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Biology and Biochemistry
France
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
27946
World Ranking
6862
National Ranking
214

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Uwe Schlattner is affiliated with Grenoble Alpes University in France and has contributed extensively to research at the intersection of biochemistry, genetics, molecular biology, and medicine. Their work spans various scientific disciplines with a strong focus on molecular biology and physiology.

The main fields of study for Schlattner include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broad areas, they have specialized in several subfields such as:

  • Molecular Biology
  • Physiology
  • Renewable Energy, Sustainability and the Environment
  • Surgery
  • Clinical Biochemistry

The research topics covered in their publications encompass:

  • Mechanisms of cancer metastasis
  • Metabolism, Diabetes, and Cancer
  • Adipose Tissue and Metabolism
  • Metalloenzymes and iron-sulfur proteins
  • Pancreatic function and diabetes
  • Muscle Physiology and Disorders
  • Metabolism and Genetic Disorders

Among recent significant papers authored or coauthored by Schlattner are:

  • "Melatonin drives apoptosis in head and neck cancer by increasing mitochondrial ROS generated via reverse electron transport" (2022) published in Journal of Pineal Research
  • "Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress" (2022) published in JCI Insight
  • "Ornithine Transcarbamylase - From Structure to Metabolism: An Update" (2021) published in Frontiers in Physiology
  • "The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor" (2021) published in BMC Biology
  • "Mitochondrial creatine sensitivity is lost in the D2.mdx model of Duchenne muscular dystrophy and rescued by the mitochondrial-enhancing compound Olesoxime" (2023) published in American Journal of Physiology-Cell Physiology

Schlattner's collaborative work includes frequent partnerships with several coauthors, notably:

  • Małgorzata Tokarska-Schlattner (26 joint publications)
  • Stéphane Attia (13 joint publications)
  • Laurence Kay (12 joint publications)
  • Cécile Cottet-Rousselle (11 joint publications)
  • Frédéric Lamarche (9 joint publications)

Their research has been published in a variety of scientific venues, with multiple contributions to:

  • Biophysical Journal (10 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (7 publications)
  • Biochimica et Biophysica Acta (BBA) - Bioenergetics (5 publications)
  • International Journal of Molecular Sciences (3 publications)
  • Molecular Metabolism (3 publications)

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

    Angela Woods;Stephen R. Johnstone;Kristina Dickerson;Fiona C. Leiper

  • The creatine kinase system and pleiotropic effects of creatine

    Theo Wallimann;Malgorzata Tokarska-Schlattner;Uwe Schlattner;Uwe Schlattner

  • Mitochondrial creatine kinase in human health and disease

    Uwe Schlattner;Malgorzata Tokarska-Schlattner;Theo Wallimann

  • Yeast Two-Hybrid, a Powerful Tool for Systems Biology

    Anna Brückner;Cécile Polge;Nicolas Lentze;Daniel Auerbach

  • Dissecting the Role of 5′-AMP for Allosteric Stimulation, Activation, and Deactivation of AMP-activated Protein Kinase

    Marianne Suter;Uwe Riek;Roland Tuerk;Uwe Schlattner

  • Activation of the AMP-activated Protein Kinase by the Anti-diabetic Drug Metformin in Vivo ROLE OF MITOCHONDRIAL REACTIVE NITROGEN SPECIES

    Ming Hui Zou;Stacy S. Kirkpatrick;Bradley J. Davis;John S. Nelson

  • Functions and effects of creatine in the central nervous system.

    Robert H. Andres;Angélique D. Ducray;Uwe Schlattner;Uwe Schlattner;Theo Wallimann

  • New insights into doxorubicin-induced cardiotoxicity: The critical role of cellular energetics

    Malgorzata Tokarska-Schlattner;Michael Zaugg;Christian Zuppinger;Theo Wallimann

  • Insulin Antagonizes Ischemia-induced Thr172 Phosphorylation of AMP-activated Protein Kinase α-Subunits in Heart via Hierarchical Phosphorylation of Ser485/491

    Sandrine Horman;Didier Vertommen;Richard Heath;Dietbert Neumann

  • Some new aspects of creatine kinase (CK): compartmentation, structure, function and regulation for cellular and mitochondrial bioenergetics and physiology.

    Theo Wallimann;Max Dolder;Uwe Schlattner;Michael Eder

  • Cardiac system bioenergetics: metabolic basis of the Frank‐Starling law

    Valdur Saks;Petras P Dzeja;Uwe Schlattner;Marko Vendelin

  • Inhibition of the Mitochondrial Permeability Transition by Creatine Kinase Substrates REQUIREMENT FOR MICROCOMPARTMENTATION

    Max Dolder;Bernd Walzel;Oliver Speer;Uwe Schlattner

  • Identification of phosphorylation sites in AMP-activated protein kinase (AMPK) for upstream AMPK kinases and study of their roles by site-directed mutagenesis.

    Angela Woods;Didier Vertommen;Dietbert Neumann;Roland Türk

  • The mammalian Nm23/NDPK family: from metastasis control to cilia movement.

    Mathieu Boissan;Sandrine Dabernat;Evelyne Peuchant;Uwe Schlattner

  • Activation of protein kinase Cζ by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells

    Zhonglin Xie;Yunzhou Dong;Miao Zhang;Mei Zhen Cui

  • Acute toxicity of doxorubicin on isolated perfused heart: response of kinases regulating energy supply

    Malgorzata Tokarska-Schlattner;Michael Zaugg;Rafaela da Silva;Eliana Lucchinetti

  • NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy

    V. E. Kagan;J. Jiang;Z. Huang;Y. Y. Tyurina

  • AMP-activated Kinase Inhibits the Epithelial Na+ Channel through Functional Regulation of the Ubiquitin Ligase Nedd4-2

    Vivek Bhalla;Nicholas M. Oyster;Adam C. Fitch;Marjolein A. Wijngaarden

  • Functional aspects of the X-ray structure of mitochondrial creatine kinase: A molecular physiology approach

    Uwe Schlattner;Michael Forstner;Michael Eder;Olaf Stachowiak

Frequent Co-Authors

Theo Wallimann
Theo Wallimann ETH Zurich
Richard M. Epand
Richard M. Epand McMaster University
Valdur Saks
Valdur Saks National Institute of Chemical Physics and Biophysics
Valerian E. Kagan
Valerian E. Kagan University of Pittsburgh
Philippe Chavrier
Philippe Chavrier Institute Curie
Imre Berger
Imre Berger University of Bristol
Aurélien Roux
Aurélien Roux University of Geneva
Benoit Viollet
Benoit Viollet Institut Cochin
Andrey V. Kuznetsov
Andrey V. Kuznetsov Innsbruck Medical University
Petras P. Dzeja
Petras P. Dzeja Mayo Clinic

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