Her primary areas of study are Alzheimer's disease, Insulin receptor, Insulin resistance, Endocrinology and Internal medicine. The various areas that Fernanda G. De Felice examines in her Alzheimer's disease study include Biochemistry, Immunology, Hippocampal formation, Cell biology and Amyloid. She has included themes like NMDA receptor and Oxidative stress in her Cell biology study.
Insulin receptor is a primary field of her research addressed under Insulin. Her Insulin resistance research includes elements of Inflammation, Central nervous system and Type 2 diabetes. Her work investigates the relationship between Diabetes mellitus and topics such as Disease that intersect with problems in Neuroscience, Pathogenesis and Bioinformatics.
Her primary areas of investigation include Neuroscience, Disease, Insulin receptor, Synapse and Insulin resistance. The Neuroscience study combines topics in areas such as Alzheimer's disease, Long-term potentiation and Pathogenesis. The study incorporates disciplines such as Biochemistry, Immunology and Amyloid in addition to Alzheimer's disease.
Fernanda G. De Felice combines subjects such as Signal transduction and Type 2 diabetes with her study of Insulin receptor. As a part of the same scientific study, Fernanda G. De Felice usually deals with the Synapse, concentrating on Hippocampal formation and frequently concerns with Cell biology, Oxidative stress, Phosphorylation and Downregulation and upregulation. Her study looks at the relationship between Insulin resistance and topics such as Synaptic plasticity, which overlap with Cognitive decline.
Her scientific interests lie mostly in Neuroscience, Disease, Synaptic plasticity, Insulin resistance and Neuroprotection. The Neuroscience study which covers Long-term potentiation that intersects with Downregulation and upregulation, Human brain and Microgliosis. Her work on Dementia as part of her general Disease study is frequently connected to FNDC5, thereby bridging the divide between different branches of science.
Her research on Synaptic plasticity also deals with topics like
Fernanda G. De Felice mostly deals with Neuroscience, Disease, Neuroprotection, Insulin resistance and Insulin receptor. Her Neuroscience study frequently draws parallels with other fields, such as Long-term potentiation. Her Long-term potentiation course of study focuses on Human brain and Hippocampal formation.
Her work carried out in the field of Disease brings together such families of science as Type 2 diabetes and Bioinformatics. Her Neuroprotection study combines topics from a wide range of disciplines, such as Synapse and Cell biology. Neuroplasticity and Physical exercise is closely connected to Synaptic plasticity in her research, which is encompassed under the umbrella topic of Insulin resistance.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Aβ Oligomers Induce Neuronal Oxidative Stress through an N-Methyl-D-aspartate Receptor-dependent Mechanism That Is Blocked by the Alzheimer Drug Memantine
Fernanda G. De Felice;Fernanda G. De Felice;Pauline T. Velasco;Mary P. Lambert;Kirsten L. Viola.
Journal of Biological Chemistry (2007)
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers
Theresa R. Bomfim;Leticia Forny-Germano;Luciana B. Sathler;Jordano Brito-Moreira.
Journal of Clinical Investigation (2012)
Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers
Fernanda G. De Felice;Marcelo N.N. Vieira;Theresa R. Bomfim;Helena Decker.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Amyloid beta oligomers induce impairment of neuronal insulin receptors
Wei Qin Zhao;Fernanda G. De Felice;Sara Fernandez;Hui Chen.
The FASEB Journal (2008)
Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers
Fernanda G. De Felice;Diana Wu;Mary P. Lambert;Sara J. Fernandez.
Neurobiology of Aging (2008)
Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease
Fernanda G. De Felice;Sergio T. Ferreira.
Diabetes (2014)
Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence.
Jessica Freiherr;Manfred Hallschmid;William H. Frey;Yvonne F. Brünner.
CNS Drugs (2013)
Monoclonal antibodies that target pathological assemblies of Aβ
Mary P. Lambert;Pauline T. Velasco;Lei Chang;Kirsten L. Viola.
Journal of Neurochemistry (2007)
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models
Mychael V. Lourenco;Mychael V. Lourenco;Rudimar L. Frozza;Rudimar L. Frozza;Guilherme B. de Freitas;Guilherme B. de Freitas;Hong Zhang.
Nature Medicine (2019)
Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases.
Sergio T. Ferreira;Marcelo N. N. Vieira;Fernanda G. De Felice.
Iubmb Life (2007)
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