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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
15189
World Ranking
14226
National Ranking
262

Overview

Aurélien Roux is affiliated with the University of Geneva in Switzerland and has contributed extensively to the fields of Biochemistry, Genetics, and Molecular Biology. Their research spans a range of subfields including Cell Biology, Molecular Biology, Physiology, Atomic and Molecular Physics, and Optics, as well as Biophysics. The volume of their work shows a particular focus on cellular and molecular mechanisms.

The main topics of Aurélien Roux's research include:

  • Lipid Membrane Structure and Behavior
  • Cellular transport and secretion
  • Cellular Mechanics and Interactions
  • Force Microscopy Techniques and Applications
  • Microtubule and mitosis dynamics
  • Micro and Nano Robotics
  • Advanced Fluorescence Microscopy Techniques

Among their recent papers are contributions to prominent scientific journals with topics centered on cellular membranes and their dynamics, as well as tissue morphogenesis. Selected publications include:

  • ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes (2020, The Journal of Cell Biology)
  • An ESCRT-III Polymerization Sequence Drives Membrane Deformation and Fission (2020, Cell)
  • Passive coupling of membrane tension and cell volume during active response of cells to osmosis (2021, Proceedings of the National Academy of Sciences)
  • Integer topological defects organize stresses driving tissue morphogenesis (2022, Nature Materials)
  • Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation (2020, Nature Cell Biology)

Roux frequently collaborates with other researchers, with notable co-authors including Stefan Matile, Vincent Mercier, Naomi Sakai, Carlès Blanch-Mercader, and Pau Guillamat. These collaborations suggest a strong network of scientific inquiry predominantly within cellular biophysics and related molecular mechanisms.

Their work often appears in a set of recurring publication venues, which include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Zenodo (CERN European Organization for Nuclear Research)
  • Trends in Cell Biology
  • Nature Communications
  • The Journal of Cell Biology

Best Publications

  • Mechanisms of clathrin-mediated endocytosis.

    Marko Kaksonen;Aurélien Roux

  • Dynamin and the Actin Cytoskeleton Cooperatively Regulate Plasma Membrane Invagination by BAR and F-BAR Proteins

    Toshiki Itoh;Kai S. Erdmann;Aurelien Roux;Bianca Habermann

  • Structural Basis of Membrane Invagination by F-BAR Domains

    Adam Frost;Rushika Perera;Aurélien Roux;Krasimir Spasov

  • GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission

    Aurélien Roux;Katherine Uyhazi;Adam Frost;Pietro De Camilli

  • Role of curvature and phase transition in lipid sorting and fission of membrane tubules

    Aurélien Roux;Damien Cuvelier;Pierre Nassoy;Jacques Prost

  • A fluorescent membrane tension probe.

    Adai Colom;Emmanuel Derivery;Saeideh Soleimanpour;Caterina Tomba

  • Membrane fission by dynamin: what we know and what we need to know

    Bruno Antonny;Christopher G. Burd;Pietro de Camilli;Elizabeth H. Chen

  • A minimal system allowing tubulation with molecular motors pulling on giant liposomes

    Aurélien Roux;Giovanni Cappello;Jean Cartaud;Jacques Prost

  • Relaxation of Loaded ESCRT-III Spiral Springs Drives Membrane Deformation.

    Nicolas Chiaruttini;Lorena Redondo-Morata;Adai Colom;Frédéric Humbert

  • Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis.

    Doris Berchtold;Manuele Piccolis;Nicolas Chiaruttini;Isabelle Riezman

  • Nature of curvature coupling of amphiphysin with membranes depends on its bound density

    Benoît Sorre;Andrew Callan-Jones;John Manzi;Bruno Goud

  • Cooperative extraction of membrane nanotubes by molecular motors.

    Cécile Leduc;Otger Campàs;Konstantin B. Zeldovich;Aurélien Roux

  • ALIX- and ESCRT-III–dependent sorting of tetraspanins to exosomes

    Jorge Larios;Vincent Mercier;Aurélien Roux;Jean Gruenberg

  • Membrane curvature controls dynamin polymerization

    Aurélien Roux;Gerbrand Koster;Martin Lenz;Benoît Sorre

  • Cellular uptake of substrate-initiated cell-penetrating poly(disulfide)s.

    Giulio Gasparini;Eun Kyoung Bang;Guillaume Molinard;David V. Tulumello;David V. Tulumello

  • BAR Domain Scaffolds in Dynamin-Mediated Membrane Fission

    Oliver Daumke;Aurélien Roux;Volker Haucke;Volker Haucke

  • Dynamic subunit turnover in ESCRT-III assemblies is regulated by Vps4 to mediate membrane remodelling during cytokinesis.

    Beata E. Mierzwa;Nicolas Chiaruttini;Lorena Redondo-Morata;Joachim Moser von Filseck

  • Fluorescent Flippers for Mechanosensitive Membrane Probes

    Marta Dal Molin;Quentin Verolet;Adai Colom;Romain Letrun

  • Membrane Shape at the Edge of the Dynamin Helix Sets Location and Duration of the Fission Reaction

    Sandrine Morlot;Valentina Galli;Marius Klein;Nicolas Chiaruttini

  • A minimal system allowing tubulation using molecular motors pulling on giant liposomes

    Aurelien Roux;Giovanni Cappello;Jean Cartaud;Jacques Prost

Frequent Co-Authors

Karl-Heinz Glassmeier
Karl-Heinz Glassmeier Technische Universität Braunschweig
J. P. McFadden
J. P. McFadden University of California, Berkeley
Stefan Matile
Stefan Matile University of Geneva
Robert E. Ergun
Robert E. Ergun University of Colorado Boulder
J. A. Sauvaud
J. A. Sauvaud Centre national de la recherche scientifique, CNRS
Vassilis Angelopoulos
Vassilis Angelopoulos University of California, Los Angeles
Wolfgang Baumjohann
Wolfgang Baumjohann Austrian Academy of Sciences
C. W. Carlson
C. W. Carlson University of California, Berkeley
Christopher T. Russell
Christopher T. Russell University of California, Los Angeles
Christopher J. Owen
Christopher J. Owen University College London

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