51 425
52–53 418
54–55 392
56–57 357
58–59 334
60–61 328
62–63 260
64–65 278
66–67 239
68–69 250
70–71 210
72–73 200
74–75 189
76–77 170
78–79 146
80–81 113
82–83 126
84–85 100
86–87 84
88–89 99 88
90–91 84
92–93 85
94–95 72
96–97 76
98–99 45
100–101 49
102–103 43
104–105 32
106–107 45
108–109 50
110–111 32
112–113 39
114–115 32
116–117 29
118–119 27
120–121 19
122–123 23
124–125 27
126–127 16
128–129 24
130–131 13
132–133 21
134–135 17
136–137 14
138–139 15
140–141 10
142–143 10
144–145 13
146–147 9
148–149 8
150–151 6
152–153 6
154–155 7
156–157 7
158–159 10
160–161 4
162 8
163+ 100
Download as CSV

Research.com Recognitions

  • 2010 - Fellow of American Physical Society (APS) Citation For seminal contributions in the physics of nucleation and phase transitions arising from fundamental advances in statistical fieldtheoretic techniques, and their application to general mean field systems
  • 1989 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1968 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

William L. Klein is a researcher affiliated with Northwestern University in the United States. Their work primarily spans the fields of Medicine, Neuroscience, and Biochemistry, Genetics and Molecular Biology, with a focus on several subfields including Physiology, Neurology, Molecular Biology, Cellular and Molecular Neuroscience, and Cell Biology.

The scientist's research topics encompass Alzheimer's disease research and treatments, neuroinflammation and neurodegeneration mechanisms, neuroscience and neuropharmacology research, computational drug discovery methods, cholinesterase and neurodegenerative diseases, dementia and cognitive impairment research, and tryptophan and brain disorders.

Notable recent papers by William L. Klein include:

  • Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain, 2020, Proceedings of the National Academy of Sciences
  • Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease, 2022, Nature Communications
  • Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer's patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability, 2020, Neuropathology and Applied Neurobiology
  • Induction of inverted morphology in brain organoids by vertical-mixing bioreactors, 2021, Communications Biology
  • The Therapeutic and Diagnostic Potential of Amyloid β Oligomers Selective Antibodies to Treat Alzheimer's Disease, 2022, Frontiers in Neuroscience

Frequent co-authors collaborating with William L. Klein include Kirsten L. Viola, Maíra A. Bicca, Andre L.B. Bitencourt, Erika N. Cline, and Adriano Sebollela.

The scientist's publications appear predominantly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Proceedings of the National Academy of Sciences
  • Neuropathology and Applied Neurobiology
  • International Journal of Molecular Sciences
  • Alzheimer s & Dementia Translational Research & Clinical Interventions

William L. Klein has been recognized with several awards, including fellowships in prestigious organizations. These include being named a Fellow of the American Physical Society in 2010, cited for contributions in the physics of nucleation and phase transitions through statistical field-theoretic techniques, and two separate appointments as Fellow of the American Association for the Advancement of Science in 1968 and 1989.

Best Publications

  • Diffusible, nonfibrillar ligands derived from Aβ1–42 are potent central nervous system neurotoxins

    M. P. Lambert;A. K. Barlow;B. A. Chromy;C. Edwards

  • Aβ Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

    Pascale N. Lacor;Maria C. Buniel;Paul W. Furlow;Antonio Sanz Clemente

  • Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss

    Yuesong Gong;Lei Chang;Kirsten L. Viola;Pascale N. Lacor

  • Targeting small Aβ oligomers: the solution to an Alzheimer's disease conundrum?

    William L Klein;Grant A Krafft;Caleb E Finch

  • Synaptic Targeting by Alzheimer's-Related Amyloid β Oligomers

    Pascale N. Lacor;Maria C. Buniel;Lei Chang;Sara J. Fernandez

  • Detection of a biomarker for Alzheimer's disease from synthetic and clinical samples using a nanoscale optical biosensor.

    Amanda J Haes;Lei Chang;William L Klein;Richard P Van Duyne

  • Aβ Oligomers Induce Neuronal Oxidative Stress through an N-Methyl-D-aspartate Receptor-dependent Mechanism That Is Blocked by the Alzheimer Drug Memantine

    Fernanda G. De Felice;Fernanda G. De Felice;Pauline T. Velasco;Mary P. Lambert;Kirsten L. Viola

  • Nanoparticle-Based Detection in Cerebral Spinal Fluid of a Soluble Pathogenic Biomarker for Alzheimer’s Disease*

    Dimitra G. Georganopoulou;Lei Chang;Jwa Min Nam;C. Shad Thaxton

  • A Localized Surface Plasmon Resonance Biosensor: First Steps toward an Assay for Alzheimer's Disease

    Amanda J. Haes;W. Paige Hall;Lei Chang;William L. Klein

  • An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers

    Theresa R. Bomfim;Leticia Forny-Germano;Luciana B. Sathler;Jordano Brito-Moreira

  • Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

    Takayuki Kondo;Masashi Asai;Masashi Asai;Kayoko Tsukita;Yumiko Kutoku

  • Aβ toxicity in Alzheimer's disease: Globular oligomers (ADDLs) as new vaccine and drug targets

    William L Klein

  • The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade

    Erika N. Cline;Maíra Assunção Bicca;Kirsten L. Viola;William L. Klein

  • Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers

    Fernanda G. De Felice;Marcelo N.N. Vieira;Theresa R. Bomfim;Helena Decker

  • Soluble oligomers of β amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus

    Hai Wei Wang;Joseph F. Pasternak;Joseph F. Pasternak;Helen Kuo;Helen Ristic

  • Amyloid beta oligomers induce impairment of neuronal insulin receptors

    Wei Qin Zhao;Fernanda G. De Felice;Sara Fernandez;Hui Chen

  • Self-assembly of Aβ1-42 into globular neurotoxins

    Brett A. Chromy;Richard J. Nowak;Mary P. Lambert;Kirsten L. Viola

  • Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

    Kirsten L. Viola;William L. Klein

  • Cholesterol Modulates α-Secretase Cleavage of Amyloid Precursor Protein

    Steven Bodovitz;William L. Klein

  • Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

    Fernanda G. De Felice;Diana Wu;Mary P. Lambert;Sara J. Fernandez

Frequent Co-Authors

Fernanda G. De Felice
Fernanda G. De Felice Queen's University
Sergio T. Ferreira
Sergio T. Ferreira Federal University of Rio de Janeiro
Caleb E. Finch
Caleb E. Finch University of Southern California
Douglas P. Munoz
Douglas P. Munoz Queen's University
Vinayak P. Dravid
Vinayak P. Dravid Northwestern University
Charles G. Glabe
Charles G. Glabe University of California, Irvine
Stephen G. Sligar
Stephen G. Sligar University of Illinois at Urbana-Champaign
Christian Hölscher
Christian Hölscher Henan University
A. Claudio Cuello
A. Claudio Cuello McGill University
Michelle E. Ehrlich
Michelle E. Ehrlich Icahn School of Medicine at Mount Sinai

External Links

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Related Online Degrees & Career Pathways

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Best Scientists Citing William L. Klein

Nibaldo C. Inestrosa

Nibaldo C. Inestrosa

Pontificia Universidad Católica de Chile

Publications: 86

Fernanda G. De Felice

Fernanda G. De Felice

Queen's University

Publications: 83

George Perry

George Perry

The University of Texas at San Antonio

Publications: 82

Dominic M. Walsh

Dominic M. Walsh

Brigham and Women's Hospital

Publications: 81

David B. Teplow

David B. Teplow

University of California, Los Angeles

Publications: 74

Kaj Blennow

Kaj Blennow

University of Gothenburg

Publications: 73

Henrik Zetterberg

Henrik Zetterberg

University of Gothenburg

Publications: 70

Sergio T. Ferreira

Sergio T. Ferreira

Federal University of Rio de Janeiro

Publications: 70

Dennis J. Selkoe

Dennis J. Selkoe

Brigham and Women's Hospital

Publications: 68

Charles G. Glabe

Charles G. Glabe

University of California, Irvine

Publications: 65

Frank M. LaFerla

Frank M. LaFerla

University of California, Irvine

Publications: 57

Eliezer Masliah

Eliezer Masliah

National Institutes of Health

Publications: 57

Christian Hölscher

Christian Hölscher

Henan University

Publications: 54

Mark A. Smith

Mark A. Smith

Case Western Reserve University

Publications: 49

Michael J. Rowan

Michael J. Rowan

Trinity College Dublin

Publications: 46

D. Allan Butterfield

D. Allan Butterfield

University of Kentucky

Publications: 46

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